Differential impact of hepatic deficiency and total body inhibition of MTP on cholesterol metabolism and RCT in mice

Ezetimibe Inhibits Hepatic Niemann-Pick C1-Like 1 to Facilitate Macrophage Reverse Cholesterol Transport in Mice

(2013) Ping Xie et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role the TICE?

(2013) Uwe J.F. Tietge et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1

(2013) Cédric Le May et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

rHDL administration increases reverse cholesterol transport in mice, but is not additive on top of ezetimibe or cholestyramine treatment

(2013) Cyrille Maugeais et al.   ATHEROSCLEROSIS

Scavenger receptor BI and ABCG5/G8 differentially impact biliary sterol secretion and reverse cholesterol transport in mice

(2013) Arne Dikkers et al.   HEPATOLOGY

Lipid Absorption Defects in Intestine-specific Microsomal Triglyceride Transfer Protein and ATP-binding Cassette Transporter A1-deficient Mice

(2013) Jahangir Iqbal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microsomal Triglyceride Transfer Protein Inhibition Induces Endoplasmic Reticulum Stress and Increases Gene Transcription via Ire1α/cJun to Enhance Plasma ALT/AST

(2013) Joby Josekutty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Meta-Analysis of Comparison of Effectiveness of Lowering Apolipoprotein B Versus Low-Density Lipoprotein Cholesterol and Nonhigh-Density Lipoprotein Cholesterol for Cardiovascular Risk Reduction in Randomized Trials

(2012) Jennifer G. Robinson et al.   AMERICAN JOURNAL OF CARDIOLOGY

High-Density Lipoprotein Function, Dysfunction, and Reverse Cholesterol Transport

(2012) Edward A. Fisher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cholesterol Efflux and Atheroprotection

(2012) Robert S. Rosenson et al.   CIRCULATION

Biliary and nonbiliary contributions to reverse cholesterol transport

(2012) Ryan E. Temel et al.   CURRENT OPINION IN LIPIDOLOGY

Antisense oligonucleotides for the treatment of dyslipidaemia

(2012) Maartje E. Visser et al.   EUROPEAN HEART JOURNAL

Lipid-Related Markers and Cardiovascular Disease Prediction

(2012)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein

(2012) Carlos L. J. Vrins et al.   JOURNAL OF LIPID RESEARCH

ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma

(2012) Wijtske Annema et al.   JOURNAL OF LIPID RESEARCH

Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein

(2012) Richard G. Lee et al.   JOURNAL OF LIPID RESEARCH

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

(2012) Marina Cuchel et al.   LANCET

Multiple functions of microsomal triglyceride transfer protein

(2012) M Mahmood Hussain et al.   Nutrition & Metabolism

Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies

(2012) Wijtske Annema et al.   Nutrition & Metabolism

Pharmacologic Suppression of Hepatic ATP-Binding Cassette Transporter 1 Activity in Mice Reduces High-Density Lipoprotein Cholesterol Levels but Promotes Reverse Cholesterol Transport

(2011) Shigenori Yamamoto et al.   CIRCULATION

Phospholipid transfer activity of microsomal triglyceride transfer protein produces apolipoprotein B and reduces hepatosteatosis while maintaining low plasma lipids in mice

(2011) Irani Khatun et al.   HEPATOLOGY

Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice

(2011) Jan Freark de Boer et al.   JOURNAL OF LIPID RESEARCH

Biliary Sterol Secretion Is Not Required for Macrophage Reverse Cholesterol Transport

(2010) Ryan E. Temel et al.   Cell Metabolism

Biliary Sterol Secretion Is Required for Functional In Vivo Reverse Cholesterol Transport in Mice

(2010) Niels Nijstad et al.   GASTROENTEROLOGY

An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption

(2010) Jahangir Iqbal et al.   JOURNAL OF LIPID RESEARCH

Both the Peroxisome Proliferator-Activated Receptor δ Agonist, GW0742, and Ezetimibe Promote Reverse Cholesterol Transport in Mice by Reducing Intestinal Reabsorption of HDL-Derived Cholesterol

(2009) François Briand et al.   CTS-Clinical and Translational Science

Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice

(2009) Harmen Wiersma et al.   HEPATOLOGY

Activation of the Liver X Receptor Stimulates Trans-intestinal Excretion of Plasma Cholesterol

(2009) Jelske N. van der Veen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Scavenger receptor BI facilitates hepatic very low density lipoprotein production in mice

(2009) Harmen Wiersma et al.   JOURNAL OF LIPID RESEARCH

Update on strategies to increase HDL quantity and function

(2009) Danielle Duffy et al.   Nature Reviews Cardiology

Cholesterol Absorption From the Intestine Is a Major Determinant of Reverse Cholesterol Transport From Peripheral Tissue Macrophages

(2008) Ephraim Sehayek et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY