Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis

Comparative gene identification-58/α/β hydrolase domain 5

(2014) Kathrin A. Zierler et al.   CURRENT OPINION IN LIPIDOLOGY

Macrophage CGI-58 Deficiency Activates ROS-Inflammasome Pathway to Promote Insulin Resistance in Mice

(2014) Hongming Miao et al.   Cell Reports

Functional Cardiac Lipolysis in Mice Critically Depends on Comparative Gene Identification-58

(2013) Kathrin A. Zierler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Necrosis-like death can engage multiple pro-apoptotic Bcl-2 protein family members

(2012) Denise Tischner et al.   APOPTOSIS

FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling

(2012) Rudolf Zechner et al.   Cell Metabolism

CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action

(2012) C. C. Lord et al.   DIABETES

Studies on the Substrate and Stereo/Regioselectivity of Adipose Triglyceride Lipase, Hormone-sensitive Lipase, and Diacylglycerol-O-acyltransferases

(2012) Thomas O. Eichmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages

(2012) E Aflaki et al.   Cell Death & Disease

Distinct roles for α-β hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling

(2012) Caleb C. Lord et al.   Adipocyte

Apolipoprotein E Induces Antiinflammatory Phenotype in Macrophages

(2011) Daniel Baitsch et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis

(2011) Elma Aflaki et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages

(2011) Elma Aflaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Macrophage Arginase Expression and Tumor Growth by the Ron Receptor Tyrosine Kinase

(2011) D. R. Sharda et al.   JOURNAL OF IMMUNOLOGY

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

(2011) Guenter Haemmerle et al.   NATURE MEDICINE

Cytokines, macrophage lipid metabolism and foam cells: Implications for cardiovascular disease therapy

(2011) James E. McLaren et al.   PROGRESS IN LIPID RESEARCH

Macrophage Adipose Triglyceride Lipase Deficiency Attenuates Atherosclerotic Lesion Development in Low-Density Lipoprotein Receptor Knockout Mice

(2010) Bart Lammers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

(2010) Prakash G. Chandak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance

(2010) J. Mark Brown et al.   JOURNAL OF LIPID RESEARCH

Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5

(2009) Martina Schweiger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Growth Retardation, Impaired Triacylglycerol Catabolism, Hepatic Steatosis, and Lethal Skin Barrier Defect in Mice Lacking Comparative Gene Identification-58 (CGI-58)

(2009) Franz P. W. Radner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Stearoyl-Coenzyme A Desaturase 1 Dissociates Insulin Resistance and Obesity From Atherosclerosis

(2008) J. Mark Brown et al.   CIRCULATION

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

(2008) Adelheid Kratzer et al.   JOURNAL OF LIPID RESEARCH

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark