CYP2J2 overexpression increases EETs and protects against angiotensin II-induced abdominal aortic aneurysm in mice

Pioglitazone attenuates progression of aortic valve calcification via down-regulating receptor for advanced glycation end products

(2012) Fei Li et al.   BASIC RESEARCH IN CARDIOLOGY

Delivery of AAV2-CYP2J2 Protects Remnant Kidney in the 5/6-Nephrectomized Rat via Inhibition of Apoptosis and Fibrosis

(2012) Gang Zhao et al.   HUMAN GENE THERAPY

Epoxyeicosatrienoic acids protect rat hearts against tumor necrosis factor-α-induced injury

(2012) Gang Zhao et al.   JOURNAL OF LIPID RESEARCH

Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo

(2012) Shuangxi Wang et al.   NATURE MEDICINE

Let-7b Inhibits Human Cancer Phenotype by Targeting Cytochrome P450 Epoxygenase 2J2

(2012) Fuqiong Chen et al.   PLoS One

The roles of CYP450 epoxygenases and metabolites, epoxyeicosatrienoic acids, in cardiovascular and malignant diseases

(2011) Xizhen Xu et al.   ADVANCED DRUG DELIVERY REVIEWS

Statins exert differential effects on angiotensin II-induced atherosclerosis, but no benefit for abdominal aortic aneurysms

(2011) Jian-an Wang et al.   ATHEROSCLEROSIS

Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart

(2011) Matthew L. Edin et al.   FASEB JOURNAL

Soluble epoxide hydrolase inhibition improves myocardial perfusion and function in experimental heart failure

(2011) Nassiba Merabet et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

β-AR Blockers Suppresses ER Stress in Cardiac Hypertrophy and Heart Failure

(2011) Li Ni et al.   PLoS One

Endogenous Epoxygenases Are Modulators of Monocyte/Macrophage Activity

(2011) Jonas Bystrom et al.   PLoS One

Cytochrome P450 epoxygenase CYP2J2 attenuates nephropathy in streptozotocin-induced diabetic mice

(2011) Guangzhi Chen et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Gene Delivery of Cytochrome P450 Epoxygenase Ameliorates Monocrotaline-Induced Pulmonary Artery Hypertension in Rats

(2010) Changlong Zheng et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Effects of Caspase Inhibitor on Angiotensin II-Induced Abdominal Aortic Aneurysm in Apolipoprotein E–Deficient Mice

(2010) Dai Yamanouchi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Efficacy of Simvastatin in Reducing Aortic Dilatation in Mouse Models of Abdominal Aortic Aneurysm

(2010) Jonathan Golledge et al.   CARDIOVASCULAR DRUGS AND THERAPY

Update Information on Drug Metabolism Systems— 2009, Part II. Summary of Information on the Effects of Diseases and Environmental Factors on Human Cytochrome P450 (CYP) Enzymes and Transporters

(2010) Slobodan Rendic et al.   CURRENT DRUG METABOLISM

Increased CYP2J3 Expression Reduces Insulin Resistance in Fructose-Treated Rats and db/db Mice

(2010) X. Xu et al.   DIABETES

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice

(2010) Craig R. Lee et al.   FASEB JOURNAL

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice

(2010) Yangmei Deng et al.   FASEB JOURNAL

Overexpression of Cytochrome P450 Epoxygenases Prevents Development of Hypertension in Spontaneously Hypertensive Rats by Enhancing Atrial Natriuretic Peptide

(2010) B. Xiao et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Vascular smooth muscle cell peroxisome proliferator-activated receptor-γ deletion promotes abdominal aortic aneurysms

(2010) Milton Hamblin et al.   JOURNAL OF VASCULAR SURGERY

ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice

(2009) Lisa A. Cassis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Simvastatin Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-Knockout Mice

(2009) Yali Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of Soluble Epoxide Hydrolase Attenuated Atherosclerosis, Abdominal Aortic Aneurysm Formation, and Dyslipidemia

(2009) Le-Ning Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rosiglitazone Reduces the Development and Rupture of Experimental Aortic Aneurysms

(2009) Alun Jones et al.   CIRCULATION

Selective Inhibitors of CYP2J2 Related to Terfenadine Exhibit Strong Activity against Human Cancers in Vitro and in Vivo

(2009) C. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Delivery of Recombinant Adeno-Associated Virus-Mediated Human Tissue Kallikrein for Therapy of Chronic Renal Failure in Rats

(2008) Ling Tu et al.   HUMAN GENE THERAPY

Soluble Epoxide Hydrolase Inhibitors Reduce the Development of Atherosclerosis in Apolipoprotein E-Knockout Mouse Model

(2008) Arzu Ulu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY