PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment

Molecular characterization of proprotein convertase subtilisin/kexin type 9-mediated degradation of the LDLR

(2012) Yan Wang et al.   JOURNAL OF LIPID RESEARCH

The cytoplasmic domain is not involved in directing Class 5 mutant LDL receptors to lysosomal degradation

(2011) Thea Bismo Strøm et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Specific functions of lysosomal proteases in endocytic and autophagic pathways

(2011) Sabrina Müller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cysteine cathepsins: From structure, function and regulation to new frontiers

(2011) Vito Turk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Interaction between the ligand-binding domain of the LDL receptor and the C-terminal domain of PCSK9 is required for PCSK9 to remain bound to the LDL receptor during endosomal acidification

(2011) K. Tveten et al.   HUMAN MOLECULAR GENETICS

Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors

(2011) Øystein L. Holla et al.   JOURNAL OF LIPID RESEARCH

Regulated intramembrane proteolysis - lessons from amyloid precursor protein processing

(2011) Stefan F. Lichtenthaler et al.   JOURNAL OF NEUROCHEMISTRY

Ligand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3

(2011) Catherine R. Degnin et al.   MOLECULAR BIOLOGY OF THE CELL

Characterization of a naturally occurring degradation product of the LDL receptor

(2011) Kristian Tveten et al.   MOLECULAR GENETICS AND METABOLISM

Regulated Intramembrane Proteolysis: Signaling Pathways and Biological Functions

(2011) Mark Lal et al.   PHYSIOLOGY

Disrupted recycling of the low density lipoprotein receptor by PCSK9 is not mediated by residues of the cytoplasmic domain

(2010) Thea Bismo Strøm et al.   MOLECULAR GENETICS AND METABOLISM

The Role of Calcium in Lipoprotein Release by the Low-Density Lipoprotein Receptor

(2009) Zhenze Zhao et al.   BIOCHEMISTRY

The unique role of proprotein convertase subtilisin/kexin 9 in cholesterol homeostasis

(2009) S. A. Mousavi et al.   JOURNAL OF INTERNAL MEDICINE

A chimeric LDL receptor containing the cytoplasmic domain of the transferrin receptor is degraded by PCSK9

(2009) Øystein L. Holla et al.   MOLECULAR GENETICS AND METABOLISM

LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

(2009) Noam Zelcer et al.   SCIENCE

Cathepsin D: A cellular roadmap

(2008) Nousheen Zaidi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Investigations on the evolutionary conservation of PCSK9 reveal a functionally important protrusion

(2008) Jamie Cameron et al.   FEBS Journal

Mechanism of Low Density Lipoprotein (LDL) Release in the Endosome

(2008) Xabier Arias-Moreno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

(2008) Boyoun Park et al.   NATURE IMMUNOLOGY

Molecular basis for LDL receptor recognition by PCSK9

(2008) H. J. Kwon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor

(2008) D.-W. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic Profiling of γ-Secretase Substrates and Mapping of Substrate Requirements

(2008) Matthew L Hemming et al.   PLOS BIOLOGY

Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking

(2007) Camilla Raiborg et al.   EXPERIMENTAL CELL RESEARCH