Cytochrome P450-mediated metabolism of vitamin D

Vitamin D 25-hydroxylase – Four decades of searching, are we there yet?

(2012) Jinge Zhu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Hypercalcemia, Hypercalciuria, and Elevated Calcitriol Concentrations with Autosomal Dominant Transmission Due toCYP24A1Mutations: Effects of Ketoconazole Therapy

(2012) Peter J. Tebben et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A new insight into the role of rat cytochrome P450 24A1 in metabolism of selective analogs of 1α,25-dihydroxyvitamin D3

(2011) Steve Y. Rhieu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D3 action

(2011) J. Wesley Pike et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D

(2011) Glenville Jones et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

CYP24A1 and kidney disease

(2011) Martin Petkovich et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Bioengineering Anabolic Vitamin D-25-Hydroxylase Activity into the Human Vitamin D Catabolic Enzyme, Cytochrome P450 CYP24A1, by a V391L Mutation

(2011) Martin Kaufmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Defect inCYP24A1, the Vitamin D 24-Hydroxylase Gene, in a Patient with Severe Infantile Hypercalcemia

(2011) Andrew Dauber et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

CYP24A1Mutations in Idiopathic Infantile Hypercalcemia

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Mutations inCYP24A1and Idiopathic Infantile Hypercalcemia

(2011) Karl P. Schlingmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cerebrotendinous xanthomatosis: An inborn error in bile acid synthesis with defined mutations but still a challenge

(2010) Ingemar Björkhem et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CYP24A1 Is an Independent Prognostic Marker of Survival in Patients with Lung Adenocarcinoma

(2010) G. Chen et al.   CLINICAL CANCER RESEARCH

Vitamin D Analogs

(2010) Glenville Jones   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Genetic Disorders and Defects in Vitamin D Action

(2010) Peter J. Malloy et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Update in Vitamin D

(2010) John S. Adams et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Epigenetic silencing of CYP24 in the tumor microenvironment

(2010) Candace S. Johnson et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

CYP24A1-deficient mice as a tool to uncover a biological activity for vitamin D metabolites hydroxylated at position 24

(2010) René St-Arnaud   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

(2010) Thomas J Wang et al.   LANCET

Relation between serum fibroblast growth factor-23 level and mortality in incident dialysis patients: are gender and cardiovascular disease confounding the relationship?

(2010) H. Olauson et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Crystallization and preliminary X-ray diffraction studies of vitamin D3hydroxylase, a novel cytochrome P450 isolated fromPseudonocardia autotrophica

(2009) Yoshiaki Yasutake et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Metabolism of 1α,25-dihydroxyvitamin D2 by human CYP24A1

(2009) Naoko Urushino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chondrocyte-Specific Modulation of Cyp27b1 Expression Supports a Role for Local Synthesis of 1,25-Dihydroxyvitamin D3in Growth Plate Development

(2009) Roy Pascal Naja et al.   ENDOCRINOLOGY

Fibroblast growth factor 23 and its role in phosphate homeostasis

(2009) Isolde Ramon et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The Candidate Oncogene CYP24A1: A Potential Biomarker for Colorectal Tumorigenesis

(2009) Henrik C. Horváth et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Crystal Structure of CYP24A1, a Mitochondrial Cytochrome P450 Involved in Vitamin D Metabolism

(2009) Andrew J. Annalora et al.   JOURNAL OF MOLECULAR BIOLOGY

Cholecalciferol Supplementation Alters Calcitriol-Responsive Monocyte Proteins and Decreases Inflammatory Cytokines in ESRD

(2009) J. R. Stubbs et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1α,25-Dihydroxyvitamin D3†,‡

(2008) Hiroshi Sugimoto et al.   BIOCHEMISTRY

Vitamin D-Binding Protein Influences Total Circulating Levels of 1,25-Dihydroxyvitamin D3but Does Not Directly Modulate the Bioactive Levels of the Hormonein Vivo

(2008) Lee A. Zella et al.   ENDOCRINOLOGY

Physiological Regulation and Disorders of Phosphate Metabolism -Pivotal Role of Fibroblast Growth Factor 23-

(2008) Seiji Fukumoto   INTERNAL MEDICINE

Structural Analysis of CYP2R1 in Complex with Vitamin D3

(2008) Natallia Strushkevich et al.   JOURNAL OF MOLECULAR BIOLOGY