TNF-α promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines

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LPA Receptors: Subtypes and Biological Actions

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TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines

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Involvement of the Lysophosphatidic Acid-Generating Enzyme Autotaxin in Lymphocyte-Endothelial Cell Interactions

(2008) Tae Nakasaki et al.   AMERICAN JOURNAL OF PATHOLOGY

Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint

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Identification of the orphan GPCR, P2Y10 receptor as the sphingosine-1-phosphate and lysophosphatidic acid receptor

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Multiple actions of lysophosphatidic acid on fibroblasts revealed by transcriptional profiling

(2008) Catelijne Stortelers et al.   BMC GENOMICS

Specific and overlapping sphingosine-1-phosphate receptor functions in human synoviocytes: impact of TNF-α

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Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs

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