STARTing to understand MLN64 function in cholesterol transport

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondria: A therapeutic target in neurodegeneration

(2009) Paula I. Moreira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

(2009) Hyock Joo Kwon et al.   CELL

Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism

(2009) Joshua J. Riegelhaupt et al.   JOURNAL OF LIPID RESEARCH

MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein

(2009) Mark Charman et al.   JOURNAL OF LIPID RESEARCH

Mitochondrial Cholesterol Loading Exacerbates Amyloid   Peptide-Induced Inflammation and Neurotoxicity

(2009) A. Fernandez et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial oxidative stress and dysfunction in myocardial remodelling

(2008) H. Tsutsui et al.   CARDIOVASCULAR RESEARCH

Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases

(2008) Sudheer K. Mantena et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation

(2008) Daniel Rodriguez-Agudo et al.   JOURNAL OF LIPID RESEARCH

Fifty years of advances in bile acid synthesis and metabolism

(2008) David W. Russell   JOURNAL OF LIPID RESEARCH