WIP: more than a WASp-interacting protein

Triple-Color FRET Analysis Reveals Conformational Changes in the WIP-WASp Actin-Regulating Complex

(2014) S. Fried et al.   Science Signaling

WIP Provides an Essential Link between Nck and N-WASP during Arp2/3-Dependent Actin Polymerization

(2013) Sara K. Donnelly et al.   CURRENT BIOLOGY

Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration

(2012) A. J. J. Worth et al.   BLOOD

WIP: WASP-interacting proteins at invadopodia and podosomes

(2012) Esther García et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Wiskott–Aldrich Syndrome Protein Deficiency in Innate Immune Cells Leads to Mucosal Immune Dysregulation and Colitis in Mice

(2012) Deanna D. Nguyen et al.   GASTROENTEROLOGY

Stoichiometry of Nck-dependent actin polymerization in living cells

(2012) Jonathon A. Ditlev et al.   JOURNAL OF CELL BIOLOGY

A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP

(2012) Gaetana Lanzi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ubiquitylation-Dependent Negative Regulation of WASp Is Essential for Actin Cytoskeleton Dynamics

(2012) B. Reicher et al.   MOLECULAR AND CELLULAR BIOLOGY

Studying the Dynamics of SLP-76, Nck, and Vav1 Multimolecular Complex Formation in Live Human Cells with Triple-Color FRET

(2012) M. H. Pauker et al.   Science Signaling

T Lymphocyte Myosin IIA is Required for Maturation of the Immunological Synapse

(2012) Sudha Kumari et al.   Frontiers in Immunology

CR16 forms a complex with N-WASP in human testes

(2011) Wenpei Xiang et al.   CELL AND TISSUE RESEARCH

Competition between Blown Fuse and WASP for WIP Binding Regulates the Dynamics of WASP-Dependent Actin Polymerization In Vivo

(2011) Peng Jin et al.   DEVELOPMENTAL CELL

The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling

(2011) R. Calvez et al.   HAEMATOLOGICA

Identification of Fyn as the binding partner for the WASP N-terminal domain in T cells

(2011) M. Sato et al.   INTERNATIONAL IMMUNOLOGY

A peptide derived from the Wiskott-Aldrich syndrome (WAS) protein-interacting protein (WIP) restores WAS protein level and actin cytoskeleton reorganization in lymphocytes from patients with WAS mutations that disrupt WIP binding

(2011) Michel J. Massaad et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Hck Is a Key Regulator of Gene Expression in Alternatively Activated Human Monocytes

(2011) Ashish Bhattacharjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function

(2011) Jordan S. Orange et al.   JOURNAL OF CLINICAL INVESTIGATION

WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity

(2011) Shirly Becker-Herman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional Cooperation between the Proteins Nck and ADAP Is Fundamental for Actin Reorganization

(2011) M. H. Pauker et al.   MOLECULAR AND CELLULAR BIOLOGY

A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells

(2011) Emily J Quann et al.   NATURE IMMUNOLOGY

PKC-θ function at the immunological synapse: prospects for therapeutic targeting

(2011) Alexandra Zanin-Zhorov et al.   TRENDS IN IMMUNOLOGY

Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced  2 integrin high-affinity state

(2010) H. Stabile et al.   BLOOD

Cooperative interactions at the SLP-76 complex are critical for actin polymerization

(2010) Mira Barda-Saad et al.   EMBO JOURNAL

The cortactin-binding domain of WIP is essential for podosome formation and extracellular matrix degradation by murine dendritic cells

(2010) Inmaculada Bañón-Rodríguez et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The mammalian Verprolin, WIRE induces filopodia independent of N-WASP through IRSp53

(2010) Ashish Misra et al.   EXPERIMENTAL CELL RESEARCH

Functional Anatomy of T Cell Activation and Synapse Formation

(2009) David R. Fooksman et al.   Annual Review of Immunology

How depolymerization can promote polymerization: the case of actin and profilin

(2009) Elena G. Yarmola et al.   BIOESSAYS

Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome

(2009) M. Bosticardo et al.   BLOOD

Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP

(2009) H. Falet et al.   BLOOD

Wiskott–Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation

(2009) Gerben Bouma et al.   IMMUNOBIOLOGY

p53-cofactor JMY is a multifunctional actin nucleation factor

(2009) J. Bradley Zuchero et al.   NATURE CELL BIOLOGY

The WAVE regulatory complex is inhibited

(2009) Ayman M Ismail et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

WIP is critical for T cell responsiveness to IL-2

(2009) S. Le Bras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Wave complex is intrinsically inactive

(2009) Emmanuel Derivery et al.   CELL MOTILITY AND THE CYTOSKELETON

WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function

(2008) L. S. Westerberg et al.   BLOOD

WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport

(2008) Kenneth G. Campellone et al.   CELL

A new role for cortactin in invadopodia: Regulation of protease secretion

(2008) E CLARK et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

WASP and WIP regulate podosomes in migrating leukocytes

(2008) Y. CALLE et al.   JOURNAL OF MICROSCOPY

WIP is essential for lytic granule polarization and NK cell cytotoxicity

(2008) K. Krzewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA