ITK tunes IL-4-induced development of innate memory CD8+ T cells in a γδ T and invariant NKT cell-independent manner

Naive and Innate Memory Phenotype CD4+ T Cells Have Different Requirements for Active Itk for Their Development

(2014) J. Hu et al.   JOURNAL OF IMMUNOLOGY

The Tec Kinases Itk and Rlk Regulate NKT Cell Maturation, Cytokine Production, and Survival

(2014) M. Felices et al.   JOURNAL OF IMMUNOLOGY

IL-4R  Expression by Bone Marrow-Derived Cells Is Necessary and Sufficient for Host Protection against Acute Schistosomiasis

(2014) D. R. Herbert et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Innate Memory CD8+ T Cells Are Distinct from Homeostatic Expanded CD8+ T Cells and Rapidly Respond to Primary Antigenic Stimuli

(2013) W. Huang et al.   JOURNAL OF IMMUNOLOGY

The Tec Kinase ITK Regulates Thymic Expansion, Emigration, and Maturation of    NKT Cells

(2013) C. C. Yin et al.   JOURNAL OF IMMUNOLOGY

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

(2013) You Jeong Lee et al.   NATURE IMMUNOLOGY

A Unique Role for ITK in Survival of Invariant NKT Cells Associated with the p53-Dependent Pathway in Mice

(2012) Q. Qi et al.   JOURNAL OF IMMUNOLOGY

Derivation and Maintenance of Virtual Memory CD8 T Cells

(2012) A. D. Akue et al.   JOURNAL OF IMMUNOLOGY

IL-7 signaling must be intermittent, not continuous, during CD8+ T cell homeostasis to promote cell survival instead of cell death

(2012) Motoko Y Kimura et al.   NATURE IMMUNOLOGY

TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation

(2012) R. Nayar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-4 acts as a potent stimulator of IFN-γ expression in CD8+ T cells through STAT6-dependent and independent induction of Eomesodermin and T-bet

(2011) Jennifer A. Oliver et al.   CYTOKINE

KLF13 sustains thymic memory-like CD8+T cells in BALB/c mice by regulating IL-4–generating invariant natural killer T cells

(2011) Dazhi Lai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-2-inducible T Cell Kinase (Itk) Network Edge Dependence for the Maturation ofiNKT Cell

(2010) Qian Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells

(2010) Michael A Weinreich et al.   NATURE IMMUNOLOGY

T-Cell Signaling Regulated by the Tec Family Kinase, Itk

(2010) A. H. Andreotti et al.   Cold Spring Harbor Perspectives in Biology

Enhanced development of CD4+    T cells in the absence of Itk results in elevated IgE production

(2009) Q. Qi et al.   BLOOD

Differential Expression of Interleukin-17A and -17F Is Coupled to T Cell Receptor Signaling via Inducible T Cell Kinase

(2009) Julio Gomez-Rodriguez et al.   IMMUNITY

The antigen-specific CD8+T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

(2009) Catherine Haluszczak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Memory-Like CD8+ T Cells Generated during Homeostatic Proliferation Defer to Antigen-Experienced Memory Cells

(2009) K. P. Cheung et al.   JOURNAL OF IMMUNOLOGY

Tec kinase Itk in   T cells is pivotal for controlling IgE production in vivo

(2009) M. Felices et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA