Imaging COX-2 expression in cancer using PET/SPECT radioligands: current status and future directions

Selecting Potential Targetable Biomarkers for Imaging Purposes in Colorectal Cancer Using TArget Selection Criteria (TASC): A Novel Target Identification Tool

(2014) Marleen van Oosten et al.   Translational Oncology

Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo

(2012) Torsten Kniess et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2)

(2012) Sai Kiran Sharma et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel 5-substituted 1H-tetrazoles as cyclooxygenase-2 (COX-2) inhibitors

(2012) Baker Jawabrah Al-Hourani et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Systematic review and meta-analysis of COX-2 expression and polymorphisms in prostate cancer

(2012) Ning Shao et al.   MOLECULAR BIOLOGY REPORTS

COX2 Expression Predicts Resistance to Chemoradiotherapy in Esophageal Squamous Cell Carcinoma

(2011) Yasunori Akutsu et al.   ANNALS OF SURGICAL ONCOLOGY

Efficient sequential synthesis of PET Probes of the COX-2 inhibitor [11C]celecoxib and its major metabolite [11C]SC-62807 and in vivo PET evaluation

(2011) Misato Takashima-Hirano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

PET imaging of patients with non-small cell lung cancer employing an EGF receptor targeting drug as tracer

(2011) A A Memon et al.   BRITISH JOURNAL OF CANCER

Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer

(2011) M. J. Uddin et al.   Cancer Prevention Research

Synthesis and preliminary in vitro biological evaluation of new carbon-11-labeled celecoxib derivatives as candidate PET tracers for imaging of COX-2 expression in cancer

(2011) Mingzhang Gao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cyclooxygenase-2 in oncogenesis

(2010) Maria Teresa Rizzo   CLINICA CHIMICA ACTA

Preferential up-regulation of heparanase and cyclooxygenase-2 in carcinogenesis of Barrett’s oesophagus and intestinal-type gastric carcinoma

(2010) Ryotaro Sonoda et al.   HISTOPATHOLOGY

Biomarker Expression and Risk of Subsequent Tumors After Initial Ductal Carcinoma In Situ Diagnosis

(2010) K. Kerlikowske et al.   JNCI-Journal of the National Cancer Institute

[123I]-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation

(2010) Md. Jashim Uddin et al.   ACS Medicinal Chemistry Letters

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

Synthesis and evaluation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents

(2009) Md. Jashim Uddin et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression

(2009) Yuji Kuge et al.   NUCLEAR MEDICINE AND BIOLOGY

Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives

(2008) Frank Wuest et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Eicosanoid Modulation in Advanced Lung Cancer: Cyclooxygenase-2 Expression Is a Positive Predictive Factor for Celecoxib + Chemotherapy—Cancer and Leukemia Group B Trial 30203

(2008) Martin J. Edelman et al.   JOURNAL OF CLINICAL ONCOLOGY

Evaluation of [11C]rofecoxib as PET tracer for cyclooxygenase 2 overexpression in rat models of inflammation

(2007) Erik F.J. de Vries et al.   NUCLEAR MEDICINE AND BIOLOGY