Article
Medicine, General & Internal
Dong Eun Lee, Hyun Kim, Kwi Hwa Park, Song Yi Park, Seung Min Park, Yong Hun Jung, Wonjoon Jeong, Kyung Hye Park
Summary: The study found that specialists and individuals willing to donate organs have higher knowledge and attitude scores towards deceased organ and tissue donation. Those who have received education on organ donation also have higher knowledge scores. People with more experience in recommending organ and tissue donation had higher knowledge and attitude scores.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Surgery
A. K. Israni, D. Zaun, J. D. Rosendale, C. Schaffhausen, W. McKinney, J. J. Snyder
Summary: In 2019, there was an increase in both the number of deceased organ donors and organ transplants, which may be linked to the rising death rates of young people due to the opioid epidemic. The data indicates an opportunity to increase transplant numbers by reducing organ discards.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Surgery
Syed A. Husain, Kristen L. King, David C. Cron, Nikole A. Neidlinger, Han Ng, Sumit Mohan, Joel T. Adler
Summary: This study investigated the impact of local market competition and/or organ availability on kidney procurement and utilization. The results showed that lower competition was associated with higher export, while market monopoly was weakly associated with lower discard. Higher organ availability was associated with both export and discard.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Ethics
G. M. Qurashi
Summary: This paper examines the ethical justifiability of the opt-out organ donor register introduced in England in 2019, questioning whether such paradigms for deceased organ donation are ethically sound. The author ultimately challenges the justification of opt-out systems for organ procurement, suggesting that ethical solutions to organ shortage lie elsewhere.
JOURNAL OF MEDICAL ETHICS
(2021)
Editorial Material
Immunology
Judith A. Anesi, Ebbing Lautenbach, Jennifer Han, Dong Heun Lee, Heather Clauss, Antonette Climaco, Richard Hasz, Warren B. Bilker, Esther Molnar, Darcy Alimenti, Sharon West, Pam Tolomeo, Emily A. Blumberg
Summary: The study found that a high percentage of deceased organ donors received antibiotics during their terminal hospitalization, with some potentially receiving redundant antibiotics, indicating a need for better stewardship in antibiotic use in this population.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Surgery
Ane M. Andres, Jose Luis Encinas, Alba Sanchez-Galan, Javier Serradilla Rodriguez, Karla Estefania, Rocio Gonzalez Sacristan, Alida Alcolea, Pilar Serrano, Belen Estebanez, Inigo Velasco Leon, Paula Burgos, Alvaro Gonzalez Rocafort, Bunty Ramchandani, Belen Calderon, Cristina Verdu, Esperanza Jimenez, Paloma Talayero, Pablo Stringa, Itziar de la Pena Navarro, Esther Ramos, Francisco Hernandez Oliveros
Summary: The shortage of pediatric multivisceral donors leads to long waiting times and high mortality rates for pediatric patients. The use of donors after cardiac death, particularly with normothermic regional perfusion, has increased for solid organ transplantation, except for the intestine. This case demonstrates the possibility of reducing waiting time for patients through multivisceral transplantation from donors after cardiac death.
AMERICAN JOURNAL OF TRANSPLANTATION
(2023)
Article
Ethics
Brendan Parent, Olivia S. Kates, Wadih Arap, Arthur Caplan, Brian Childs, Neal W. Dickert, Mary Homan, Kathy Kinlaw, Ayannah Lang, Stephen Latham, Macey L. Levan, Robert D. Truog, Adam Webb, Paul Root Wolpe, Rebecca D. Pentz
Summary: Research involving the recently deceased can fill a research gap and reduce harm to animals and living human subjects. However, it also presents challenges in terms of honoring the donor's legacy, respecting the rights of donor loved ones, resource allocation, and public health. To maintain public trust and ethical advancements in research involving the recently deceased, new empirical ethics questions need to be addressed.
JOURNAL OF MEDICAL ETHICS
(2023)
Article
Surgery
Kathleen Yu, Syed A. Husain, Kristen King, Jacob S. Stevens, Chirag R. Parikh, Sumit Mohan
Summary: Acute kidney injury (AKI) severity is a strong risk factor for kidney nonprocurement in deceased organ donors. Efforts to address the organ shortage should focus on encouraging the procurement and utilization of kidneys from deceased donors with severe AKI, given the large prevalence of donor AKI and successful transplant outcomes with these kidneys.
CLINICAL TRANSPLANTATION
(2022)
Article
Surgery
Kristen L. King, S. Ali Husain, Adler Perotte, Joel T. Adler, Jesse D. Schold, Sumit Mohan
Summary: Deceased donor kidney allocation allows exceptions in special circumstances, but these exceptions are often concentrated in a few outlier centers. The kidneys involved in the exceptions are usually transplanted to larger centers with higher acceptance rates.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
Xingxing S. Cheng, Philip J. Held, Avi Dor, Jennifer L. Bragg-Gresham, Jane C. Tan, John D. Scandling, Glenn M. Chertow, John P. Roberts
Summary: Expanding donor acceptability criteria to include nonstandard donors could be a potential solution to the organ shortage issue. Despite higher costs per organ, kidney transplantation from nonstandard donors remained cost-effective based on contemporary US data, with economies of scale observed in high OPO volume leading to lower costs.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Review
Immunology
Mohamed Eftal Bin Mohamed Ebrahim, Zafar Mohamed Rizvi, Ahmer Hameed, Jerome Laurence, Angela Webster, Elena Cavazzoni, Taina Lee, Lawrence Yuen, Henry Pleass
Summary: It has been found that burn victims may be an additional source of organ donors, but the number of related studies is limited, and information on organ function and complications post-transplantation is scarce, thus caution is advised.
TRANSPLANTATION PROCEEDINGS
(2022)
Article
Surgery
Matthew J. Bock, Gabrielle R. Vaughn, Peter Chau, Jennifer A. Berumen, John J. Nigro, Elizabeth G. Ingulli
Summary: The study suggests that COVID-19 infection in deceased solid organ transplant donors does not affect recipient survival. However, there is a lack of information regarding the selection of COVID-19-positive donors.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Surgery
Emmanouil Giorgakis, Shirin E. Khorsandi, Amit K. Mathur, Lyle Burdine, Wayel Jassem, Nigel Heaton
Summary: The study findings suggest that using older grafts from donors aged 70 years and above can lead to acceptable outcomes in a highly selected cohort at experienced transplant centers. Advanced age should not be considered an absolute contraindication for utilizing DCD grafts from donors aged 70 years and older.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Surgery
Takayuki Yamamoto, Srilakshmi Atthota, Divyansh Agarwal, Kerry Crisalli, Malcolm Macconmara, Tsukasa Nakamura, Richard Teo, Leigh Anne Dageforde, Shoko Kimura, Nahel Elias, Heidi Yeh, Adel Bozorgzadeh, Tatsuo Kawai, James F. Markmann
Summary: This study compares the outcomes of liver allografts preserved using portable normothermic machine perfusion (NMP) and ischemic cold storage (ICS) in liver transplantation procedures. It concludes that NMP can significantly reduce the incidence of early allograft dysfunction, reperfusion syndrome, and ischemic cholangiopathy after donation after circulatory death (DCD) liver transplantation.
Review
Nursing
Amina Silva, Samantha Arora, Sonny Dhanani, Laura Hornby, Marian Luctkar-Flude, Amanda Ross-White, Ken Lotherington, Andrea Rochon, Lindsay Wilson, Marzieh Latifi, Luciana Giorno, Vanessa Silva E. Silva
Summary: This article collates and summarizes the literature on quality improvement tools for the safety of deceased organ donation processes. It adopts the scoping review methodology and aims to provide insights for developing and updating quality improvement tools, guiding future research, and informing policy development in deceased organ donation.
NURSE EDUCATION IN PRACTICE
(2022)