Article
Cardiac & Cardiovascular Systems
Reed Mszar, Daniel J. Friedman, Emily Ong, Chengan Du, Yongfei Wang, Emily P. Zeitler, Shayna D. Cunningham, Joseph Akar, Jeptha P. Curtis, James Freeman
Summary: This observational cohort study analyzed the sex-based differences and outcomes in adults undergoing catheter ablation for AF. Women were found to be older, have more comorbidities, and experience lower quality of life. They also had a higher risk of adverse events and longer hospitalization.
Article
Medicine, General & Internal
Diana Andrada Irimie, Adela Viviana Sitar-Taut, Bogdan Caloian, Florina Fringu, Gabriel Cismaru, Radu Rosu, Mihai Puiu, Ioan Alexandru Minciuna, Gelu Simu, Dumitru Zdrenghea, Dana Pop
Summary: Catheter ablation for women with ischemic heart disease and atrial fibrillation is performed later and involves trying more antiarrhythmic drugs.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Mohit K. Turagam, Petr Neuzil, Boris Schmidt, Tobias Reichlin, Kars Neven, Andreas Metzner, Jim Hansen, Yuri Blaauw, Philippe Maury, Thomas Arentz, Philipp Sommer, Ante Anic, Frederic Anselme, Serge Boveda, Tom Deneke, Stephan Willems, Pepijn van der Voort, Roland Tilz, Moritoshi Funasako, Daniel Scherr, Reza Wakili, Daniel Steven, Josef Kautzner, Johan Vijgen, Pierre Jais, Jan Petru, Julian Chun, Laurent Roten, Anna Fueting, Marc D. Lemoine, Martin Ruwald, Bart A. Mulder, Anne Rollin, Heiko Lehrmann, Thomas Fink, Zrinka Jurisic, Corentin Chaumont, Raquel Adelino, Karin Nentwich, Melanie Gunawardene, Alexandre Ouss, Christian-Hendrik Heeger, Martin Manninger, Jan-Eric Bohnen, Arian Sultan, Petr Peichl, Pieter Koopman, Nicolas Derval, Thomas Kueffer, Vivek Y. Reddy
Summary: This study compared the differences in clinical outcomes between male and female patients undergoing pulsed field ablation (PFA) for atrial fibrillation (AF). The results showed that there were no significant sex differences in clinical effectiveness or safety events after PFA for AF.
Article
Cardiac & Cardiovascular Systems
Signe Westh Christensen, Selina Kikkenborg Berg, Naja Hulvej Rod, Ann-Dorthe Olsen Zwisler, Lau Caspar Thygesen, Signe Stelling Risom
Summary: A moderate-high level of physical activity was found to be associated with a lower risk of serious adverse events in patients undergoing AF and/or AFL ablation, compared to those with low physical activity levels.
Article
Cardiac & Cardiovascular Systems
Luigi Di Biase, Juan Carlos Diaz, Xiao-Dong Zhang, Jorge Romero
Summary: Pulsed field ablation is a novel energy source for the treatment of atrial fibrillation, with advantages in both safety and effectiveness compared to other energy sources, allowing targeted treatment and minimizing damage.
TRENDS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Hassan A. Alhassan, Aleesha Kainat, Joseph Donohue, Scott J. Baumgartner, Harriet Akunor, Samir Saba, Sandeep Jain, Prem Soman
Summary: This study aimed to compare the short-term safety outcomes of atrial fibrillation (AF) ablation therapy in patients with cardiac amyloidosis (CA) and patients with dilated cardiomyopathy (DCM). The researchers used data from the National Inpatient Sample and matched CA and DCM hospitalizations in a 1:5 ratio based on various sociodemographic factors. They found that the short-term safety outcomes and complication rates of AF ablation in CA were similar to those in a propensity score-matched cohort of DCM. Further studies are needed to explore long-term safety outcomes.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Jonathan M. Kalman, Ahmed M. Al-Kaisey, Ramanathan Parameswaran, Joshua Hawson, Robert D. Anderson, Michael Lim, David Chieng, Stephen A. Joseph, Alex McLellan, Joseph B. Morton, Paul B. Sparks, Geoffrey Lee, Prashanthan Sanders, Peter M. Kistler
Summary: This study aimed to determine if the timing of catheter ablation for atrial fibrillation (AF) affects arrhythmia outcomes. The results showed that there was no significant difference in the atrial arrhythmia free survival at 12 months post-ablation between patients who underwent early ablation and those who underwent delayed ablation. Other secondary outcomes also showed no significant difference. Therefore, delaying AF ablation by 12 months for antiarrhythmic drug management does not reduce the efficacy of ablation.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Hifza Buhari, Jiming Fang, Lu Han, Peter C. Austin, Paul Dorian, Cynthia A. Jackevicius, Amy Y. X. Yu, Moira K. Kapral, Sheldon M. Singh, Karen Tu, Dennis T. Ko, Clare L. Atzema, Emelia J. Benjamin, Douglas S. Lee, Husam Abdel-Qadir
Summary: This study aimed to examine the relationship between sex differences in age and cardiovascular care and stroke in atrial fibrillation (AF). The results showed that females had higher rates of stroke in AF even after adjusting for other factors. Older age and inequities in cardiovascular care partially explained the higher stroke rates in females with AF.
EUROPEAN HEART JOURNAL
(2023)
Article
Medicine, General & Internal
Yan Zhang, Jing Yang, Qian Liu, Jinglan Wu, Lei Yin, Jing Lv, Ling You, Yanan Zhang, Lianxia Wang, Yanlei Zhao, Qian Hou, Weilin Jing, Ruiqin Xie
Summary: This study aimed to evaluate the effect of additional catheter ablation on the risk of adverse events during left atrial appendage closure. Data from 361 atrial fibrillation patients were retrospectively analyzed, and the results showed that adding catheter ablation significantly reduced the incidence of device-related thrombus and embolic events. The combined procedure appeared to be a protective factor against these adverse events.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Simone Evers-Dorpfeld, Stefanie Aeschbacher, Elisa Hennings, Ceylan Eken, Michael Coslovsky, Nicolas Rodondi, Juerg H. Beer, Giorgio Moschovitis, Peter Ammann, Richard Kobza, Selinda Ceylan, Melina Krempke, Christine S. Meyer-Zurn, Elisavet Moutzouri, Anne Springer, Christian Sticherling, Leo H. Bonati, Stefan Osswald, Michael Kuehne, David Conen
Summary: In patients with established AF, women had a lower risk of death than men, but there were no sex-specific differences in other adverse outcomes.
Article
Cell Biology
Keisuke Okawa, Satoshi Taya, Takeshi Morimoto, Ryu Tsushima, Yuya Sudo, Ai Sakamoto, Eisuke Saito, Masahiro Sogo, Masatomo Ozaki, Masahiko Takahashi
Summary: This study aimed to investigate the impact of AF ablation on the incidence of cardiovascular events and death in very old nonvalvular AF patients. The results showed that in nonvalvular AF patients aged 80 years and older, those who underwent AF ablation had a significantly lower incidence of cardiovascular events and death compared to those who received medical therapy only.
Review
Cardiac & Cardiovascular Systems
Gianluigi Bisleri, Arjun K. Pandey, Subodh Verma, Syed M. Ali Hassan, Bobby Yanagawa, Masud Khandaker, Mario Gaudino, Andrea M. Russo, Atul Verma, Deepak L. Bhatt, Andrew C. T. Ha
Summary: Hybrid ablation is a novel therapy that combines minimally invasive surgical and percutaneous catheter-based techniques for the management of atrial fibrillation (AF). Observational studies have shown approximately 70% success rates but higher risks compared to catheter-based ablation. Hybrid ablation is typically offered to patients with persistent or longstanding persistent AF, requiring two procedures. While a randomized trial demonstrated its superiority over catheter-based ablation, it also showed higher complication rates. Contemporary studies have shown a decrease in the incidence of serious complications. Additional randomized trials are needed to determine the risks, benefits, and cost effectiveness of hybrid ablation in clinical practice.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Geoffroy Ditac, Pierre Jean Cottinet, Minh Quyen Le, Daniel Grinberg, Josselin Duchateau, Kevin Gardey, Arnaud Dulac, Antoine Deliniere, Christelle Haddad, Julie Boussuge-Roze, Frederic Sacher, Pierre Jais, Philippe Chevalier, Francis Bessiere
Summary: Atrial fibrillation (AF) catheter ablation procedure contributes significantly to GHG emissions, with a carbon footprint of 76.9 kg CO2-e. With approximately 600,000 annual procedures worldwide, AF catheter ablation leads to 125 tons of CO2 emissions every day, equivalent to a daily car ride of 700,000 km. Electrophysiology catheters and patches are identified as the main contributors to the carbon footprint, highlighting the importance of reducing, reusing, and recycling these items.
Article
Cardiac & Cardiovascular Systems
Linh Ngo, Anna Ali, Anand Ganesan, Richard Woodman, Robert Adams, Isuru Ranasinghe
Summary: Females undergoing catheter ablation of atrial fibrillation have a 25% higher risk of procedural complications compared to males, mainly due to increased risk of vascular injury, pericarditis, pericardial effusion, and bleeding. This gender disparity has persisted over time despite a declining complication rate in both genders.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2021)
Article
Cardiac & Cardiovascular Systems
Karim Benali, Paul Khairy, Nefissa Hammache, Adrian Petzl, Antoine Da Costa, Atul Verma, Jason G. Andrade, Laurent Macle
Summary: A systematic review and pooled analysis of randomized control trials showed that catheter ablation of atrial fibrillation is associated with low rates of procedure-related complications and mortality, which have declined over the past decade.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Carola Gianni, Robert C. Canby, Domenico G. Della Rocca, Andrea Natale, Amin Al-Ahmad
Summary: In this case study, a retained lead remnant following incomplete removal of an implantable cardiac defibrillator system implanted via a left femoral approach was successfully extracted with the assistance of laser technology.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Carola Gianni, Domenico G. Della Rocca, Andrea Natale, Rodney P. Horton
Summary: This case study presents a successful pacemaker implantation in a pregnant patient using intracardiac echocardiography and three-dimensional anatomical mapping without the need for radiation.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Atul Verma, Lucas Boersma, David E. Haines, Andrea Natale, Francis E. Marchlinski, Prashanthan Sanders, Hugh Calkins, Douglas L. Packer, John Hummel, Birce Onal, Sofi Rosen, Karl-Heinz Kuck, Gerhard Hindricks, Bradley Wilsmore
Summary: This first-in-human clinical study demonstrates the feasibility and safety of pulsed field ablation (PFA) in achieving effective pulmonary vein isolation for the treatment of paroxysmal or persistent atrial fibrillation.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Marco Valerio Mariani, Agostino Piro, Michele Magnocavallo, Cristina Chimenti, Domenico Della Rocca, Pasquale Santangeli, Andrea Natale, Francesco Fedele, Carlo Lavalle
Summary: This study systematically reviewed the efficacy and safety of catheter ablation for papillary muscle ventricular arrhythmias (PM-VAs). The results showed that catheter ablation is an effective and safe strategy, with an acute success rate of 88.1% and a long-term success rate of 69.2%. Complication rates were relatively low. The use of intracardiac echocardiography, irrigated catheters, and catheters with contact force sensing capability were associated with higher rates of long-term arrhythmia-free outcomes.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2022)
Letter
Cardiac & Cardiovascular Systems
Andrea Natale, Saibal Kar, David Holmes
Article
Cardiac & Cardiovascular Systems
Jonathan C. Hsu, Douglas Gibson, Rajesh Banker, Shephal K. Doshi, Brett Gidney, Tara Gomez, Dror Berman, Keshava Datta, Assaf Govari, Andrea Natale
Summary: The study involved PV isolation in eight healthy pigs using a fully-integrated PFA system, demonstrating effective and durable tissue ablation and PV isolation without collateral damage to adjacent structures. Histological examination confirmed complete transmural cell necrosis around the circumference of the PV ostium at 30 days.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Sanghamitra Mohanty, Andrea Natale
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Review
Cardiac & Cardiovascular Systems
Rishi Charate, Adnan Ahmed, Surya K. Aedma, Vasvi Singh, Jalaj Garg, Naga V. K. Pothineni, Domenico G. Della Rocca, Rakesh Gopinathannair, Andrea Natale, Dhanunjaya Lakkireddy
Summary: This article reviews the latest available data on the diagnosis, management, and intervention of central and peri-device leaks that occur after left atrial appendage closure. The aim is to gain a better understanding of addressing these leaks and determining the most suitable interventions and closure methods based on their cause, size, and operator experience.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Atul E. Verma, David V. Haines, Lucas Boersma, Nitesh Sood, Andrea E. Natale, Francis Marchlinski, Hugh Calkins, Prashanthan L. Sanders, Douglas Packer, Karl-Heinz Kuck, Gerhard Hindricks, Birce Onal, Jeffrey Cerkvenik, Hiroshi B. Tada, David DeLurgio, PULSED AF Investigators
Summary: Pulsed field ablation is an effective and safe method for treating patients with atrial fibrillation. It has comparable effectiveness to traditional catheter ablation but with a lower rate of complications.
Article
Cardiac & Cardiovascular Systems
Domenico G. Della Rocca, Michele Magnocavallo, Christoffel J. Van Niekerk, Thomas Gilhofer, Grace Ha, Gabriele D'Ambrosio, Sanghamitra Mohanty, Carola Gianni, Jennifer Galvin, Giampaolo Vetta, Carlo Lavalle, Luigi Di Biase, Antonio Sorgente, Gian-Battista Chierchia, Carlo de Asmundis, Lukas Urbanek, Boris Schmidt, J. Christoph Geller, Dhanunjaya R. Lakkireddy, Moussa Mansour, Jacqueline Saw, Rodney P. Horton, Douglas Gibson, Andrea Natale
Summary: Chronic kidney disease has prognostic value in patients undergoing percutaneous left atrial appendage occlusion, affecting the risks of thrombo-embolism and major bleeding.
Article
Cardiac & Cardiovascular Systems
Luigi Di Biase, Fengwei Zou, Aung N. Lin, Vito Grupposo, Jacopo Marazzato, Nicola Tarantino, Domenico Della Rocca, Sanghamitra Mohanty, Andrea Natale, Majd Al Deen Alhuarrat, Guy Haiman, David Haimovich, Richard A. Matthew, Jaclyn Alcazar, Graca Costa, Roy Urman, Xiaodong Zhang
Summary: This study aimed to evaluate the feasibility of a new deep learning imaging algorithm in comparison to cardiac computed tomography (CT) for left atrial anatomical rendering during atrial fibrillation (AF) ablation. The algorithm successfully reconstructed the anatomical structures of the left atrium and showed comparable results to CT measurements. The integration of this algorithm with intracardiac echocardiography (ICE) has the potential to streamline the workflow of AF ablation.
Editorial Material
Cardiac & Cardiovascular Systems
Sanghamitra Mohanty, Moussa Mansour, Andrea Natale
Review
Cardiac & Cardiovascular Systems
Andrea Natale, Katja Zeppenfeld, Paolo Della Bella, Xu Liu, Avi Sabbag, Pasquale Santangeli, Philipp Sommer, Christian Sticherling, Xiaodong Zhang, Luigi Di Biase
Summary: This article discusses the history, current state, and future directions of ventricular tachycardia ablation, highlighting the importance of Europace journal as a platform for publishing groundbreaking research in this field.
Article
Cardiac & Cardiovascular Systems
Ayman A. Hussein, M. Craig Delaughter, George Monir, Andrea Natale, Srinivas Dukkipati, Saumil Oza, Emile Daoud, Luigi Di Biase, Moussa Mansour, Robert Fishel, Miguel Valderrabano, Kenneth Ellenbogen, Jose Osorio, Q-FFICIENCY investigators
Summary: Paroxysmal AF ablation with the novel temperature-controlled RF catheter leads to significant improvement in QOL, reduction in AAD use, cardioversion, and cardiovascular hospitalization.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Carola Gianni, Domenico G. Della Rocca, Andrea Natale, Rodney P. Horton
Summary: Percutaneous transcatheter occlusion of the left atrial appendage is an alternative for stroke prevention in high-risk patients. Among the available devices, Watchman, Amulet, WaveCrest, LAmbre, and Lariat are commonly used for interventional left atrial appendage occlusion.
KOREAN CIRCULATION JOURNAL
(2021)