Review
Cardiac & Cardiovascular Systems
Nso Nso, Mahmoud Nassar, Sofia Lakhdar, Sostanie Enoru, Laura Guzman, Vincent Rizzo, Most S. Munira, Farshid Radparvar, Senthil Thambidorai
Summary: Based on the updated evidence, subcutaneous implantable cardioverter-defibrillator (S-ICD) is safer and more effective than transvenous implantable cardioverter-defibrillator (TV-ICD) as it reduces the incidence of pocket complications, lead displacement or fracture, inappropriate sensing, defibrillation lead failure, pneumothorax/hemothorax, device failure, lead erosion, and all-cause mortality.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Badder Kattih, Felix Operhalski, Felicitas Boeckling, Florian Hecker, Felix Michael, Mate Vamos, Stefan H. Hohnloser, Julia W. Erath
Summary: This study evaluated the clinical outcomes of subcutaneous implantable cardioverter-defibrillator (S-ICD) and single-chamber transvenous (TV-ICD) in an all-comers population and found no significant differences in the composite endpoint, including survival, freedom of hospitalization, and device-associated events, between the two.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Michael R. Gold, Johan D. Aasbo, Raul Weiss, Martin C. Burke, Marye J. Gleva, Bradley P. Knight, Marc A. Miller, Claudio D. Schuger, Nathan Carter, Jill Leigh, Amy J. Brisben, Mikhael F. El-Chami
Summary: Infection rates in S-ICD patients are similar to other populations and not associated with systemic blood-borne infections. Late infections are rare and primarily related to system erosion. A high-risk infection cohort can be identified based on multiple predictors.
Article
Geriatrics & Gerontology
Christian Hauck, Andreas Schober, Alexander Schober, Sabine Fredersdorf-Hahn, Ute Hubauer, Andreas Keyser, Lars Maier, Carsten Jungbauer, Ekrem Uecer
Summary: Age is an independent predictor of mortality after ICD implantation for secondary prevention. Mortality rates did not differ significantly between octogenarians and other elderly aged 70-79 years. Appropriate ICD therapy and acute adverse events leading to surgical intervention were not age-related.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Fozia Z. Ahmed, Carina Blomstrom-Lundqvist, Heather Bloom, Christopher Cooper, Christopher Ellis, Andreas Goette, Arnold J. Greenspon, Charles J. Love, Jens Brock Johansen, Francois Philippon, Khaldoun G. Tarakji, Reece Holbrook, Lou Sherfesee, Ying Xia, Swathi Seshadri, Daniel R. Lexcen, Andrew D. Krahn
Summary: The PADIT infection risk score, developed from a large dataset, identified five independent predictors of CIED infection. A validation study using U.S. healthcare claims data confirmed the predictive value of the risk score, especially when combined with prior CIED infection history, in identifying high-risk patients for targeted interventions to reduce CIED infection risk.
Review
Medicine, General & Internal
Riccardo Vio, Enrico Forlin, Viktor Culic, Sakis Themistoclakis, Riccardo Proietti, Paolo China
Summary: This systematic review focuses on the type, techniques, complications, and success rate of S-ICD lead extraction (SLE). A total of 30 studies with 207 patients undergoing SLE were included. The majority of SLEs were performed for non-infective causes, and there is a need for dedicated tools and standardized approaches in the future. Authors are encouraged to share their experience and data to further improve current approaches.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Psychiatry
Nanna Lindekilde, Ole Skov, Soren J. Skovbakke, Jens B. Johansen, Jens C. Nielsen, Susanne S. Pedersen
Summary: This study examined the associations between baseline anxiety and depression and the occurrence of ICD shocks and risk of mortality in patients with an implantable cardioverter defibrillator (ICD). The results showed no association between baseline anxiety or depression and the occurrence of ICD shocks, but a significant association between baseline anxiety or depression and increased risk of mortality. Therefore, including baseline anxiety and depression in risk stratification of mortality may be necessary.
GENERAL HOSPITAL PSYCHIATRY
(2022)
Article
Cardiac & Cardiovascular Systems
Thomas Olsen, Ole Dan Jorgensen, Jens Cosedis Nielsen, Anna Margrethe Thogersen, Berit Thornvig Philbert, Maria Hee Jung Park Frausing, Niels Christian Foldager Sandgaard, Jens Brock Johansen
Summary: This study aimed to identify patient-related risk factors for cardiac implantable electronic device (CIED) infections. The study found that CIED reoperations, young age, prior valvular surgery, severe renal insufficiency, and dermatitis were associated with a higher risk of CIED infections.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Arwa Younis, Jeffrey J. Goldberger, Valentina Kutyifa, Wojciech Zareba, Bronislava Polonsky, Helmut Klein, Mehmet K. Aktas, David Huang, James Daubert, Mark Estes, David Cannom, Scott McNitt, Kenneth Stein, Ilan Goldenberg
Summary: A personalized ICD benefit prediction score has been developed to assess the likelihood of prophylactic ICD benefit by integrating the risks of ventricular tachycardia/ventricular fibrillation and non-arrhythmic mortality. Three different benefit groups were identified, based on the predicted risks, providing a reference for decision-making on prophylactic ICD implantation.
EUROPEAN HEART JOURNAL
(2021)
Article
Medicine, General & Internal
Marco Canepa, Pietro Palmisano, Gabriele Dell'Era, Matteo Ziacchi, Ernesto Ammendola, Michele Accogli, Eraldo Occhetta, Mauro Biffi, Gerardo Nigro, Pietro Ameri, Giulia Stronati, Italo Porto, Antonio Dello Russo, Federico Guerra
Summary: This study evaluated the accuracy and usefulness of the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) score in predicting the risk of non-sudden death in heart failure patients with reduced ejection fraction (HFrEF) receiving an implantable cardioverter-defibrillator (ICD). The results showed that the MAGGIC score accurately predicted the competing risk of non-sudden death, suggesting that mortality risk estimation should be taken into greater consideration at the time of ICD implantation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Marie Lewenhardt, Fabienne Kreimer, Assem Aweimer, Andreas Pflaumbaum, Andreas Muegge, Michael Gotzmann
Summary: This study analyzed the outcomes of patients of different age groups who received implantable cardioverter-defibrillators (ICD). The results suggest that the indication for primary prophylactic ICD in elderly and very old patients should be critically evaluated. However, age should not be a factor in denying secondary prophylactic ICD implantation.
CLINICAL CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Johanna B. Tonko, Christopher A. Rinaldi
Summary: Implantable cardioverter-defibrillators (ICDs) have revolutionized the treatment of cardiac diseases. However, there is a need for alternative ICD configurations due to expanding patient groups and increasing complications associated with traditional devices.
Review
Cardiac & Cardiovascular Systems
Szymon Budrejko, Maciej Kempa, Andrzej Przybylski
Summary: An implantable cardioverter-defibrillator (ICD) has been developed to protect against sudden cardiac death. However, traditional transvenous ICDs have limitations such as the need for vascular access and the potential for complications like lead failure and infections. To overcome these limitations, a subcutaneous implantable cardioverter-defibrillator (S-ICD) was developed. The utilization of this modern treatment method is increasing globally, and new centers are incorporating the implantation of the S-ICD system.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Mariusz Klopotowski, Krzysztof Kukula, Jacek Jamiolkowski, Artur Oreziak, Maciej Dabrowski, Zbigniew Chmielak, Adam Witkowski
Summary: Hello, the aim of this study was to investigate how the calculated SCD risk in HCM patients with an ICD implanted in the past changed over time. The results showed that SCD risk in HCM patients is usually stable or gets lower, suggesting the need for re-evaluating the risk profile when considering ICD re-implantation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Sarah Wolf, Gregor Goetz, Bernhard Wernly, Claudia Wild
Summary: This systematic review evaluated the clinical effectiveness and safety of subcutaneous implantable cardioverter-defibrillator (S-ICD) in patients at an increased risk of sudden cardiac death. The results showed that S-ICD was non-inferior to TV-ICD in terms of inappropriate shocks and device-related complications. However, evidence regarding appropriate and inappropriate shocks was inconclusive and there was no significant difference in overall mortality and shock efficacy between S-ICD and TV-ICD.
Article
Immunology
Merit P. George, Zerelda Esquer Garrigos, Prakhar Vijayvargiya, Nandan S. Anavekar, Sushil Allen Luis, Walter R. Wilson, Larry M. Baddour, M. Rizwan Sohail
Summary: The study found that distinguishing between infectious and noninfectious lead echodensities in CIED lead infection using TEE without clinical and microbiological parameters is challenging. Without this knowledge, there is limited diagnostic performance based solely on echocardiographic characteristics such as size and mobility. Reanalysis of current criteria for diagnosing CIED lead infection may be necessary.
CLINICAL INFECTIOUS DISEASES
(2021)
Review
Immunology
Tarek Kashour, Rabih Halwani, Yaseen M. Arabi, M. Rizwan Sohail, John C. O'Horo, Andrew D. Badley, Imad M. Tleyjeh
Summary: COVID-19, caused by SARS-CoV-2, poses a high risk for patients with underlying cardiovascular conditions and can lead to various cardiovascular complications. Statins have shown lipid-lowering and cardiovascular protective effects, as well as other beneficial properties, making them a potential candidate for treating COVID-19.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
(2021)
Review
Infectious Diseases
Hassan Ishaq, Wajeeha Tariq, Khawaja Muhammad Talha, Bharath Raj Varatharaj Palraj, M. Rizwan Sohail, Larry M. Baddour, Maryam Mahmood
Summary: Overall mortality and complicated bacteremia were not significantly associated with high vancomycin MICs in patients with MRSAB. Early mortality was significantly associated with low vancomycin MIC, while mortality in studies using broth microdilution method and need for mechanical ventilation were significantly associated with high vancomycin MIC. Further randomized controlled trials are needed to assess the predictive value of vancomycin MIC values for mortality and other adverse clinical outcomes in patients with MRSAB.
Editorial Material
Infectious Diseases
Cristina Corsini Campioli, John Raymond Go, Madiha Fida, Douglas Challener, Muhammad Rizwan Sohail, Omar Abu Saleh, Sarwat Khalil
SEXUALLY TRANSMITTED INFECTIONS
(2021)
Article
Immunology
Zerelda Esquer Garrigos, Deeksha Jandhyala, Prakhar Vijayvargiya, Natalia E. Castillo Almeida, Pooja Gurram, Cristina G. Corsini Campioli, John M. Stulak, Stacey A. Rizza, John C. O'Horo, Daniel C. DeSimone, Larry M. Baddour, M. Rizwan Sohail
Summary: Patients with LVAD-related BSI are at high risk of relapse, so CAS therapy may be a reasonable approach in managing these cases. On the other hand, routine use of CAS therapy may be unnecessary for non-LVAD BSIs.
OPEN FORUM INFECTIOUS DISEASES
(2021)
Letter
Infectious Diseases
Madiha Fida, Omar Abu Saleh, Larry M. Baddour, M. Rizwan Sohail
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Infectious Diseases
Khawaja M. Talha, Hassan Ishaq, Rommel Ramesh, Wajeeha Tariq, Verda Arshad, Larry M. Baddour, M. Rizwan Sohail, Raj Palraj
Summary: The study aimed to determine the role of high VMIC in predicting clinical outcomes in patients with MRSAB but found that it was not significantly associated with in-hospital mortality, median duration of bacteremia, and metastatic infectious complications. Septic arthritis associated with low VMIC was significant.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Larry M. Baddour, Aylin Shafiyi, Brian D. Lahr, Nandan S. Anavekar, James M. Steckelberg, Walter R. Wilson, M. Rizwan Sohail, Daniel C. DeSimone
Summary: This study aimed to investigate the incidence of infective endocarditis in a population in six counties of southern Minnesota between 2014 and 2018. The results showed that the incidence rate increased exponentially with age and was significantly higher in men compared to women.
MAYO CLINIC PROCEEDINGS
(2021)
Article
Cardiac & Cardiovascular Systems
Nana Aburjania, Christine M. Hay, Muhammad R. Sohail
Summary: Diagnosis and treatment of LVAD infections are challenging, with no clinical trials evaluating the best approach currently available. The presence of an implantable device in patients adds to the difficulty of treatment.
ANNALS OF CARDIOTHORACIC SURGERY
(2021)
Article
Infectious Diseases
Cristina Corsini Campioli, Natalia E. Castillo Almeida, John C. O'Horo, Walter R. Wilson, Edison Cano, Daniel C. DeSimone, Larry M. Baddour, M. Rizwan Sohail
Summary: This retrospective study investigated adult patients with monomicrobial brain abscesses caused by gram-positive and gram-negative bacteria. The study found that brain abscesses caused by gram-negative bacteria were more likely to occur in patients with a history of head and neck surgery. In terms of treatment failure, gram-negative bacteria had a higher rate compared to gram-positive bacteria.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Editorial Material
Immunology
John Raymond Go, Douglas Challener, Cristina Corsini Campioli, M. Rizwan Sohail, Raj Palraj, Larry M. Baddour, Omar Abu Saleh
Summary: The clinical significance of a single positive blood culture bottle (SPBCB) with Staphylococcus aureus remains unclear, but this study suggests that it is often clinically significant. Patients with SPBCB receive longer courses of antibiotic therapy compared to those with multiple positive bottles, and they have a higher risk of infective endocarditis and mortality.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Article
Immunology
Supavit Chesdachai, Larry M. Baddour, M. Rizwan Sohail, Bharath Raj Palraj, Malini Madhavan, Hussam Tabaja, Madiha Fida, Brian D. Lahr, Daniel C. DeSimone
Summary: The rate of cardiovascular implantable electronic device (CIED) infection following Gram-negative bacteremia (GNB) is relatively low. Accurate classification of CIED infection remains challenging in patients presenting with GNB.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
John Raymond Go, Cristina Corsini Campioli, Daniel DeSimone, Muhammad Rizwan Sohail
Summary: A 78-year-old man with a history of heart failure, who may have acquired S. simulans from feeding cows on a nearby farm, presented with chills and malaise. Following a prolonged extraction procedure for his implantable cardioverter-defibrillator (ICD), he developed septic shock and ultimately succumbed to refractory hypotension and multiorgan failure despite treatment.
Review
Radiology, Nuclear Medicine & Medical Imaging
Faiq Shaikh, Michael Brun Andersen, M. Rizwan Sohail, Francisca Mulero, Omer Awan, Diana Dupont-Roettger, Olga Kubassova, Jamshid Dehmeshki, Sotirios Bisdas
Summary: The clinical management of COVID-19 is challenging, and medical imaging plays a critical role in early detection and clinical monitoring. Chest x-ray and CT are standard imaging modalities for disease status assessment, while AI can enhance predictive power of these approaches.
CURRENT PROBLEMS IN DIAGNOSTIC RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
M. Rizwan Sohail, G. Ralph Corey, Bruce L. Wilkoff, Jeanne E. Poole, Suneet Mittal, Charles Kennergren, Arnold J. Greenspon, Alan Cheng, Jeffrey D. Lande, Daniel R. Lexcen, Khaldoun G. Tarakji
Summary: This study characterized the microbiology of major cardiac implantable electronic device infections during the WRAP-IT study and found that the use of antibacterial envelope significantly reduced pocket infections, especially against Staphylococcus species, the predominant cause of pocket infections.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2021)