Knockdown of DEPTOR inhibits cell proliferation and increases chemosensitivity to melphalan in human multiple myeloma RPMI-8226 cells via inhibiting PI3K/AKT activity

Real-Time Fluorescent Quantitative Polymerase Chain Reaction Study of Polo-Like Kinase-1 in Pterygia

(2013) H Lu et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Effect of β-(3,4-Dihydroxyphenyl) Lactic Acid on Oxidative Stress Stimulated by High Glucose Levels in Human Peritoneal Mesothelial Cells

(2013) H Zhang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Knockdown of c-Met enhances sensitivity to bortezomib in human multiple myeloma U266 cells via inhibiting Akt/mTOR activity

(2011) WENZHONG QUE et al.   APMIS

DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy

(2011) Yongchao Zhao et al.   MOLECULAR CELL

mTOR Generates an Auto-Amplification Loop by Triggering the βTrCP- and CK1α-Dependent Degradation of DEPTOR

(2011) Shanshan Duan et al.   MOLECULAR CELL

Lenalidomide in combination with melphalan and dexamethasone in patients with newly diagnosed AL amyloidosis: a multicenter phase 1/2 dose-escalation study

(2010) P. Moreau et al.   BLOOD

mTORC1 signaling requires proteasomal function and the involvement of CUL4-DDB1 ubiquitin E3 ligase

(2010) Papia Ghosh et al.   CELL CYCLE

Emerging therapies for the treatment of relapsed or refractory multiple myeloma

(2010) Meletios A. Dimopoulos et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

DEPTORexpression and response to thalidomide: toward a new therapeutic target in multiple myeloma?

(2010) Javier de la Rubia et al.   LEUKEMIA & LYMPHOMA

High expression levels of the mammalian target of rapamycin inhibitorDEPTORare predictive of response to thalidomide in myeloma

(2010) Kevin D. Boyd et al.   LEUKEMIA & LYMPHOMA

Antimyeloma Activity of the Orally Bioavailable Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235

(2009) D. W. McMillin et al.   CANCER RESEARCH

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

mTOR and cancer: many loops in one pathway

(2009) Alejo Efeyan et al.   CURRENT OPINION IN CELL BIOLOGY

Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation

(2009) Lindsey A. Allan et al.   FEBS Journal

Mammalian Target of Rapamycin and S6 Kinase 1 Positively Regulate 6-thioguanine-Induced Autophagy

(2008) X. Zeng et al.   CANCER RESEARCH