A novel mutation of the high-temperature requirement A serine peptidase 1 (HTRA1) gene in a Chinese family with cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL)

A Novel Mutation in theHTRA1Gene Identified in Chinese CARASIL Pedigree

(2012) Xiao-Ling Wang et al.   CNS Neuroscience & Therapeutics

The structural basis of mode of activation and functional diversity: A case study with HtrA family of serine proteases

(2011) Nitu Singh et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β1

(2011) Atsushi Shiga et al.   HUMAN MOLECULAR GENETICS

Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL): From Discovery to Gene Identification

(2011) Toshio Fukutake   Journal of Stroke & Cerebrovascular Diseases

A novel mutation in the HTRA1 gene causes CARASIL without alopecia

(2011) Y. Nishimoto et al.   NEUROLOGY

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

A missense HTRA1 mutation expands CARASIL syndrome to the Caucasian population

(2010) M. Mendioroz et al.   NEUROLOGY

Association of HTRA1 Mutations and Familial Ischemic Cerebral Small-Vessel Disease

(2009) Kenju Hara et al.   NEW ENGLAND JOURNAL OF MEDICINE

HtrA1-dependent proteolysis of TGF-β controls both neuronal maturation and developmental survival

(2008) S Launay et al.   CELL DEATH AND DIFFERENTIATION

Extensive loss of arterial medial smooth muscle cells and mural extracellular matrix in cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL)

(2007) Takashi Oide et al.   NEUROPATHOLOGY