Article
Oncology
Asad Ullah, Asim Ahmed, Abdul Qahar Khan Yasinzai, Kue Tylor Lee, Israr Khan, Bina Asif, Imran Khan, Bisma Tareen, Kaleemullah Kakar, Gul Andam, Saleh Heneidi, Jaffar Khan, Hina Khan, Nabin R. Karki, Jaydira Del Rivero, Nagla Abdel Karim
Summary: This study analyzed the demographics, tumor characteristics, treatment modalities, and outcomes of pulmonary sarcomatoid carcinoma (PSC). The results showed that PSC is a rare and aggressive subtype of non-small cell lung cancer, primarily affecting elderly Caucasian males. Treatment with surgery was associated with better survival outcomes.
Article
Endocrinology & Metabolism
Siomui Chong, Liying Huang, Hai Yu, Hui Huang, Wai-kit Ming, Cheong Cheong Ip, Hsin-Hua Mu, Kexin Li, Xiaoxi Zhang, Jun Lyu, Liehua Deng
Summary: This study aimed to establish and verify a predictive nomogram for patients with cutaneous verrucous carcinoma (CVC) and compare it with the conventional American Joint Committee on Cancer (AJCC) staging system. The nomogram performed better than the AJCC staging system in predicting overall survival (OS) for CVC patients, with higher C-index, NRI, IDI, and AUC values. It provides a more accurate prediction of the 3-, 5-, and 8-year OS probabilities for CVC patients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Oncology
Lucas W. Ashley, Kent F. Sutton, Andrew Ju, George Edwards, Melisa Pasli, Arjun Bhatt
Summary: This study analyzed the major types, common treatment pathways, and 5-year survival rate of penile non-SCC. The study found that penile non-SCC encompasses a diverse set of neoplasms, with surgical intervention being the main treatment approach and radiation therapy being less commonly used. Marital status and age were found to have an impact on survival rates.
FRONTIERS IN ONCOLOGY
(2023)
Article
Endocrinology & Metabolism
Shuai Jin, Xiangmei Liu, Dandan Peng, Dahuan Li, Yuan-Nong Ye
Summary: This study aimed to compare and determine the differences in characteristics between anaplastic thyroid carcinoma and primary squamous cell carcinoma of the thyroid and establish prognostic models. The results showed that the prognostic factors were different for the two cancers, indicating the need for different treatment and management plans.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Oncology
Diana Marzic, Blazen Marijic, Tamara Braut, Stefan Janik, Manuela Avirovic, Ita Hadzisejdic, Filip Tudor, Katarina Radobuljac, Miran Coklo, Boban M. Erovic
Summary: IMP3 expression is higher in malignant laryngeal lesions compared to dysplasia and benign lesions, serving as a useful marker to differentiate between invasive and noninvasive lesions. Higher IMP3 expression is associated with worse clinical outcomes in patients with squamous cell carcinoma of the larynx.
Article
Medicine, General & Internal
Matteo Scampa, Daniel F. Kalbermatten, Carlo M. Oranges
Summary: Vulvar squamous cell carcinoma is the most frequent vulvar neoplasia, and surgery is associated with the best overall survival. Age, pathological grade, stage at diagnosis, treatment sequence, and chemotherapy are identified as independent prognostic factors.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Zhongyang Lin, Hanqing Lin, Yuqing Chen, Yuanteng Xu, Xihang Chen, Hui Fan, Xiaobo Wu, Xiaoying Ke, Chang Lin
Summary: The study evaluated long-term survival trends in patients with locally advanced LC who underwent primary TL, showing improved survival rates over time. Factors such as age and lymph node ratio significantly impacted cancer-specific outcomes. The developed predictive nomogram can provide valuable evidence for clinical research and practice.
Article
Otorhinolaryngology
Aihemaiti Wushouer, Wenming Li, Minfa Zhang, Dapeng Lei, Xinliang Pan
Summary: The study found that surgery plus adjuvant radiation/chemotherapy could achieve longer overall survival for patients with advanced laryngeal squamous cell carcinoma. However, there were significant interactions in treatment effects based on primary subsite, T stage, N stage, and insurance status. Surgery plus adjuvant radiation/chemotherapy significantly improved overall survival for patients with supraglottic, T4a, and N + tumors, while no significant differences were observed for patients with glottic, T3, and N0 tumors between surgery and definitive CRT/RT.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Otorhinolaryngology
Wei Ming, Jingjing Zuo, Jibo Han, Jinhui Chen
Summary: The study aimed to construct prognostic models for OS and CSS in patients with T1N0M0 glottic SCC and reassess the effect of surgery alone and radiation alone using PSM. Using the Surveillance, Epidemiology, and End Results database, it was found that patients who underwent primary site surgery had better survival rates, and factors such as surgery, radiation, sequential treatments, and chemotherapy were associated with survival. The nomogram models were established, and PSM was used to compare the effects of surgery and radiation on survival.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Dermatology
Selin Tokez, Marlies Wakkee, Wilner Kan, Zoe C. Venables, Antien L. Mooyaart, Marieke Louwman, Tamar Nijsten, Loes M. Hollestein
Summary: This study investigated the cumulative incidence and disease-specific survival of patients with metastatic cutaneous squamous cell carcinoma (mcSCC) in the Dutch population and assessed patient-based risk factors. The results showed that approximately 2% of cSCCs metastasize, with higher risk for men, increasing age, and immunocompromised patients. The 5-year disease-specific survival for patients with mcSCC was high.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)
Article
Oncology
Fangjie Chen, Long Chen, Yu Zhang, Lei Shi, Hong'en Xu, Tao Song
Summary: This study compared the prognostic significance of adenocarcinoma (AC) and squamous cell carcinoma (SCC) on overall survival (OS) in patients with cervical cancer. The results showed that patients with AC had worse survival rates and the histological subtype of AC was an independent prognostic factor associated with poorer OS.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Qihe Zhang, Huanhuan Wang, Qin Zhao, Yuyu Zhang, Zhuangzhuang Zheng, Shiyu Liu, Zijing Liu, Lingbin Meng, Ying Xin, Xin Jiang
Summary: The study analyzed the survival and potential prognostic factors of 211 patients with laryngeal squamous cell carcinoma (LSCC), and found that clinical stage, pathological differentiation, and alcohol consumption were associated with patients' survival rate.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Kelly G. Paulson, Vinod Ravi, Brian P. Rubin, Min Park, Elizabeth T. Loggers, Lee D. Cranmer, Michael J. Wagner
Summary: Malignant hemangioendothelioma is a rare endothelial cancer with heterogeneous clinical behavior, with the majority being epithelioid. The incidence of hemangioendothelioma in the US is 0.4 cases per million person-years, and the most common presenting sites are the skin and connective tissues. Survival outcomes are poor, with the majority of deaths occurring within the first 2 years.
Article
Oncology
Asad Ullah, Jaffar Khan, Abdul Waheed, Nitasha Sharma, Elizabeth K. Pryor, Tanner R. Stumpe, Luis Velasquez Zarate, Frederick D. Cason, Suresh Kumar, Subhasis Misra, Sravan Kavuri, Hector Mesa, Nitin Roper, Shahin Foroutan, Nabin Raj Karki, Jaydira Del Rivero, William F. Simonds, Nagla Abdel Karim
Summary: Parathyroid carcinoma is a rare endocrine malignancy that mainly affects older Caucasian individuals with a slight male predominance. The majority of patients undergo surgery, with a 5-year survival rate of 84%. Factors such as tumor size, age, sex, race, metastasis, and tumor differentiation are associated with an increased risk of death.
Article
Medicine, General & Internal
Danielle R. L. Brogden, Christos Kontovounisios, Sundhiya Mandalia, Paris Tekkis, Sarah C. Mills
Summary: ASCC incidence is rapidly increasing, with different patterns observed between males and females, as well as different ethnic and social factors influencing the risk and presentation of the disease.
JOURNAL OF CLINICAL MEDICINE
(2021)