Article
Orthopedics
Geise Ferreira da Cruz, Tatiana Mion Lunz, Tatielle Rocha de Jesus, Mariana Braga Costa, Camila Vilarinho Vidigal, Ben-Hur Albergaria, Jose Luiz Marques-Rocha, Valdete Regina Guandalini
Summary: The study investigated the relationship between ASMI and bone mineral density in postmenopausal women and found that ASMI was not associated with BMD.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Endocrinology & Metabolism
Caroline Zaworski, Jonathan Cheah, Matthew F. Koff, Ryan Breighner, Bin Lin, Jonathan Harrison, Eve Donnelly, Emily M. Stein
Summary: This study evaluated texture features as a measure of bone fragility using clinically acquired MRI scans, finding that trabecular bone was more heterogeneous in fracture patients, with greater variability, disorder, and less homogeneity compared to controls.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Obstetrics & Gynecology
Carl Samuelsson, Michael Wilczek, Johan Kalvesten, Abdul Rashid Qureshi, Torkel B. Brismar
Summary: This study aimed to investigate how bone morphology and mineralization change with age in women using digital X-ray radiogrammetry (DXR). The results showed that the inner diameter of the metacarpals increased significantly with age, while bone mineral density decreased. The faster decrease in bone mineral density observed during and after menopause is due to the resorption of the inner cortical surface.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2022)
Article
Acoustics
Piotr Zagorski, Elzbieta Tabor, Katarzyna Martela, Piotr Adamczyk, Wojciech Glinkowski, Wojciech Pluskiewicz
Summary: This study aimed to evaluate the clinical conformity between quantitative ultrasound (QUS) and densitometry in postmenopausal Caucasian women. The study found significant correlations between QUS measurement results and bone mineral density, suggesting that QUS may provide comparable information to dual X-ray absorptiometry (DXA) examinations in this population.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Orthopedics
Chun Yue, Na Ding, Lu-Lu Xu, Ya-Qian Fu, Yuan-Wei Guo, Yan-Yi Yang, Xian-Mei Zhao, Zhi-Feng Sheng
Summary: Peripheral DXA appears to be a reliable tool for prescreening for osteoporosis, accurately measuring bone density and showing positive correlation with other measurement instruments.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Nutrition & Dietetics
Patricia Paula da Fonseca Grili, Camila Vilarinho Vidigal, Geise Ferreira da Cruz, Ben-Hur Albergaria, Jose Luiz Marques-Rocha, Taisa Sabrina Silva Pereira, Valdete Regina Guandalini
Summary: This study aimed to identify nutrient patterns (NPs) and their association with bone mineral density (BMD) categories in postmenopausal women. The results showed that lower consumption of NP1 and NP2 was associated with an increased risk of osteopenia, but not osteoporosis.
Article
Optics
Rui Ding, Jixiang Zhang, Ehsan Koushki, Reza Tayebee, Xianhua Ding
Summary: A new bone densitometry method based on the photoacoustic response of chicken bones under a blue laser beam is disclosed in this work. The frequency and amplitude of the generated PA signals are directly dependent on bone density. This method shows promising results for bone densitometry and evaluation of mineral content in bones.
Article
Nutrition & Dietetics
Mary Jane De Souza, Nicole C. A. Strock, Nancy Williams, Hang Lee, Kristen J. Koltun, Connie Rogers, Mario G. Ferruzzi, Cindy H. Nakatsu, Connie Weaver
Summary: This study evaluated the effects of prune consumption on bone mineral density in postmenopausal women and found that a daily dose of 50 grams of prunes can prevent a decrease in hip bone mineral density. This effect persisted for 12 months with high compliance and retention rates.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Endocrinology & Metabolism
W. D. Leslie, B. Edwards, S. Al-Azazi, L. Yan, L. M. Lix, P. Czaykowski, H. Singh
Summary: The study found that cancer patients who experience fractures have equally poor post-fracture osteoporosis care as cancer-free individuals, indicating a significant care gap that needs to be addressed in both populations.
OSTEOPOROSIS INTERNATIONAL
(2021)
Article
Nutrition & Dietetics
Briana M. Nosal, Junichi R. Sakaki, Zachary Macdonald, Kyle Mahoney, Kijoon Kim, Matthew Madore, Staci Thornton, Thi Dong Binh Tran, George Weinstock, Elaine Choung-Hee Lee, Ock K. Chun
Summary: This study aimed to examine the dose-dependent effects of blackcurrant supplementation on preventing bone loss in adult women. The results showed that blackcurrant supplementation decreased the loss of whole-body bone mineral density and increased the marker of bone formation, P1NP. Further studies with larger samples and different skeletal conditions are needed to confirm these findings.
Article
Nutrition & Dietetics
Sara Quattrini, Barbara Pampaloni, Giorgio Gronchi, Francesca Giusti, Maria Luisa Brandi
Summary: Osteoporosis is a widespread public health issue, and the key to management and prevention lies in the correct lifestyle and proper nutrition. Research has shown that the Mediterranean diet is beneficial for reducing the incidence of chronic diseases and lowering the risk of fractures. Nutritional improvement and dietary surveys can help increase adherence to the Mediterranean diet, which is advantageous for osteoporosis prevention.
Article
Immunology
Anjali Sharma, Donald R. Hoover, Qiuhu Shi, Phyllis C. Tien, Kathleen M. Weber, Jayesh G. Shah, Michael T. Yin
Summary: Among pre-, peri-, and postmenopausal women, low bone mineral density (BMD) was more common in women with HIV compared to those without HIV. HIV infection and menopausal stage were independent predictors of lower BMD and had additive effects on lumbar spine and total hip BMD.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Endocrinology & Metabolism
Gregory A. Kline, Suzanne N. Morin, Lisa M. Lix, William D. Leslie
Summary: This study found that in real-world practice, BMD T-score remains the dominant factor in determining osteoporosis therapy decisions, while factors such as age, prior fracture, or overall fracture risk have less impact.
Article
Endocrinology & Metabolism
L. E. Flores, S. Nelson, N. Waltman, K. Kupzyk, J. Lappe, L. Mack, L. D. Bilek
Summary: This study found that bone structure in post-menopausal women is closely related to levels of physical activity. Increasing physical activity can improve bone structure, particularly in the lower leg.
OSTEOPOROSIS INTERNATIONAL
(2022)
Article
Endocrinology & Metabolism
Emma O. Billington, Rebecca C. Miyagishima, Charley Hasselaar, Mubashir Arain
Summary: We found that more than a third of early menopausal women were concerned about bone loss and future fractures, and approximately half were willing to take a bisphosphonate medication to preserve bone health around the time of menopause.
OSTEOPOROSIS INTERNATIONAL
(2023)
Review
Obstetrics & Gynecology
F. Sultana, S. R. Davis, R. J. Bell, S. Taylor, R. M. Islam
Summary: The association between endogenous testosterone blood concentrations and cognitive performance among postmenopausal women remains inconclusive due to the imprecision of testosterone measurement and the methodological heterogeneity of the included studies.
Review
Obstetrics & Gynecology
S. R. Davis
Summary: This article summarizes some of the known information about testosterone in women, including its actions, consequences of depletion and replacement. It is not a comprehensive review of the literature in this field, but provides some informative insights.
Article
Obstetrics & Gynecology
F. Sultana, S. R. Davis, A. M. Murray, R. L. Woods, J. J. McNeil, R. M. Islam
Summary: This study aimed to explore the associations between sex hormones and cognitive performance in older women. The results showed no associations between sex hormones and cognitive performance, but a correlation was found between low sex hormone binding globulin concentrations and better processing speed.
Letter
Obstetrics & Gynecology
S. R. Davis
Review
Endocrinology & Metabolism
Sasha Taylor, Rakibul M. Islam, Robin J. Bell, Chandima Hemachandra, Susan R. Davis
Summary: This study aims to investigate the associations between endogenous testosterone blood concentrations and muscle mass, strength, and performance in community dwelling women. The review found that there is no association between total testosterone and muscle mass, strength, or performance in women. Although calculated free or bioavailable testosterone showed a positive association with lean muscle mass, no association was found for muscle strength or performance.
CLINICAL ENDOCRINOLOGY
(2023)
Review
Obstetrics & Gynecology
Scott M. Nelson, Susan R. Davis, Sophia Kalantaridou, Mary Ann Lumsden, Nick Panay, Richard A. Anderson
Summary: This systematic review aimed to determine the usefulness of serum anti-Mullerian hormone (AMH) in diagnosing menopause, predicting menopause, or predicting/diagnosing premature ovarian insufficiency (POI). The review found that lower age-specific AMH concentrations were associated with earlier menopause, but AMH alone could not accurately predict the age at menopause. However, undetectable or extremely low AMH levels may assist in the early diagnosis of POI in young women.
HUMAN REPRODUCTION UPDATE
(2023)
Review
Geriatrics & Gerontology
Chandima Hemachandra, Rakibul M. Islam, Robin J. Bell, Farhana Sultana, Susan R. Davis
Summary: This review examines the association between endogenous testosterone blood concentrations and depression in postmenopausal women. The results suggest no significant association between total testosterone or free testosterone and depression, except for one study which found a relationship between bioavailable testosterone and incident depressive symptoms in women at least 21 years postmenopause. However, due to methodological limitations in the included studies, further research using community-based samples and validated depression assessment tools is necessary to address this knowledge gap.
Review
Obstetrics & Gynecology
Chandima Hemachandra, Susan R. Davis, Robin J. Bell, Farhana Sultana, Rakibul M. Islam
Summary: This systematic review examines the association between endogenous DHEA/DHEAS and depression in postmenopausal women. The review concludes that there is no evidence to support a link between these hormones and depression in this population.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2023)
Article
Health Care Sciences & Services
Jasmin Grigg, Victoria Manning, Darren Lockie, Michelle Giles, Robin Bell, Peta Stragalinos, Chloe Bernard, Isabelle Volpe, Christopher J. Greenwood, Liam Smith, Peter Bragge, Dan Lubman
Summary: This study aimed to understand the need and acceptability of brief alcohol intervention in the breast screening setting and collaboratively design an intervention, and to test its effectiveness in improving knowledge and reducing consumption. The study used a mixed methods approach, including a retrospective analysis, a survey, and interviews, followed by a randomized controlled trial. The results are expected to be published in 2023.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Obstetrics & Gynecology
Robin J. Bell, Penelope J. Robinson, Marina A. Skiba, Rakibul M. Islam, Chandima Hemachandra, Susan R. Davis
Summary: A large-scale study found that endometriosis has a significant impact on sick leave and work ability in women, including those without severe symptoms.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2023)
Review
Obstetrics & Gynecology
M. Jahangirifar, E. Fooladi, S. R. Davis, R. M. Islam
Summary: Refugee and asylum seeker women at midlife and beyond face various health challenges, including menopausal symptoms, sexual dysfunctions, and pelvic floor disorders. However, there is limited global knowledge about the prevalence and risk factors of these neglected health issues in this population.
Article
Endocrinology & Metabolism
Jo Wrigglesworth, Ian H. Harding, Rakibul M. Islam, Phillip G. D. Ward, Robyn L. Woods, Robin J. Bell, John J. McNeil, Elsdon Storey, Gary Egan, Anne M. Murray, Ruth E. Trevaks, Stephanie A. Ward, Susan R. Davis, Joanne Ryan
Summary: This study investigated the relationship between circulating sex hormones and structural brain ageing in older women. The findings showed that women with higher levels of DHEA had higher baseline brain ageing, but this association was not significant after controlling for age and other potential confounding factors. Estrone, testosterone, and sex-hormone binding globulin were not associated with brain ageing. Further studies on circulating sex hormones and brain health in postmenopausal women are needed.
CLINICAL ENDOCRINOLOGY
(2023)
Review
Obstetrics & Gynecology
S. R. Davis
Summary: Cardiovascular disease (CVD) is the leading cause of death in older women, and sex hormones, especially estrogens in women, play a crucial role in its development. Low testosterone levels in women may also have detrimental effects on cardiovascular function. Testosterone has been shown to have favorable effects on blood vessel function and blood pressure in postmenopausal women. Animal studies have demonstrated advantageous effects of testosterone on myocardial function and cardiac electrical signaling. However, there is limited human data, mainly consisting of observational and mechanistic studies, on the cardiovascular effects of testosterone in women.
Review
Obstetrics & Gynecology
S. R. Davis, S. Taylor, C. Hemachandra, K. Magraith, P. R. Ebeling, F. Jane, R. M. Islam
Summary: The Practitioner's Toolkit for Managing the Menopause has been revised to ensure that it reflects current best practice, with updated algorithms and supporting information.