Article
Chemistry, Applied
Shimaa Hosny, Gamal A. Gouda, Samy M. Abu-El-Wafa
Summary: A series of new solid Cr(II), Co(II), Cu(II), Pd(II), and Cd(II) chelates were synthesized and characterized. Cu nano complexes showed potential antitumor activity and DNA cleavage ability.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
A. Vijayaraj, R. Prabu, R. Suresh, R. Sangeetha Kumari, V. Kaviyarasan, V. Narayanan, P. Tamizhdurai, V. L. Mangesh, Fatmah Ali Alasmary, Umamaheswari Rajaji, Mani Govindasamy
Summary: This study reports the characterization of several d-f heterobinuclear [GdCuL1-5(bpy)2(NO3)2] complexes based on 2,2'-bipyridyl ligands using spectroscopy and elemental analysis. The complexes were investigated for their luminescence, genetic code properties, catalytic activity, magnetism, and breaking attributes. The [GdCuL1-5(bpy)2(NO3)2] complexes exhibited two one-electron irreversible reduction events and showed ferromagnetic coupling. The inceptive rate of progress for oxidizing 1,2-benzenediol to cyclohexa-3,5-diene-1,2-dione was higher for longer chain complexes. The [GdCuL5(bpy)2(NO3)2] and [GdCuL4(bpy)2(NO3)2] complexes showed strong DNA genetic code properties, and the complexes exhibited singlet oxygen-mediated oxidative rift of circular recombinant plasmid pBR322 cloning vector in the presence of 2-sulfanylethanol.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Green & Sustainable Science & Technology
Shengbo Zhang, Qikun Hu, Yu-Xiao Zhang, Haoyue Guo, Yanfen Wu, Mingze Sun, Xingsong Zhu, Jiangang Zhang, Shuyan Gong, Ping Liu, Zhiqiang Niu
Summary: Plastics are indispensable in modern society, but the continuous growth in production poses threats to human health and ecosystems. To address this, scientists have developed a catalyst that can efficiently degrade various plastics, including PET, and provide a practical solution for sustainable plastic waste management.
NATURE SUSTAINABILITY
(2023)
Article
Chemistry, Inorganic & Nuclear
Natalija Pantalon Juraj, Tana Tandaric, Vanja Tadic, Berislav Peric, Dominik Moreth, Ulrich Schatzschneider, Anamaria Brozovic, Robert Vianello, Srecko Kirin
Summary: In this study, the coordination properties of ligands were investigated by modifying their side chain structure. The results showed that the length of the aliphatic linker, isomers of the amide group, and the type of chiral terminal group all had an impact on the coordination properties. Additionally, DFT calculations provided insights into the stability of isomers and the potential hydrogen bonding between ligands in a ML2 complex.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Applied
Adel Z. El-Sonbati, Mostafa A. Diab, Ahmed K. El-Sayed, Mohamed Abou-Dobara, Sameh A. El-Sayad
Summary: Metal complexes of a Schiff base ligand derived from 2,4-dihydroxybenzaldehyde and p-nitroaniline were synthesized and characterized. The complexes showed antibacterial, antifungal, and cytotoxic activities, and the ligand exhibited high binding affinity to various receptors.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Jan Hormann, Olga Verbitsky, Xiaoyu Zhou, Beatrice Battistella, Margarete van der Meer, Biprajit Sarkar, Cunyuan Zhao, Nora Kulak
Summary: We synthesized and characterized Cu(ii) complexes CuL1-CuL6 with cyclen-based ligands. The ligands L-1-L-6 comprise different donor sets including S and O atoms. The substitution of N donor atoms with hard donor O atoms leads to efficient oxidative nucleases, but dissociation of the complex upon reduction. We are showing that the rational combination of O and S atoms next to two nitrogen donors within the macrocycle leads to the stabilization of both redox states, resulting in the highest oxidative DNA cleavage activity within this family of cyclen-based Cu(ii) complexes.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Mouayed A. Hussein, Adyan A. Yaseen
Summary: A novel copper complex was synthesized and characterized, and its interaction with DNA and antitumor capacity against human colorectal cancer cells were investigated.
TRANSITION METAL CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Jannis Barrera, Haleh H. Haeri, Julian Heinrich, Matthias Stein, Dariush Hinderberger, Nora Kulak
Summary: Cu(ii) complexes with ATCUN peptide ligands were investigated for their ROS generation and oxidative DNA degradation abilities. However, the biological activity of most ATCUN complexes such as Cu-GGH (Gly-Gly-His) is low. Tuning the redox chemistry by incorporating N-heteroaromatics reinstates ROS production, leading to efficient DNA cleavage.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Urszula K. Komarnicka, Sandra Koziel, Barbara Pucelik, Agata Barzowska, Milosz Siczek, Magdalena Malik, Daria Wojtala, Alessandro Niorettini, Agnieszka Kyziol, Victor Sebastian, Pavel Kopel, Stefano Caramori, Alina Bienko
Summary: Novel heteronuclear Ir-III-Cu-II coordination compounds containing phosphines derived from fluoroquinolones have been synthesized and studied as potential anticancer chemotherapeutics. The compounds were characterized using various analytical techniques and their ability to accumulate in cancer cells and induce cell cycle changes was demonstrated. The study highlights the potential of these compounds as targeted cancer therapies.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Sebastian Doniz Kettenmann, Matthew White, Julien Colard-Thomas, Matilda Kraft, Andrea T. Fessler, Karin Danz, Gerhard Wieland, Sylvia Wagner, Stefan Schwarz, Arno Wiehe, Nora Kulak
Summary: Prodigiosenes, a family of red pigments with diverse biological activities, have been modified systematically to assess the impact of hydrophobic substituents on their cytotoxicity, anticancer activity, and antimicrobial activity. The Cu(II) complexes of prodigiosenes demonstrate potential for application in photodynamic therapy, with one derivative lacking any alkyl chain showing promising photoinduced anticancer activity. Additionally, these derivatives and their Cu(II) complexes exhibit antimicrobial activity against Staphylococcus aureus strains.
Article
Chemistry, Physical
Mirjana Antonijevic Nikolic, Branka Drazic, Beata Cristovao, Agata Bartyzel, Barbara Miroslaw, Sladana Tanaskovic
Summary: New cationic complexes of Cu(II) with bridged aminocarboxylates were synthesized and characterized, showing to exist as hydrates. The complexes exhibited anti-proliferative effects on leukemia cell lines with IC50 values ranging from 37.9 to 63.05 µM.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Multidisciplinary
Tilak Naskar, Nabhendu Pal, Amit Majumdar
Summary: The synthesis and characterization of new binuclear Zn(ii) complexes with various ligands were presented in the study. It was found that Zn(ii) cannot mediate the cleavage of thiolates, leading to the isolation of binuclear Zn(ii)-thiolate complexes. Further investigations showed the formation of a new binuclear Zn(ii) complex featuring a bridging S-3(2-) unit through redox reactions involving thiolates and externally added elemental sulfur.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Kamal Hossain, Amit Majumdar
Summary: The synthesis and reactivity of a binuclear zinc complex and an unprecedented binuclear zinc pentasulfido complex were studied. The reaction produced various sulfur compounds through oxidation-reduction reactions. The coordinated ligands and chains in the complexes can be used as catalysts to generate organic sulfur compounds.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Monireh Ghorbanpour, Behzad Soltani, Christopher J. Ziegler, Kazem Jamshidi-Ghaleh
Summary: A pyrazole based ligand containing nitrogen and sulfur donors was synthesized and used to prepare new binuclear Ni(II), Cu(II), and Zn(II) complexes. The ligand and complexes were characterized using spectroscopic and physico-chemical methods, with the Cu(II) complex demonstrating the highest second-order refractive index value.
INORGANICA CHIMICA ACTA
(2021)
Article
Chemistry, Physical
Bhushan S. Sail, Vinod H. Naik, B. M. Prasanna, Naushad Ahmad, Mohammad Rizwan Khan, M. R. Jagadeesh, Ravikumar Cheedarala
Summary: Many Schiff bases derived from 2-hydrazinobenzothiazole and isatin have been used to form [ML2]Cl2 type Co(II) complexes. Nitrogen from azomethine, oxygen from lactonyl, and nitrogen atoms of the thiazole ring contribute to coordinating the metallic ion. The complexes consist entirely of metal and have a geometrical octahedron structure, as confirmed by analytical, magnetic, and spectroscopic investigations.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Yoon Jung Jang, Jong-Moon Kim, Hyun Mee Lee, Biao Jin, Tae-Sub Cho
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2015)
Article
Multidisciplinary Sciences
Yoon Jung Jang, Changyun Lee, Seog K. Kim
SCIENTIFIC REPORTS
(2015)
Article
Biochemistry & Molecular Biology
Jong Heon Shin, Yoon Mo Hwang, Yoon Jung Jang, Seog K. Kim
BIOPHYSICAL CHEMISTRY
(2016)
Article
Materials Science, Multidisciplinary
Hasi Rani Barai, Dong Jin Lee, Sung Wook Han, Yoon Jung Jang
Article
Chemistry, Physical
Yoon Mo Hwang, Nayoung Kwon, Seog K. Kim, Yoon Jung Jane
JOURNAL OF PHYSICAL CHEMISTRY B
(2017)
Article
Chemistry, Multidisciplinary
Yoon Jung Jang, Raeyeong Kim, Nataraj Chitrapriya, Sung Wook Han, Seog K. Kim, Inho Bae
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
(2013)
Article
Chemistry, Physical
Yong Hee Kim, Sang Don Jung, Yoon Jung Jang, Chan Im, Seog K. Kim, Dae Won Cho
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2013)
Article
Biochemistry & Molecular Biology
Panneerselvam Anitha, Nataraj Chitrapriya, Yoon Jung Jang, Periasamy Viswanathamurthi
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2013)
Article
Chemistry, Physical
Yong Hee Kim, Sang Don Jung, Myoung Hee Lee, Chan Im, Yun-Hwa Kim, Yoon Jung Jang, Seog K. Kim, Dae Won Cho
JOURNAL OF PHYSICAL CHEMISTRY B
(2013)
Article
Chemistry, Multidisciplinary
Rajendran Manikandan, Nataraj Chitrapriya, Yoon Jung Jang, Periasamy Viswanathamurthi
Article
Chemistry, Multidisciplinary
Biao Jin, Gi Woong Sung, Yoon Jung Jang
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
(2019)
Article
Spectroscopy
Jong-Moon Kim, Myung Duk Jang, Jin Biao, Yoon Jung Jang
SPECTROSCOPY AND SPECTRAL ANALYSIS
(2018)
Article
Chemistry, Multidisciplinary
Min Ik Kwak, Bo Ram Jeon, Seog K. Kim, Yoon Jung Jang
Meeting Abstract
Biophysics
Seog K. Kim, Yoon Jung Jang
BIOPHYSICAL JOURNAL
(2014)
Article
Biochemistry & Molecular Biology
Michael Ramek, Jasmina Sabolovic
Summary: This paper investigates the geometries, energy landscapes, and magnetic parameters of copper(II) amino acid compounds using density functional theory calculations. The results show that certain conformers with histaminate-like and glycine-like modes have low Gibbs free energies and high metal-binding affinities. The predicted conformations reproduce the experimental electron paramagnetic resonance parameters.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Wei Tian, Wen Zhong, Zengyan Yang, Ling Chen, Shijie Lin, Yanping Li, Yuxing Wang, Peilin Yang, Xing Long
Summary: A series of novel dibutyltin complexes based on salen-like ligands were synthesized and characterized. Complex S03 showed excellent in vitro anticancer activity and induced cancer cell death through multiple mechanisms. This study reveals new mechanisms of organotin complexes and provides new insights into the development of organotin metal complexes as anticancer drugs.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Natalie C. Korkola, Martin J. Stillman
Summary: Many proteins require a metal cofactor for their function, and these metals play a role in protein folding. The study found that the metallation rates of different metal binding pathways are influenced by pH, with the less cooperative pathway being more affected by low pH conditions. Specific mixtures of structures are formed in the initial steps of metallation, and unfolding the disordered apo-MT structure hinders the formation of these preliminary structures. The compact conformation of the native apo-MT allows for rapid formation of metal-thiolate structures with high affinity, providing protection from oxidation.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Boxuan Yang, Xitong Song, Binju Wang
Summary: The diiron active site plays a crucial role in catalytic transformations in both biological and chemical systems. Recent advancements in the field include the synthesis of biomimetic diiron catalysts inspired by the active structure of soluble methane monooxygenase (sMMO), which have been successfully applied to the dehydrogenation of indolines.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Christina N. Banti, Angeliki A. Piperoudi, Catherine P. Raptopoulou, Vassilis Psycharis, Constantinos M. Athanassopoulos, Sotiris K. Hadjikakou
Summary: Two copper(I) polymorphs with mitochondria-targeting properties were successfully prepared via metal ion conjugation. These compounds showed promising activities in DNA binding, enzyme inhibition, and cancer cell inhibition. The molecular mechanisms of action were investigated.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)