Role of Natural Killer Cells in Hematopoietic Stem Cell Transplantation: Myth or Reality?

NK cells expressing inhibitory KIR for non-self-ligands remain tolerant in HLA-matched sibling stem cell transplantation

(2010) A. T. Bjorklund et al.   BLOOD

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

(2010) S. Cooley et al.   BLOOD

Reconstitution of natural killer cell receptors influences natural killer activity and relapse rate after haploidentical transplantation of T- and B-cell depleted grafts in children

(2010) M. M. Pfeiffer et al.   HAEMATOLOGICA

Breaking tolerance to self, circulating natural killer cells expressing inhibitory KIR for non-self HLA exhibit effector function after T cell-depleted allogeneic hematopoietic cell transplantation

(2009) J. Yu et al.   BLOOD

Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity

(2009) C. G. Brunstein et al.   BLOOD

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation

(2009) K Ludajic et al.   BONE MARROW TRANSPLANTATION

Fully functional NK cells after unrelated cord blood transplantation

(2009) V Beziat et al.   LEUKEMIA

CD3+/CD19+-depleted grafts in HLA-matched allogeneic peripheral blood stem cell transplantation lead to early NK cell cytolytic responses and reduced inhibitory activity of NKG2A

(2009) D N Eissens et al.   LEUKEMIA

KIR-ligand incompatibility in the graft-versus-host direction improves outcomes after umbilical cord blood transplantation for acute leukemia

(2009) R Willemze et al.   LEUKEMIA

NK cell education: not an on-off switch but a tunable rheostat

(2009) Petter Brodin et al.   TRENDS IN IMMUNOLOGY

Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation

(2008) L. Vago et al.   BLOOD

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

(2008) S. Cooley et al.   BLOOD

MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

(2008) M. Yawata et al.   BLOOD

Human NK cells: from HLA class I-specific killer Ig-like receptors to the therapy of acute leukemias

(2008) Alessandro Moretta et al.   IMMUNOLOGICAL REVIEWS

Negative signaling by inhibitory receptors: the NK cell paradigm

(2008) Eric O. Long   IMMUNOLOGICAL REVIEWS

Activating KIRs exert a crucial role on relapse and overall survival after HLA-identical sibling transplantation

(2008) Jennifer Schellekens et al.   MOLECULAR IMMUNOLOGY

Donor Killer Immunoglobulin-Like Receptor (KIR) Genotype-Patient Cognate KIR Ligand Combination and Antithymocyte Globulin Preadministration Are Critical Factors in Outcome of HLA-C-KIR Ligand-Mismatched T Cell–Replete Unrelated Bone Marrow Transplantation

(2007) Toshio Yabe et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION