Modeling mitochondrial dysfunctions in the brain: from mice to men

Severe Motor Neuron Degeneration in the Spinal Cord of the Tg2576 Mouse Model of Alzheimer Disease

(2017) Ji-Seon Seo et al.   JOURNAL OF ALZHEIMERS DISEASE

Mitochondrial Amyloid-β Levels are Associated with the Extent of Mitochondrial Dysfunction in Different Brain Regions and the Degree of Cognitive Impairment in Alzheimer's Transgenic Mice

(2017) Natasa Dragicevic et al.   JOURNAL OF ALZHEIMERS DISEASE

Protective effect of curcumin (Curcuma longa) againstd-galactose-induced senescence in mice

(2011) Anil Kumar et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice

(2011) Johannes Attems et al.   JOURNAL OF NEURAL TRANSMISSION

Mitochondrial response to controlled nutrition in health and disease

(2011) Manuel Schiff et al.   NUTRITION REVIEWS

Severe X-Linked Mitochondrial Encephalomyopathy Associated with a Mutation in Apoptosis-Inducing Factor

(2010) Daniele Ghezzi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Linking Molecules to Mood: New Insight Into the Biology of Depression

(2010) Vaishnav Krishnan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Neuroprotective mechanisms of brain-derived neurotrophic factor against 3-nitropropionic acid toxicity: therapeutic implications for Huntington's disease

(2010) Chia-Lin Wu et al.   Annals of the New York Academy of Sciences

The role of mitochondrial dysfunction in psychiatric disease

(2010) Fernando Scaglia   Developmental Disabilities Research Reviews

Complex I: Inhibitors, inhibition and neurodegeneration

(2010) A.H.V. Schapira   EXPERIMENTAL NEUROLOGY

Mutant SOD1 and mitochondrial damage alter expression and splicing of genes controlling neuritogenesis in models of neurodegeneration

(2010) Silvia C. Lenzken et al.   HUMAN MUTATION

Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis

(2010) Nichole A. Reyes et al.   JOURNAL OF CLINICAL INVESTIGATION

L-3-n-Butylphthalide Improves Cognitive Impairment and Reduces Amyloid-  in a Transgenic Model of Alzheimer's Disease

(2010) Y. Peng et al.   JOURNAL OF NEUROSCIENCE

Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice

(2010) Y.-F. Xu et al.   JOURNAL OF NEUROSCIENCE

Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS

(2010) Adrian Israelson et al.   NEURON

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

Mechanisms of rotenone-induced proteasome inhibition

(2010) Arthur P. Chou et al.   NEUROTOXICOLOGY

Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice

(2010) X. Shan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome

(2010) A. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autoantibodies reacting with vasopressin and oxytocin in relation to cortisol secretion in mild and moderate depression

(2010) Frederico Duarte Garcia et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Molecular pathogenesis of Parkinson disease: insights from genetic studies

(2009) Thomas Gasser   EXPERT REVIEWS IN MOLECULAR MEDICINE

Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis

(2009) Lana Kupershmidt et al.   FASEB JOURNAL

MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease

(2009) D. Galter et al.   GENES BRAIN AND BEHAVIOR

The interplay between mitochondrial complex I, dopamine and Sp1 in schizophrenia

(2009) Dorit Ben-Shachar   JOURNAL OF NEURAL TRANSMISSION

Combination therapy with Coenzyme Q10and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases

(2009) Lichuan Yang et al.   JOURNAL OF NEUROCHEMISTRY

NDUFS4: Creation of a mouse model mimicking a Complex I disorder

(2009) Christopher A. Ingraham et al.   MITOCHONDRION

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Regional brain metabolism with cytochrome c oxidase histochemistry in a PS1/A246E mouse model of autosomal dominant Alzheimer's disease: Correlations with behavior and oxidative stress

(2009) Catherine Strazielle et al.   NEUROCHEMISTRY INTERNATIONAL

Stereotaxical Infusion of Rotenone: A Reliable Rodent Model for Parkinson's Disease

(2009) Nian Xiong et al.   PLoS One

Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants☆

(2008) Ana Navarro et al.   ADVANCED DRUG DELIVERY REVIEWS

Behavioral alterations in rotenone model of Parkinson's disease: Attenuation by co-treatment of centrophenoxine

(2008) Bimla Nehru et al.   BRAIN RESEARCH

Mice with Mitochondrial Complex I Deficiency Develop a Fatal Encephalomyopathy

(2008) Shane E. Kruse et al.   Cell Metabolism

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease

(2008) Rosa Resende et al.   FREE RADICAL BIOLOGY AND MEDICINE

Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease

(2008) Terence Y.C. Pang et al.   HUMAN MOLECULAR GENETICS

Brain mitochondrial dysfunction in aging

(2008) Alberto Boveris et al.   IUBMB LIFE

Comparison of neuroprotective and neurorestorative capabilities of rasagiline and selegiline against lactacystin-induced nigrostriatal dopaminergic degeneration

(2008) Wen Zhu et al.   JOURNAL OF NEUROCHEMISTRY

Loss of Apoptosis-Inducing Factor Results in Cell-Type-Specific Neurogenesis Defects

(2008) R. Ishimura et al.   JOURNAL OF NEUROSCIENCE

Creatine and Its Potential Therapeutic Value for Targeting Cellular Energy Impairment in Neurodegenerative Diseases

(2008) Peter J. Adhihetty et al.   NEUROMOLECULAR MEDICINE

Eat Less, Live Longer? New Insights Into the Role of Caloric Restriction in the Brain

(2008) Cathy W. Levenson et al.   NUTRITION REVIEWS

The Variability of the Harlequin Mouse Phenotype Resembles that of Human Mitochondrial-Complex I-Deficiency Syndromes

(2008) Paule Bénit et al.   PLoS One

Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat

(2008) W.-S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lithium delays progression of amyotrophic lateral sclerosis

(2008) F. Fornai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA