Verapamil, and Its Metabolite Norverapamil, Inhibit Macrophage-induced, Bacterial Efflux Pump-mediated Tolerance to Multiple Anti-tubercular Drugs

Acceleration of Tuberculosis Treatment by Adjunctive Therapy with Verapamil as an Efflux Inhibitor

(2013) Shashank Gupta et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Efflux Inhibition with Verapamil Potentiates Bedaquiline in Mycobacterium tuberculosis

(2013) Shashank Gupta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis

(2012) Diana Machado et al.   PLoS One

Rifampicin Reduces Susceptibility to Ofloxacin in Rifampicin-resistantMycobacterium tuberculosisthrough Efflux

(2011) Gail E. Louw et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism

(2011) Kristin N. Adams et al.   CELL

Rv1218c, an ABC Transporter of Mycobacterium tuberculosis with Implications in Drug Discovery

(2010) M. Balganesh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!

(2010) Leonard Amaral et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis

(2010) S. Sharma et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A Mycobacterium tuberculosis Sigma Factor Network Responds to Cell-Envelope Damage by the Promising Anti-Mycobacterial Thioridazine

(2010) Noton K. Dutta et al.   PLoS One

Bactericidal activity of the diarylquinoline TMC207 against Mycobacterium tuberculosis outside and within cells

(2010) Jasvir Dhillon et al.   TUBERCULOSIS

Substitution of Moxifloxacin for Isoniazid during Intensive Phase Treatment of Pulmonary Tuberculosis

(2009) Susan E. Dorman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sterilizing Activity of R207910 (TMC207)-containing Regimens in the Murine Model of Tuberculosis

(2009) Murad Ibrahim et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Shortening Treatment in Adults with Noncavitary Tuberculosis and 2-Month Culture Conversion

(2009) John L. Johnson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Balancing Act: Efflux/Influx in Mycobacterial Drug Resistance

(2009) G. E. Louw et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efflux-Mediated Drug Resistance in Bacteria

(2009) Xian-Zhi Li et al.   DRUGS

Verapamil for Cluster Headache. Clinical Pharmacology and Possible Mode of Action

(2009) Peer Tfelt-Hansen et al.   HEADACHE

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

(2009) Clifton E. Barry et al.   NATURE REVIEWS MICROBIOLOGY

The Diarylquinoline TMC207 for Multidrug-Resistant Tuberculosis

(2009) Andreas H. Diacon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of Mutations Related to Streptomycin Resistance in Clinical Isolates of Mycobacterium tuberculosis and Possible Involvement of Efflux Mechanism

(2008) F. S. Spies et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Diarylquinolines Are Bactericidal for Dormant Mycobacteria as a Result of Disturbed ATP Homeostasis

(2008) Anil Koul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY