Identification of Collagenase as a Critical Virulence Factor for Invasiveness and Transmission of Pathogenic Leptospira Species

The mammalian cell entry (Mce) protein of pathogenic Leptospira species is responsible for RGD motif-dependent infection of cells and animals

(2012) Lei Zhang et al.   MOLECULAR MICROBIOLOGY

Leptospiral Hemolysins Induce Proinflammatory Cytokines through Toll-Like Receptor 2-and 4-Mediated JNK and NF-κB Signaling Pathways

(2012) Huan Wang et al.   PLoS One

Characterization of Conserved Combined T and B Cell Epitopes in Leptospira interrogans Major Outer Membrane Proteins OmpL1 and LipL41

(2011) Xu'ai Lin et al.   BMC MICROBIOLOGY

Europe's neglected infections of poverty

(2011) Peter J. Hotez et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Leptospirosis prevalence in Chinese populations in the last two decades

(2011) Chenglin Zhang et al.   MICROBES AND INFECTION

Responses of Human Endothelial Cells to Pathogenic and Non-Pathogenic Leptospira Species

(2010) Denise G. Martinez-Lopez et al.   PLoS Neglected Tropical Diseases

A universal strategy for high-yield production of soluble and functional clostridial collagenases in E. coli

(2009) Paulina Ducka et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Leptospirosis research: fast, easy and reliable enumeration of mobile leptospires

(2009) STEFAN SCHREIER et al.   BIOLOGICAL RESEARCH

Inactivation of the fliY gene encoding a flagellar motor switch protein attenuates mobility and virulence of Leptospira interrogans strain Lai

(2009) Sumei Liao et al.   BMC MICROBIOLOGY

Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin

(2009) Shijun Li et al.   Innate Immunity

Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen

(2009) Albert I. Ko et al.   NATURE REVIEWS MICROBIOLOGY

Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity

(2009) Dongjiao Luo et al.   VACCINE

Leptospira and leptospirosis

(2009) Ben Adler et al.   VETERINARY MICROBIOLOGY

Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein

(2008) Haiyan Dong et al.   BMC MICROBIOLOGY

Pathogenic potential of a collagenase gene from Aeromonas veronii

(2008) Hyun-Ja Han et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Selection of the Internal Control Gene for Real-Time Quantitative RT-PCR Assays in Temperature Treated Leptospira

(2008) Erika Margarita Carrillo-Casas et al.   CURRENT MICROBIOLOGY

Differential gene expression and extracellular secretion of the collagenolytic enzymes by the pathogen Vibrio parahaemolyticus

(2008) Shin-ichi Miyoshi et al.   FEMS MICROBIOLOGY LETTERS

Leptospira interrogans Induces Apoptosis in Macrophages via Caspase-8- and Caspase-3-Dependent Pathways

(2008) D. Jin et al.   INFECTION AND IMMUNITY

Leptospirosis: an emerging global public health problem

(2008) P. Vijayachari et al.   JOURNAL OF BIOSCIENCES

Evolution and pathogenesis of Leptospira spp.: lessons learned from the genomes

(2008) Feng Xue et al.   MICROBES AND INFECTION

Genome Sequence of the Saprophyte Leptospira biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis

(2008) Mathieu Picardeau et al.   PLoS One