Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug

A Chemical Genomic Analysis of Decoquinate, aPlasmodium falciparumCytochromebInhibitor

(2011) Tae-gyu Nam et al.   ACS Chemical Biology

A High-Throughput Screen Targeting Malaria Transmission Stages Opens New Avenues for Drug Development

(2011) Kathrin Buchholz et al.   JOURNAL OF INFECTIOUS DISEASES

Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

(2011) N. Klonis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets

(2011) J. Yuan et al.   SCIENCE

A toolbox to study liver stage malaria

(2011) Miguel Prudêncio et al.   TRENDS IN PARASITOLOGY

Inhibiting Plasmodium cytochrome bc1: a complex issue

(2010) Victoria Barton et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Thousands of chemical starting points for antimalarial lead identification

(2010) Francisco-Javier Gamo et al.   NATURE

Chemical genetics of Plasmodium falciparum

(2010) W. Armand Guiguemde et al.   NATURE

Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria elimination

(2010) Timothy N.C. Wells et al.   TRENDS IN PARASITOLOGY

Colorimetric High-Throughput Screen for Detection of Heme Crystallization Inhibitors

(2009) M. A. Rush et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Design, synthesis and structure–activity relationships of (1H-pyridin-4-ylidene)amines as potential antimalarials

(2009) Tiago Rodrigues et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A pre-emptive strike against malaria's stealthy hepatic forms

(2009) Dominique Mazier et al.   NATURE REVIEWS DRUG DISCOVERY

Visualisation and Quantitative Analysis of the Rodent Malaria Liver Stage by Real Time Imaging

(2009) Ivo H. J. Ploemen et al.   PLoS One

Host Scavenger Receptor SR-BI Plays a Dual Role in the Establishment of Malaria Parasite Liver Infection

(2008) Cristina D. Rodrigues et al.   Cell Host & Microbe

Primaquine revisited six decades after its discovery

(2008) Nuno Vale et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure of Complex III with Bound Cytochromecin Reduced State and Definition of a Minimal Core Interface for Electron Transfer

(2008) Sozanne R. N. Solmaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinome-Wide RNAi Screen Implicates at Least 5 Host Hepatocyte Kinases in Plasmodium Sporozoite Infection

(2008) Miguel Prudêncio et al.   PLoS Pathogens