Article
Public, Environmental & Occupational Health
Stephen Chacko, Mushtofa Kamal, Endang Budi Hastuti, Fristika Mildya, Cornelia Kelyombar, Vivi Voronika, Prima Yosephine, Gertrudis Tandy, Devi Anisiska, Sherli Karolina, Lulu Ariyantheny Dewi, Sudhir Khanal, Sunil Bahl, Fetty Wijayanti, Rebecca D. Merrill, Christopher H. Hsu, Michelle Morales
Summary: This report describes the progress made by Indonesia in measles and rubella elimination from 2013 to 2022. While there have been improvements in population coverage, the recent surge in cases can be attributed to the disruption of immunization services caused by the COVID-19 pandemic. Urgent efforts are needed to restore and improve immunization services.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2023)
Article
Immunology
Paul A. Gastanaduy, James L. Goodson, Lakshmi Panagiotakopoulos, Paul A. Rota, Walt A. Orenstein, Manisha Patel
Summary: The global measles vaccination program has been successful in reducing measles-related diseases and deaths worldwide. Routine immunization with measles-containing vaccines has significantly decreased measles incidence and mortality globally. However, the recent global measles resurgence highlights the importance of maintaining high vaccination coverage and strengthening efforts to achieve measles elimination.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Anna A. Minta, Matt Ferrari, Sebastien Antoni, Allison Portnoy, Alyssa Sbarra, Brian Lambert, Cynthia Hatcher, Christopher H. Hsu, Lee Lee Ho, Claudia Steulet, Marta Gacic-Dobo, Paul A. Rota, Mick N. Mulders, Anindya Sekhar Bose, William Perea Caro, Patrick O'Connor, Natasha S. Crowcroft
Summary: This report describes the progress of measles elimination from 2000 to 2022. Although there has been an improvement in measles vaccination coverage globally, the COVID-19 pandemic caused a decline in coverage in 2021, reaching the lowest level since 2008. In 2022, there was a recovery in measles vaccination coverage, but about half of the countries did not achieve the measles surveillance target. The number of measles cases and deaths increased during 2021-2022. Urgent measures are needed to restore vaccination coverage and accelerate measles elimination.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2023)
Article
Public, Environmental & Occupational Health
Laura A. Zimmerman, Ennifer K. Knapp, Sebastien Antoni, Gavin B. Grant, Susan E. Reef
Summary: By 2020, 173 out of 194 countries (89%) had introduced rubella-containing vaccines (RCVs), and 93 (48%) had been verified as having eliminated rubella transmission. While vaccination introduction equity improved significantly among lower income countries, there is still concern about vaccination coverage.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2022)
Review
Public, Environmental & Occupational Health
Mateusz Hasso-Agopsowicz, Natasha Crowcroft, Robin Biellik, Christopher J. Gregory, Marion Menozzi-Arnaud, Jean-Pierre Amorij, Philippe-Alexandre Gilbert, Kristen Earle, Collrane Frivold, Courtney Jarrahian, Mercy Mvundura, Jessica J. Mistilis, David N. Durrheim, Birgitte Giersing
Summary: Measles and rubella microarray patches (MR-MAPs) are crucial for eradicating measles and rubella, but it is unlikely for them to be prequalified by the WHO and ready for use before 2033 due to various limitations. This article discusses the progress, challenges, and opportunities associated with MR-MAPs manufacturing, regulatory approval, demand creation, and licensure timelines. It also highlights ongoing efforts by multiple partners to incentivize investment and expedite the development of MR-MAPs.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Balcha G. Masresha, Cynthia Hatcher, Emmaculate Lebo, Patricia Tanifum, Ado M. Bwaka, Anna A. Minta, Sebastien Antoni, Gavin B. Grant, Robert T. Perry, Patrick O'Connor
Summary: Measles remains a significant health issue globally, especially in the African region. Despite some progress in vaccination, there are still challenges in surveillance performance and vaccine coverage, leading to an increase in measles incidence and deaths.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2023)
Article
Infectious Diseases
Anna Glynn-Robinson, Jennifer K. Knapp, David N. Durrheim
Summary: This study describes the impact of Australia's immunization program and enhanced measles immunization activities on rubella incidence and elimination. Using MMR vaccines to address measles immunity gaps had the additional benefit of controlling rubella in Australia.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Hana Saffar, Maryam Khalifeloo, Mohammad-Jafar Saffar, Alireza Abdollahi, Mohammad-Reza Parsaei, Gholam-Reza Ghorbani, Samaneh Salarvand, Mohsen Aarabi
Summary: Despite high vaccination coverage in Iran, a significant number of vaccinated individuals were found to be seronegative for measles and rubella antibodies, potentially due to secondary vaccine failure. This may negatively impact the country's measles-rubella elimination targets.
BMC INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Ann Levin, Colleen Burgess, Stephanie Shendale, Winthrop Morgan, Raymond Cw Hutubessy, Mark Jit
Summary: The incidence of measles and rubella has declined as vaccine coverage increased. This study assessed the cost-effectiveness of increasing vaccination coverage to eliminate transmission. The most cost-effective scenario was the most accelerated one.
Article
Public, Environmental & Occupational Health
Amy K. Winter, Brian Lambert, Daniel Klein, Petra Klepac, Timos Papadopoulos, Shaun Truelove, Colleen Burgess, Heather Santos, Jennifer K. Knapp, Susan E. Reef, Lidia K. Kayembe, Stephanie Shendale, Katrina Kretsinger, Justin Lessler, Emilia Vynnycky, Kevin McCarthy, Matthew Ferrari, Mark Jit
Summary: The study modeled the potential for global elimination of measles and rubella under different vaccination scenarios. It found that intensified investment can lead to significant reductions in incidence and burden of measles and rubella. Rubella elimination is likely achievable in all countries, but measles elimination is only likely in some countries. Inequity in routine vaccination coverage was identified as a likely driver of continued endemic measles transmission in certain countries.
LANCET GLOBAL HEALTH
(2022)
Article
Immunology
Xiali Yu, Luodan Suo, Wei Li, Weixin Chen, Dan Zhao, Jingbin Pan, Li Lu, Xiaoqun Mu, Fang Huang, Meng Chen, Zhen Zhu
Summary: This study analyzed the progress and challenges towards rubella elimination in Beijing, China, and found that although there has been a downward trend in rubella incidence, there are still challenges such as age-specific concentration and increased viral heterogeneity. The study recommends maintaining routine immunization, promoting regular supplementary immunization activities, and optimizing existing immunization strategies.
Article
Instruments & Instrumentation
James L. Goodson, Paul A. Rota
Summary: Disease eradication and elimination programs require innovations for progress. The complex logistics and drawbacks of current vaccine delivery methods create barriers to vaccination, thus requiring innovative methods for easier, more efficient, and safer vaccine delivery. Microarray patches (MAPs) are recognized as a potential new tool for enhancing global immunizations efforts.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2022)
Article
Immunology
Santosh Kumar Verma, Dheeraj Shah, Aaradhana Singh, Praveen Kumar Singh, Shukla Das, Piyush Gupta
Summary: This study aimed to assess the immunogenicity of measles-rubella (MR) vaccine in Indian children below one year of age. The results showed that the MR vaccine administered under India's Universal Immunization Programme resulted in a high level of seroprotection against rubella and measles. The seroprotection rates for rubella were 97.5% and 100%, and for measles were 88.7% and 100% after the first and second doses, respectively.
INDIAN JOURNAL OF MEDICAL RESEARCH
(2023)
Review
Biology
Andrea J. Lund, Kristen J. Wade, Zachary L. Nikolakis, Kathleen N. Ivey, Blair W. Perry, Hamish N. C. Pike, Sara H. Paull, Yang Liu, Todd A. Castoe, David D. Pollock, Elizabeth J. Carlton
Summary: The global community has set ambitious goals to eliminate schistosomiasis, and new tools, such as whole-genome sequencing, can help tailor interventions and address questions about non-human hosts and the importance of local and imported infections in the elimination process.
Article
Immunology
William J. Moss, Stephanie Shendale, Ann Lindstrand, Atherine L. O'Brien, Nikki Turner, Tracey Goodman, Katrina Kretsinger
Summary: The report discusses the importance, global situation, feasibility, progress and challenges of measles and rubella elimination, as well as the establishment of target dates and proposed frameworks for recommendations endorsed by SAGE.