Article
Materials Science, Textiles
Pelin Altay, Selin Hanife Eryuruk, Gulay Ozcan, Didem Ozturk, Melda Naz Saral, Cagla Altinordu
Summary: The purpose of this study is to reduce heat stress for firefighters by creating a new fabric design with silica aerogel membrane as a moisture barrier for a three-layer fabric system. The results show that the PAN/silica aerogel membrane can be used to create a lighter fabric system with improved thermal comfort properties compared to traditional protective clothing.
INTERNATIONAL JOURNAL OF CLOTHING SCIENCE AND TECHNOLOGY
(2023)
Article
Materials Science, Textiles
Jiaxin Dai, Xiaohui Li
Summary: This study focuses on the performance optimization of honeycomb structure insulation layer. Laser cutting technology was used to prepare insulation layers of different profiles on non-woven fabric, and it was found that the honeycomb fabric system has better thermal protection compared to the conventional solid fabric system. A-type structure showed superior thermal protective performance compared to I-type structure.
JOURNAL OF INDUSTRIAL TEXTILES
(2022)
Article
Materials Science, Textiles
Ah Young Won, Changsang Yun
Summary: The study found that residual detergent and thermal energy contributed to the degradation of flame retardant performance in firefighter clothing, but spin-drying speed and number of rinses did not have an impact. Therefore, to minimize fabric damage, lowering spin-drying speed and reducing exposure to heat are recommended.
FIBERS AND POLYMERS
(2021)
Article
Materials Science, Textiles
Mahipal Meena, Anjlina Kerketta, Manorama Tripathi, Prasun Roy, Josemon Jacob
Summary: In this study, a chemical and biological resistant waterproof breathable flame retardant moisture barrier fabric was developed by laminating a biaxially stretched microporous expanded polytetraflouroethylene (ePTFE) membrane with Activated Carbon Fabric. The laminate exhibited excellent waterproofness, breathability, flame resistance, and protection against biological and chemical warfare agents.
JOURNAL OF INDUSTRIAL TEXTILES
(2022)
Article
Engineering, Multidisciplinary
Meredith McQuerry, Elizabeth Easter
Summary: The cleaning practices of U.S. wildland firefighter personal protective clothing are widely unregulated and unknown, which may lead to severe health impacts. Most wildland firefighters do not follow the recommendations of the National Fire Protection Association when cleaning their gear, highlighting the need for practical and feasible standards.
Article
Materials Science, Textiles
Jawad Naeem, Adnan Mazari, Muhammad Salman Naeem, Abher Rasheed, Fayyaz Ahmad, Sheraz Ahmad
Summary: The objective of this study is to investigate the durability of metallic coating for firefighter protective clothing when subjected to different washing cycles. The study found that specimens coated with silver particles showed improved thermal protective performance as compared to uncoated specimens. After five washing cycles, there was a negligible decline in thermal protective performance when exposed to 40 kW/m(2). Bending moment and water vapor resistance properties showed no considerable difference after different washing cycles, confirming the stability of silver coating layers. However, there was a substantial decline in thermal protective performance of silver-coated outer shells on exposure to 40 kW/m(2) after one hundred to five hundred cycles of abrasion.
JOURNAL OF THE TEXTILE INSTITUTE
(2023)
Article
Polymer Science
Sumit Mandal, Ishmam Zahin Chowdhury, Nur-Us-Shafa Mazumder, Robert J. Agnew, Lynn M. Boorady
Summary: This study aims to scientifically investigate the sweat drying performance of different protective fabrics used in high-risk sectors' workers' clothing and explores the effects of wetted area, air flow, and evaporative resistance on drying performance.
Article
Materials Science, Textiles
Hongyang Wang, Junsheng Wang, Bi Zhao, Shengli Hu, Gang Xue, Jianjun Xia
Summary: This study investigated the effects of inclination angle, waterproof grade, and fabric structure of the flame retardant outer layer of firefighting protective clothing on polycyclic aromatic hydrocarbon (PAH) contamination and laundering. Results showed that fabric with a water repellent finish had increased adsorption capacity, and the outer layer absorbed more PAHs at 180 degrees inclination angle. The fabric structure with single layer had strong adsorption capacity and low removal capacity for PAHs.
JOURNAL OF INDUSTRIAL TEXTILES
(2022)
Article
Materials Science, Textiles
Rochak Rathour, Apurba Das, Ramasamy Alagirusamy
Summary: This study investigates the effect of basic construction parameters of woven fabric on its thermal protection and comfort performance. The researchers found that honeycomb weave has excellent thermal protective performance compared to other weaves, and reducing the ply of yarn decreases the thermal protective performance and areal density of the fabric.
JOURNAL OF THE TEXTILE INSTITUTE
(2023)
Article
Thermodynamics
Jiazhen He, Yehu Lu, Si Chen, Jia Lv
Summary: Thermal protective clothing can have a dual impact on human skin, both resisting heat transfer and causing thermal hazard through stored energy discharge. The size and position of the air gap in clothing affect the heat protective performance and thermal-hazardous performance.
CASE STUDIES IN THERMAL ENGINEERING
(2021)
Article
Environmental Sciences
Kalev Kuklane, Jakob Eggeling, Maurice Kemmeren, Ronald Heus
Summary: Investigators received notifications about the association between first-degree burns and reflective striping and impermeable clothing elements, but the mechanism behind this phenomenon remains unclear. Material tests showed a reduction in heat loss capacity under impermeable elements from dry to wet conditions. Reflective surfaces exhibited lower heat transmission than materials without striping under tested moisture and radiation combinations. Burns may be related to clothing design and tightness/fit rather than reflective striping.
Article
Biophysics
Agnes Psikuta, Fawzy Sherif, Emel Mert, Sumit Mandal, Simon Annaheim
Summary: This study used 3D body scanning technology to investigate the differences in air layer distribution in firefighters' clothing in different postures, and found that body posture significantly affects the thermal performance of the clothing. Therefore, body posture should be considered in the evaluation of clothing protective performance, and improvements should be made based on the clothing properties in real-life exposure.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2023)
Article
Engineering, Civil
S. Krzeminska, M. Szewczynska
Summary: The concentration of polycyclic aromatic hydrocarbons (PAHs) in firefighter protective clothing was determined under different conditions. The study found that the total PAH concentration was strongly dependent on use conditions and clothing layer. PAH concentration was approximately 10-12 times higher in clothing worn during fire suppression compared to clothing worn during live-fire simulation.
FIRE SAFETY JOURNAL
(2022)
Article
Materials Science, Textiles
Jeong-Hwa Park, Tae-Hee Park, Tae-Sun Kim, Jin-Suk Kwon
Summary: This study proposes a method to improve the heat protection performance of firefighter protective clothing lining and investigates the effects of different weaving methods on the protective performance against flame and radiant heat. The results show that the knitted lining exhibits excellent protection performance with delayed temperature increase, outperforming the fabric lining.
TEXTILE RESEARCH JOURNAL
(2023)
Article
Ergonomics
Yun Su, Miao Tian, Xianghui Zhang, Jun Li, Xiaoyu Han
Summary: The study examined moisture distribution and transfer in firefighter protective clothing under exposure to thermal radiation. The results showed that moisture transfer in the clothing was a two-way transmission during both dry heat and wet heat exposures. Understanding moisture transfer can improve thermal protection and reduce steam burns.
INTERNATIONAL JOURNAL OF OCCUPATIONAL SAFETY AND ERGONOMICS
(2022)
Article
Cell Biology
Menglu Gao, Yili Liu, Mingquan Guo, Qianying Wang, Yan Wang, Jian Fan, Yinzhong Shen, Junjie Hou, Yanmin Wan, Zhaoqin Zhu
Summary: The study found that frequencies of lymphocytes and T cells decreased significantly in COVID-19 patients, while the CD4(+)/CD8(+)T cell ratios increased significantly in patients over 45 years old. Regulatory CD4(+) and CD8(+) T cells may play distinct roles in the pathogenesis of COVID-19, and NK cells might contribute to the lymphopenia associated with COVID-19.
JOURNAL OF LEUKOCYTE BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Yili Liu, Daihong Chen, Junjie Hou, Haicong Li, Dan Cao, Mingquan Guo, Yun Ling, Menglu Gao, Yi Zhou, Yanmin Wan, Zhaoqin Zhu
Summary: Elevated plasma levels of IL-6, IL-8, and IL-5 were consistently found in deceased COVID-19 patients compared to those with mild/moderate or severe disease. The early plasma concentrations of IFN-a and IL-2 positively correlated with the length of the disease course. IL-6, IL-8, and IL-5 may play central roles in cytokine storms associated with COVID-19.
Article
Virology
Xiangqing Ding, Kangli Cao, Jing Wang, Yanmin Wan, Qinyun Chen, Yanqin Ren, Yongtang Zheng, Mingzhao Zhu, Renrong Tian, Wenjun Wang, Chen Zhao, Xiaoyan Zhang, Jianqing Xu
Summary: The study explored the utility of diverse HIV-1 envelope immunogens in a sequential immunization scheme to raise a heterologous tier 2 nAb response for HIV vaccine development. By implementing a three-immunization regimen in rhesus macaque over a short 8-week schedule, a potent nAb response with substantial breadth was elicited, effectively containing viremia upon a heterologous SHIV challenge. This highlights the potential of diversifying Env immunogens under a sequential immunization scheme for HIV vaccine development.
Article
Immunology
Yin Yao, Zhian Chen, Hao Zhang, Cailing Chen, Ming Zeng, Joseph Yunis, Yunbo Wei, Yanmin Wan, Naiqi Wang, Mingzhe Zhou, Chao Qiu, Qunxiong Zeng, Hong Sheng Ong, Hao Wang, Fadzai Victor Makota, Yang Yang, Zhaohui Yang, Nan Wang, Jun Deng, Chao Shen, Yan Xia, Lin Yuan, Zhaoqin Lian, Yike Deng, Cuilian Guo, Ao Huang, Pengcheng Zhou, Haibo Shi, Weitian Zhang, Hongliang Yi, Dongmei Li, Ming Xia, Jing Fu, Ning Wu, Judy B. de Haan, Nan Shen, Wenhong Zhang, Zheng Liu, Di Yu
Summary: Researchers found that T follicular helper (T-FH) cells are highly sensitive to ferroptosis, and this process is regulated by the activity of the selenoenzyme GPX4. Selenium supplementation can increase GPX4 expression, leading to an increase in T-FH cell numbers and antibody responses.
Article
Multidisciplinary Sciences
Jun Deng, Qian Chen, Zhian Chen, Kaili Liang, Xin Gao, Xiaohui Wang, Fadzai Makota, Hong Sheng Ong, Yanmin Wan, Kaiming Luo, Dongcheng Gong, Xiang Yu, Sarina Camuglia, Qunxiong Zeng, Tao Zhou, Feng Xue, Jing He, Yunbo Wei, Fan Xiao, Jianyang Ma, Danika L. Hill, Wim Pierson, Thi H. O. Nguyen, Haibo Zhou, Yan Wang, Wei Shen, Lingyun Sun, Zhanguo Li, Qiang Xia, Kun Qian, Lilin Ye, Steven Rockman, Michelle A. Linterman, Katherine Kedzierska, Nan Shen, Liwei Lu, Di Yu
Summary: Leptin levels are associated with reduced vaccine responses, as it promotes T-FH differentiation and IL-21 production. Leptin deficiency impairs T-FH generation and antibody responses, increasing the risk of vaccine failure.
NATURE COMMUNICATIONS
(2021)
Article
Cell Biology
Zhidan Li, Wei Zhang, Fang Luo, Jian Li, Wenbin Yang, Bingkuan Zhu, Qunfeng Wu, Xiaoling Wang, Chengsong Sun, Yuxiang Xie, Bin Xu, Zhaojun Wang, Feng Qian, Jiaxu Chen, Yanmin Wan, Wei Hu
Summary: Lung-stage Schistosoma japonicum infection protects against OVA-induced asthma by upregulating Treg cells in lung tissue to suppress IgE production.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Correction
Immunology
Yin Yao, Zhian Chen, Hao Zhang, Cailing Chen, Ming Zeng, Joseph Yunis, Yunbo Wei, Yanmin Wan, Naiqi Wang, Mingzhe Zhou, Chao Qiu, Qunxiong Zeng, Hong Sheng Ong, Hao Wang, Fadzai Victor Makota, Yang Yang, Zhaohui Yang, Nan Wang, Jun Deng, Chao Shen, Yan Xia, Lin Yuan, Zhaoqin Lian, Yike Deng, Cuilian Guo, Ao Huang, Pengcheng Zhou, Haibo Shi, Weitian Zhang, Hongliang Yi, Dongmei Li, Ming Xia, Jing Fu, Ning Wu, Judy B. de Haan, Nan Shen, Wenhong Zhang, Zheng Liu, Di Yu
Article
Immunology
Jingwen Ai, Haocheng Zhang, Yi Zhang, Ke Lin, Yanliang Zhang, Jing Wu, Yanming Wan, Yanfang Huang, Jieyu Song, Zhangfan Fu, Hongyu Wang, Jingxin Guo, Ning Jiang, Mingxiang Fan, Yang Zhou, Yuanhan Zhao, Qiran Zhang, Qiang Liu, Jing Lv, Peiyao Li, Chao Qiu, Wenhong Zhang
Summary: This study explored the immunogenicity of different vaccination strategies against the Omicron variant of SARS-CoV-2. The results showed that the Omicron variant has a high immune escape ability compared to other variants, but heterologous protein subunit vaccines and homologous inactivated vaccine boosters can improve neutralization against Omicron.
EMERGING MICROBES & INFECTIONS
(2022)
Review
Virology
Shaoshuai Li, Yang Zhou, Dongmei Yan, Yanmin Wan
Summary: The gut microbiota and COVID-19 have a mutual impact on each other. COVID-19 can affect the composition of the gut microbiota, and changes in the gut microbiota may be related to the severity of COVID-19. Additionally, there is immune cross-reactivity between SARS-CoV-2 and commensal bacteria.
Article
Immunology
Xuyang Wang, Liqiu Jia, Yang Liu, Jing Wang, Chao Qiu, Tao Li, Wenhong Zhang, Zhaoqin Zhu, Jing Wu, Yanmin Wan
Summary: Individuals with IL12RB1 deficiency are more susceptible to BCG and environmental mycobacteria infections. This study using a mouse model reveals that IL12RB1-deficient mice have impaired tuberculosis suppression, with decreased innate immune responses and increased IL-17 responses. It suggests that IFN-gamma responses alone may not be sufficient to contain BCG infection in the setting of IL12RB1 deficiency.
Article
Virology
Xuyang Wang, Yumeng Zhang, Yinyin Ben, Chao Qiu, Jing Wu, Wenhong Zhang, Yanmin Wan
Summary: This study reveals a negative correlation between anti-HBc IgG responses in early HBV infection and virus replication, and demonstrates the inhibitory effect of anti-HBc antibodies on virus replication. This finding has significant implications for immunotherapy against hepatitis B.
Article
Medicine, General & Internal
Yanmeng Feng, Yifan Zhang, Shengya Liu, Meng Guo, Haojie Huang, Cuiyuan Guo, Wanhai Wang, Wenhong Zhang, Heng Tang, Yanmin Wan
Summary: This study compared the antibody responses against monkeypox virus (MPXV) and vaccinia virus in cohorts of gay men and the general adult population. It found that individuals born in/after 1981 in the gay men cohort had lower antibody responses against MPXV but higher neutralizing antibody responses against vaccinia compared to the general population. These findings provide insights into the impact of preexisting antibodies on MPXV transmission in the MSM community.
Letter
Biochemistry & Molecular Biology
Qiao-ling Ruan, Zhi-chao Wang, Cheng-jiang Wei, Wei Wang, Qing-luan Yang, Jing Wu, Yan-min Wan, Ling-ling Ge, Wen-hong Zhang, Qing-feng Li
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2023)
Article
Medicine, General & Internal
Yanmeng Feng, Yifan Zhang, Zhangyufan He, Haojie Huang, Xiangxiang Tian, Gang Wang, Daihong Chen, Yanqin Ren, Liqiu Jia, Wanhai Wang, Jing Wu, Lingyun Shao, Wenhong Zhang, Heng Tang, Yanmin Wan
Summary: In this study, it was found that the inactivated COVID-19 vaccine was safe and immunogenic in HIV-1 infected individuals who are stable on cART. Participants did not experience significant adverse reactions after vaccination. Interestingly, HIV-infected individuals with low baseline CD4(+)/CD8(+) T cell ratios exhibited lower antibody responses post-vaccination compared to those with higher ratios.
Article
Immunology
Min Xie, Joseph Yunis, Yin Yao, Jing Shi, Yang Yang, Pengcheng Zhou, Kaili Liang, Yanmin Wan, Ahmed Mehdi, Zhian Chen, Naiqi Wang, Shuyun Xu, Min Zhou, Muqing Yu, Ke Wang, Yu Tao, Ying Zhou, Xiaochen Li, Xiansheng Liu, Xiao Yu, Yunbo Wei, Zheng Liu, Jonathan Sprent, Di Yu
Summary: The study aimed to understand the immune response in COVID-19 patients with T cells showing both functional defects and hyperactivation. Elevated levels of sCD25 were found in severe cases, indicating insufficient anti-viral immunity and expansion of pro-inflammatory T cells. The mouse model and clinical observation confirmed the association between high sCD25 levels and disease severity.
CLINICAL & TRANSLATIONAL IMMUNOLOGY
(2021)
