Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways

An Enzymatic Pathway for the Biosynthesis of the Formylhydroxyornithine Required for Rhodochelin Iron Coordination

(2012) Mattia Bosello et al.   BIOCHEMISTRY

Biochemical and Structural Characterization of Germicidin Synthase: Analysis of a Type III Polyketide Synthase That Employs Acyl-ACP as a Starter Unit Donor

(2012) Joseph A. Chemler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure and biosynthesis of the unusual polyketide alkaloid coelimycin P1, a metabolic product of the cpk gene cluster of Streptomyces coelicolor M145

(2012) Juan Pablo Gomez-Escribano et al.   Chemical Science

Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway inStreptomyces coelicolor

(2011) Jonathan R. Whicher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regio- and stereodivergent antibiotic oxidative carbocyclizations catalysed by Rieske oxygenase-like enzymes

(2011) Paulina K. Sydor et al.   Nature Chemistry

Distinct Extracytoplasmic Siderophore Binding Proteins Recognize Ferrioxamines and Ferricoelichelin inStreptomyces coelicolorA3(2)

(2010) Prakash Patel et al.   BIOCHEMISTRY

A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically 13C-labelled glycerols

(2010) Christophe Corre et al.   CHEMICAL COMMUNICATIONS

Streptomyces coelicolor A3(2) Produces a New Yellow Pigment Associated with the Polyketide Synthase Cpk

(2010) Krzysztof Pawlik et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Stereochemical Elucidation of Streptorubin B

(2010) Stuart W. Haynes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2)

(2010) M. Gottelt et al.   MICROBIOLOGY-SGM

Genomic basis for natural product biosynthetic diversity in the actinomycetes

(2009) Markus Nett et al.   NATURAL PRODUCT REPORTS

Biosynthesis and biosynthetic engineering of calcium-dependent lipopeptide antibiotics

(2009) Jason Micklefield   PURE AND APPLIED CHEMISTRY

Role and substrate specificity of the Streptomyces coelicolor RedH enzyme in undecylprodiginine biosynthesis

(2008) Stuart W. Haynes et al.   CHEMICAL COMMUNICATIONS

Elucidation of the Streptomyces coelicolor Pathway to 2-Undecylpyrrole, a Key Intermediate in Undecylprodiginine and Streptorubin B Biosynthesis

(2008) SangJoon Mo et al.   CHEMISTRY & BIOLOGY

Biosynthesis of the Sesquiterpene Antibiotic Albaflavenone inStreptomyces coelicolorA3(2)

(2008) Bin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phenolic Lipids Synthesized by Type III Polyketide Synthase Confer Penicillin Resistance onStreptomyces griseus

(2008) Masanori Funabashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemistry and Molecular Genetics of the Biosynthesis of the Earthy Odorant Methylisoborneol inStreptomyces coelicolor

(2008) Chieh-Mei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production inStreptomyces coelicolor

(2008) Sean O'Rourke et al.   MOLECULAR MICROBIOLOGY

δ-Amino group hydroxylation of l-ornithine during coelichelin biosynthesis

(2008) Verena Pohlmann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining

(2008) C. Corre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA