Engineering microbial factories for synthesis of value-added products

Genetically Engineered Lipopeptide Antibiotics Related to A54145 and Daptomycin with Improved Properties

(2010) K. T. Nguyen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Heterologous Expression and Extracellular Secretion of Cellulolytic Enzymes by Zymomonas mobilis

(2010) J. G. Linger et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Increased Ethanol Productivity in Xylose-Utilizing Saccharomyces cerevisiae via a Randomly Mutagenized Xylose Reductase

(2010) D. Runquist et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Surface Display of a Functional Minicellulosome by Intracellular Complementation Using a Synthetic Yeast Consortium and Its Application to Cellulose Hydrolysis and Ethanol Production

(2010) S.-L. Tsai et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Functional Genomic Study of Exogenous n-Butanol Stress in Escherichia coli

(2010) B. J. Rutherford et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Escherichia coli Strains Engineered for Homofermentative Production of D-Lactic Acid from Glycerol

(2010) S. Mazumdar et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genetic and metabolic engineering of isoflavonoid biosynthesis

(2010) Hai Du et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineered polyketide biosynthesis and biocatalysis in Escherichia coli

(2010) Xue Gao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Precursor-Directed Biosynthesis of Curcumin Analogs inEscherichia coli

(2010) Yohei KATSUYAMA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for the production of l-threonine

(2010) Xunyan Dong et al.   BIOTECHNOLOGY ADVANCES

A versatile polyacrylamide gel electrophoresis based sulfotransferase assay

(2010) Zhengliang L Wu et al.   BMC BIOTECHNOLOGY

Directed Evolution Toward Improved Production of L-Ribose from Ribitol

(2010) Trevor N. Christ et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

d-(−)-Lactic acid production from cellobiose and cellulose by Lactobacillus lactis mutant RM2-24

(2010) Mamta Singhvi et al.   GREEN CHEMISTRY

Technology development for the production of biobased products from biorefinery carbohydrates—the US Department of Energy’s “Top 10” revisited

(2010) Joseph J. Bozell et al.   GREEN CHEMISTRY

Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions

(2010) Dylan C Alexander et al.   JOURNAL OF ANTIBIOTICS

Programming of Erythromycin Biosynthesis by a Modular Polyketide Synthase

(2010) David E. Cane   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering

(2010) Min-Eui Hong et al.   JOURNAL OF BIOTECHNOLOGY

Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters

(2010) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Strain improvement of the pentose-fermenting yeast Pichia stipitis by genome shuffling

(2010) Paramjit K. Bajwa et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Metabolic engineering of Saccharomyces cerevisiae for the biotechnological production of succinic acid

(2010) Andreas M. Raab et al.   METABOLIC ENGINEERING

Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli

(2010) Tae Seok Moon et al.   METABOLIC ENGINEERING

Selective reduction of xylose to xylitol from a mixture of hemicellulosic sugars

(2010) Nikhil U. Nair et al.   METABOLIC ENGINEERING

Discovery and characterization of novel d-xylose-specific transporters from Neurospora crassa and Pichia stipitis

(2010) Jing Du et al.   Molecular BioSystems

Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis

(2010) Carlos Olano et al.   NATURAL PRODUCT REPORTS

Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

(2010) Eric J. Steen et al.   NATURE

Cellodextrin Transport in Yeast for Improved Biofuel Production

(2010) J. M. Galazka et al.   SCIENCE

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

(2010) D. G. Gibson et al.   SCIENCE

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

(2010) P. K. Ajikumar et al.   SCIENCE

Microbial Biosynthesis of Alkanes

(2010) A. Schirmer et al.   SCIENCE

Yeast Surface Display of Trifunctional Minicellulosomes for Simultaneous Saccharification and Fermentation of Cellulose to Ethanol

(2009) F. Wen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genes Involved in Long-Chain Alkene Biosynthesis in Micrococcus luteus

(2009) H. R. Beller et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microbial Conversion of Glycerol to 1,3-Propanediol by an Engineered Strain of Escherichia coli

(2009) X. Tang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biosynthetic pathways for 3-hydroxypropionic acid production

(2009) Xinglin Jiang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes

(2009) Shota Atsumi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Perspectives and limits of engineering the isoprenoid metabolism in heterologous hosts

(2009) Remco Muntendam et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bioethanol production performance of five recombinant strains of laboratory and industrial xylose-fermenting Saccharomyces cerevisiae

(2009) Akinori Matsushika et al.   BIORESOURCE TECHNOLOGY

Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production inEscherichia coli

(2009) Haoran Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Medicinally important secondary metabolites in recombinant microorganisms or plants: Progress in alkaloid biosynthesis

(2009) Holger Schäfer et al.   Biotechnology Journal

Protein engineering in designing tailored enzymes and microorganisms for biofuels production

(2009) Fei Wen et al.   CURRENT OPINION IN BIOTECHNOLOGY

Bacterial vitamin B2, B11 and B12 overproduction: An overview

(2009) Catherine M. Burgess et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Engineering metabolic systems for production of advanced fuels

(2009) Yajun Yan et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Heterologous production of non-ribosomal peptide LLD-ACV in Saccharomyces cerevisiae

(2009) Verena Siewers et al.   METABOLIC ENGINEERING

Metabolic engineering of Escherichia coli for the biological synthesis of 7-O-xylosyl naringenin

(2009) Dinesh Simkhada et al.   MOLECULES AND CELLS

Antitumor compounds from actinomycetes: from gene clusters to new derivatives by combinatorial biosynthesis

(2009) Carlos Olano et al.   NATURAL PRODUCT REPORTS

Opportunities in metabolic engineering to facilitate scalable alkaloid production

(2009) Effendi Leonard et al.   Nature Chemical Biology

Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential?

(2009) Hal Alper et al.   NATURE REVIEWS MICROBIOLOGY

Efficient Production of L-Ribose with a Recombinant Escherichia coli Biocatalyst

(2008) R. D. Woodyer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Production of Glucaric Acid from a Synthetic Pathway in Recombinant Escherichia coli

(2008) T. S. Moon et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Expression of the Gxf1 transporter from Candida intermedia improves fermentation performance in recombinant xylose-utilizing Saccharomyces cerevisiae

(2008) D. Runquist et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Expression of a heterologous xylose transporter in a Saccharomyces cerevisiae strain engineered to utilize xylose improves aerobic xylose consumption

(2008) Ronald E. Hector et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Current status, strategies, and potential for the metabolic engineering of heterologous polyketides in Escherichia coli

(2008) Brett A. Boghigian et al.   BIOTECHNOLOGY LETTERS

Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid

(2008) Dae-Kyun Ro et al.   BMC BIOTECHNOLOGY

Evolution in Reverse: Engineering a D-Xylose-Specific Xylose Reductase

(2008) Nikhil U. Nair et al.   CHEMBIOCHEM

Metabolic engineering of microorganisms: general strategies and drug production

(2008) Sang Yup Lee et al.   DRUG DISCOVERY TODAY

Improvement of ethanol productivity during xylose and glucose co-fermentation by xylose-assimilating S. cerevisiae via expression of glucose transporter Sut1

(2008) Satoshi Katahira et al.   ENZYME AND MICROBIAL TECHNOLOGY

EngineeredSaccharomyces cerevisiaethat produces 1,3-propanediol from d-glucose

(2008) Z. Rao et al.   JOURNAL OF APPLIED MICROBIOLOGY

Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production

(2008) Benedikt Engels et al.   METABOLIC ENGINEERING

Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol

(2008) Eric J Steen et al.   Microbial Cell Factories

Production of curcuminoids by Escherichia coli carrying an artificial biosynthesis pathway

(2008) Y. Katsuyama et al.   MICROBIOLOGY-SGM

Strain Improvement of RecombinantEscherichia colifor Efficient Production of Plant Flavonoids

(2008) Effendi Leonard et al.   MOLECULAR PHARMACEUTICS

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

(2008) Shota Atsumi et al.   NATURE

How biotech can transform biofuels

(2008) Lee R Lynd et al.   NATURE BIOTECHNOLOGY

Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae

(2008) Kristy M Hawkins et al.   Nature Chemical Biology

DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways

(2008) Zengyi Shao et al.   NUCLEIC ACIDS RESEARCH

Microbial production of plant benzylisoquinoline alkaloids

(2008) H. Minami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome

(2008) D. G. Gibson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli

(2008) W. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

(2008) D. G. Gibson et al.   SCIENCE

Engineering microbes with synthetic biology frameworks

(2008) Effendi Leonard et al.   TRENDS IN BIOTECHNOLOGY

Metabolic engineering of Escherichia coli for 1-butanol production

(2007) Shota Atsumi et al.   METABOLIC ENGINEERING

Efficient Succinic Acid Production from Glucose through Overexpression of Pyruvate Carboxylase in an Escherichia coli Alcohol Dehydrogenase and Lactate Dehydrogenase Mutant

(2005) Ailen M. Sánchez et al.   BIOTECHNOLOGY PROGRESS