Review
Chemistry, Analytical
Akseer Ali Mirani, Gustavo Velasco-Hernandez, Anshul Awasthi, Joseph Walsh
Summary: The Industrial Internet of Things (IIoT) is revolutionizing industrial processes through remote monitoring, intelligent analytics, and control. However, in the early stages of adopting full-stack development solutions with IIoT, there are challenges to address. Researchers have proposed IIoT architectures based on different layers and emerging technologies for end-to-end integration. This paper reviews and compares three widely accepted IIoT reference architectures and presents a state-of-the-art review of conceptual and experimental IIoT architectures from the literature.
Review
Environmental Sciences
Padala Abdul Nishad, Anupkumar Bhaskarapillai
Summary: Technologies for remediation of industrial effluents and natural sources contaminated with antimony are still emerging due to the complexity of antimony speciation. Custom-made treatment methodologies are needed for different sources of antimony pollution, and further research is required to improve antimony removal techniques.
Article
Thermodynamics
Yulong Yan, Junjie Li, Xiaolin Duan, Dong Yang
Summary: This study comprehensively evaluated the environmental impacts of nine industrialized ECCTs in China, with results showing that medium- and low-temperature coal tar hydrogenation, coal to fuel ethanol, coal to ethylene glycol, and coal to olefins had lower environmental impacts. Without mitigation strategies, carbon emissions from the industrialization of ECCTs may significantly increase.
ENERGY CONVERSION AND MANAGEMENT
(2022)
Article
Computer Science, Information Systems
Sudatta Kar, Arpan K. Kar, M. P. Gupta
Summary: The study explores the learning behavior of professionals towards emerging digital technologies in IIoT, finding that factors such as social influence, personal innovativeness, anxiety, long-term consequence, and job relevance affect the intention to learn, with performance level and technology preference moderating this relationship. Exceptional performers are driven by personal innovativeness, while average performers are influenced by social influence and anxiety. Technology maturity and use potential also influence professionals' preference in learning behaviors.
Article
Chemistry, Multidisciplinary
Akira Isogai
Summary: Nanocelluloses have unique morphologies, characteristics, and surface nanostructures, and can be prepared from abundant and renewable plant biomass resources. They have the potential to contribute to the establishment of a sustainable society and help overcome global environmental issues. However, overcoming fundamental and application-related issues is necessary for the further expansion of nanocelluloses.
ADVANCED MATERIALS
(2021)
Review
Genetics & Heredity
Jeffrey R. Moffitt, Emma Lundberg, Holger Heyn
Summary: Improved scale, multiplexing and resolution of spatial nucleic acid and protein profiling methods have established them as a major component of cellular atlas building. These methods enable measurements at nano- to microscale resolutions, allowing the study of cellular heterogeneity, tissue architectures, and dynamic changes during development and disease. This review provides an overview of the emerging landscape of in situ spatial genome, transcriptome, and proteome technologies, highlighting their impact on cell biology and translational research.
NATURE REVIEWS GENETICS
(2022)
Review
Chemistry, Multidisciplinary
Yu Ding, Dong Xing, Yiyan Fei, Boxun Lu
Summary: Targeted protein degradation (TPD) provides unprecedented opportunities for drug discovery. PROTACs technology has already entered clinical trials and changed the landscape of small-molecule drugs. In addition to PROTACs, new degrader technologies harnessing alternative degradation machineries, especially lysosomal pathways, have emerged and broadened the spectrum of degradable targets.
CHEMICAL SOCIETY REVIEWS
(2022)
Article
Green & Sustainable Science & Technology
Matthias Buyle, Ben Maes, Steven Van Passel, Katrien Boonen, An Vercalsteren, Amaryllis Audenaert, Jiri Jaromir Klemes
Summary: In this study, a ex-ante life cycle assessment was used to evaluate a novel technological pathway for extracting chromium from carbon steel slag and valorizing the residual matrix material. The research showed that using simple calculation rules in combination with basic design principles for processes at an industrial scale is more efficient than a fully-fledged process design from the start.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Biochemical Research Methods
Javier Antonio Alfaro, Peggy Bohlander, Mingjie Dai, Mike Filius, Cecil J. Howard, Xander F. van Kooten, Shilo Ohayon, Adam Pomorski, Sonja Schmid, Aleksei Aksimentiev, Eric V. Anslyn, Georges Bedran, Chan Cao, Mauro Chinappi, Etienne Coyaud, Cees Dekker, Gunnar Dittmar, Nicholas Drachman, Rienk Eelkema, David Goodlett, Sebastien Hentz, Umesh Kalathiya, Neil L. Kelleher, Ryan T. Kelly, Zvi Kelman, Sung Hyun Kim, Bernhard Kuster, David Rodriguez-Larrea, Stuart Lindsay, Giovanni Maglia, Edward M. Marcotte, John P. Marino, Christophe Masselon, Michael Mayer, Patroklos Samaras, Kumar Sarthak, Lusia Sepiashvili, Derek Stein, Meni Wanunu, Mathias Wilhelm, Peng Yin, Amit Meller, Chirlmin Joo
Summary: Single-cell profiling methods have greatly impacted the understanding of cellular heterogeneity, although proteome profiling at the single-cell level is still in the early stages. The development of new technologies, such as single-molecule protein sequencing and innovations in mass spectrometry, will eventually enable broad sequence coverage in single-cell proteomics, leading to new biological discoveries and opportunities for ultra-sensitive disease diagnostics.
Review
Chemistry, Multidisciplinary
Hossein Ravanbakhsh, Vahid Karamzadeh, Guangyu Bao, Luc Mongeau, David Juncker, Yu Shrike Zhang
Summary: Bioprinting aims at creating functional biomimetic constructs, and multi-material bioprinting allows for better replication of cellular diversity and tissue complexity, opening up new opportunities for tissue engineering, tissue model engineering, therapeutics development, and personalized medicine.
ADVANCED MATERIALS
(2021)
Review
Engineering, Biomedical
William Y. Song, James L. Robar, Bjorn Moren, Torbjern Larsson, Asa Carlsson Tedgren, Xun Jia
Summary: This article reviews emerging technologies in the field of brachytherapy, including intensity modulated brachytherapy, 3D printing, innovations in treatment planning, and deep learning. The authors believe that these new technologies have the potential to impact future brachytherapy practices.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Gozde Kabay, Jonalyn DeCastro, Alara Altay, Katherine Smith, Hsiang-Wei Lu, Antonia McDonnell Capossela, Maryam Moarefian, Kiana Aran, Can Dincer
Summary: This article discusses the challenges and demands in managing viral infectious diseases, and introduces the latest biosensor technologies. It analyzes their advantages and limitations from a material perspective. The development direction of next-generation biosensing technologies is also explored, along with suggestions for further improvement in managing future pandemics.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Analytical
Chang Liu, Yu Qie, Weiping Qin, Keda Zhao, Jianqiao Zhu, Lixia Zhao, Minjie Li, Liang-Hong Guo
Summary: Exosomes are nano-scale biofilm-enclosed vesicles involved in intercellular communications and seen as potential biomarkers for liquid biopsy. Traditional exosome detection methods have limited sensitivity and specificity, prompting the need for new analytical approaches. Immunoassay-based technologies for rapid exosome detection have gained significant interest recently, offering new possibilities for early disease diagnosis.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Review
Biotechnology & Applied Microbiology
Xin Zhou, Qing Huang, Yang Jiang, Huijing Tang, Luhan Zhang, Danyang Li, Yunsheng Xu
Summary: Extracellular vesicles (EVs) are secreted vesicles that carry biological information and have been studied for diagnostic and therapeutic applications. However, natural EVs have limitations that can be improved through engineering techniques. This review provides an overview of advanced strategies for EV engineering, including pre-treatment of parent cells and direct modification of EVs.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Cell Biology
Hang Luo, Li Wu, Yujian He, Chong Qin, Xinjing Tang
Summary: Proteolysis-targeting chimeras (PROTACs) have emerged as an attractive pharmaceutical development approach with the ability to degrade disease-causing proteins. This review categorizes and emphasizes the molecular design of various emerging PROTACs. In addition, alternatives to PROTACs, such as lysosome-targeting chimeras (LYTACs) and macroautophagy degradation targeting chimeras (MADTACs), are summarized, along with the potential application of targeting RNA degradation.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)