Journal
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
Volume 20, Issue 5, Pages 3046-3052Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jiec.2013.11.041
Keywords
Juncus effusus L.; Cellular protective effect; Dehydroeffusol; Skin-aging; Mechanism
Funding
- Korea Healthcare technology R&D Project, Ministry of Health & Welfare, Republic of Korea [A103017]
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The purpose of this study was to identify the substance responsible for significant cellular protective effect of the extract from Juncus effusus L. on the photohemolysis of erythrocyte and to investigate the mechanism underlying this effect. The single substance was identified as dehydroeffusol. To investigate the mechanism, cellular protective effect, singlet oxygen quenching rate constant, free radical and reactive oxygen species (ROS) scavenging activity and erythrocyte membrane penetration efficiency were tested. The results showed that ROS incidentally produced in the Type II reaction is the main reason for photohemolysis and that erythrocyte membrane penetration ability is crucial to cell protection. (C) 2013 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
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