Journal
ORGANIC LETTERS
Volume 18, Issue 1, Pages 64-67Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b03246
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Funding
- National Institutes of Health (NIGMS) [R01GM110560]
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A variety of substituted indoles and benzofurans are accessed via a platinum catalyzed annulation and vinylogous addition of enol nudeophiles. Several beta-dicarbonyl compounds participate in the reaction, as do alpha-nitro and alpha-cyano carbonyl species. Subjecting the indole products to acidic conditions results in the formation of fused heterocycles.
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