Article
Physiology
Nikolaos Zaras, Angeliki-Nikoletta Stasinaki, Polyxeni Spiliopoulou, Giannis Arnaoutis, Marios Hadjicharalambous, Gerasimos Terzis
Summary: The study found that weightlifting performance improved significantly after a 16-week training period, with leg press RFD increasing in specific time windows while peak force remained unchanged. Some strength indicators showed significant improvements, but muscle architecture and lean body mass did not change significantly.
INTERNATIONAL JOURNAL OF SPORTS PHYSIOLOGY AND PERFORMANCE
(2021)
Letter
Medicine, General & Internal
David A. Gorelick
Summary: This comprehensive review of human adipose tissue fails to mention the role of the endocannabinoid system in fat metabolism. The endogenous cannabinoids and their receptors, found in both white and brown fat, have been recognized as key players in adipose tissue metabolism. Rimonabant, an inverse agonist of cannabinoid receptor type 1, has shown promising effects as a therapeutic target for obesity, dyslipidemia, and insulin resistance, although its clinical use was discontinued due to neuropsychiatric side effects.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Multidisciplinary Sciences
Ingo Sandau, Helmi Chaabene, Urs Granacher
Summary: This study examined the concurrent validity of two different methods for measuring mean vertical barbell force during the snatch. The results showed a high correlation between the methods, but individual differences can lead to errors in force measures.
Article
Multidisciplinary Sciences
Osama Mahmoud, Frank Dudbridge, George Davey Smith, Marcus Munafo, Kate Tilling
Summary: This article presents a method called 'Slope-Hunter' that corrects conditional bias in genetic associations using model-based clustering. The study found that this method eliminates bias and outperforms alternatives even in the presence of genetic correlation.
NATURE COMMUNICATIONS
(2022)
Article
Clinical Neurology
Jinlei Li, Chunyu Liu, Ting Fang Alvin Ang, Rhoda Au
Summary: This study found that decreasing BMI trends in late life were associated with higher risk of developing dementia. Among them, individuals with an initial increase and subsequent decline in BMI during mid-life had a greater risk of dementia.
ALZHEIMERS & DEMENTIA
(2022)
Article
Multidisciplinary Sciences
Glen E. Duncan, Ally Avery, Jennifer L. M. Thorson, Eric E. Nilsson, Daniel Beck, Michael K. Skinner
Summary: An epigenome-wide association study on monozygotic twins revealed that physical activity can promote systemic epigenetic alterations and impact metabolic risk factors. The study analyzed differences in body mass index, physical activity levels, and neighborhood walkability between twin pairs and identified DNA methylation alterations associated with reduced metabolic parameters. The study also identified genes related to vigorous physical activity, metabolic risk factors, and sex.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Indah Suci Widyahening, Dhanasari Vidiawati, Trevino A. Pakasi, Pradana Soewondo, Abdillah Ahsan
Summary: Noncommunicable diseases (NCDs) pose a significant public health challenge in Indonesia, and their risk factors are associated with COVID-19 severity and mortality. This study investigated the NCD risk profile among university employees in Indonesia and its relationship with contracting COVID-19. The findings revealed a high prevalence of NCD risk factors among university administrative employees, which increased their susceptibility to COVID-19. The study highlights the urgent need for a behavioral intervention program to manage NCD risk factors at the university level.
Article
Multidisciplinary Sciences
Praachi Das, Morganne Igoe, Suzanne Lenhart, Lan Luong, Cristina Lanzas, Alun L. Lloyd, Agricola Odoi
Summary: This study investigates the geographic disparities of COVID-19 risk and the associations between COVID-19 risk and socioeconomic, demographic, movement, and chronic disease factors in the Greater St. Louis Area of Missouri. The results show that there are geographic disparities in COVID-19 risk, and these risks are associated with sociodemographic factors, population movements, and obesity hospitalization risks. The findings highlight the importance of considering these factors in controlling and preventing COVID-19.
Article
Sport Sciences
Georgia-Kassandra Kelekian, Nikolaos Zaras, Angeliki-Nikoletta Stasinaki, Polyxeni Spiliopoulou, Giorgos Karampatsos, Gregory Bogdanis, Gerasimos Terzis
Summary: The aim of this study was to investigate the acute effects of performing clean pulls with either 85% or 120% one repetition maximum (1RM) on subsequent clean performance in female Olympic weightlifters. The results showed that preconditioning with either 85% or 120% 1RM significantly increased clean performance, with the use of 85% 1RM load resulting in less perceived exertion. These findings have important implications for training and competition performance in weightlifters.
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2022)
Article
Sport Sciences
Stephan Geisler, Tim Havers, Eduard Isenmann, Jonas Schulze, Leonie K. Lourens, Jannik Nowak, Steffen Held, Gregory Haff
Summary: This study compared the electromyographic (EMG) activity of different weightlifting exercises and analyzed the influence of weightlifting expertise. The results showed that the EMG activity of the main muscles involved in the exercises was similar at higher intensities, and weightlifting expertise did not affect muscle activity.
JOURNAL OF SPORTS SCIENCE AND MEDICINE
(2023)
Article
Medicine, General & Internal
Aakash Bavishi, Stephanie A. Kliethermes, Bradley Petek, Nathaniel Moulson, Pranav Mellacheruvu, Timothy W. Churchill, Kimberly Harmon, Manesh R. Patel, Aaron L. Baggish, Jonathan A. Drezner, Raja Kannan Mutharasan
Summary: This study aimed to identify risk factors for hospitalization and severe complications in young adults (18-24 years old) diagnosed with COVID-19. The study found that hospitalized patients were more likely to have pre-existing medical conditions and higher BMI compared to healthy college athletes. Moreover, elevated BMI was associated with increased mortality.
Article
Multidisciplinary Sciences
Ana Babic, Michael H. Rosenthal, Tilak K. K. Sundaresan, Natalia Khalaf, Valerie Lee, Lauren K. K. Brais, Maureen Loftus, Leah Caplan, Sarah Denning, Anamol Gurung, Joanna Harrod, Khoschy Schawkat, Chen Yuan, Qiao-Li Wang, Alice A. A. Lee, Leah H. Biller, Matthew B. B. Yurgelun, Kimmie Ng, Jonathan A. A. Nowak, Andrew J. J. Aguirre, Sangeeta N. N. Bhatia, Matthew G. Vander Heiden, Stephen K. van den Eeden, Bette J. J. Caan, Brian M. M. Wolpin
Summary: The study suggests that skeletal muscle loss can be detected on CT imaging 1-2 years before a clinical diagnosis of pancreatic cancer, indicating its potential utility for earlier detection.
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Aric A. Prather, Ethan G. Dutcher, James Robinson, Jue Lin, Elizabeth Blackburn, Frederick M. Hecht, Ashley E. Mason, Elena Fromer, Bresh Merino, Remi Frazier, Julia O'Bryan, Stacy Drury, Elissa S. Epel
Summary: This study compared the impact of different COVID-19 vaccines on the durability of neutralizing antibody responses and identified individual difference factors related to antibody decline. The study found that recipients of BNT162b2 and mRNA-1273 experienced a decline in antibody levels over 6 months, while recipients of Ad26.COV2.S showed a significant increase. At the 6-month time point, antibody levels to Ad26.COV2.S were significantly higher than those to BNT162b2 and equivalent to mRNA-1273. Older age, higher baseline BMI, female gender, and non-smoking status were associated with higher antibody levels.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Mi Kyoung Son, Dae Sub Song, Kyoungho Lee, Hyun-Young Park
Summary: This study aimed to identify modifiable risk factors for atrial fibrillation (AF) in the midlife general population and estimate their impact. The results showed that high systolic blood pressure, obesity with central obesity, and an inactive lifestyle were significantly associated with incident AF. Maintaining or achieving a lower burden of modifiable risk factors was associated with decreased AF risk.
SCIENTIFIC REPORTS
(2022)
Editorial Material
Endocrinology & Metabolism
Ambica Bora, Alexandre Fisette
Summary: Understanding the impact of obesity on the brain and its role in triggering neuroinflammation and neurodegeneration relies on animal models. However, there is a gap between the timeline of human obesity and typical preclinical protocols. This emphasizes the need for chronic obesity models to study the pathophysiology of human obesity.
TRENDS IN ENDOCRINOLOGY AND METABOLISM
(2023)