Common genetic factors for hematological traits in Humans

Genetic Basis of Autoantibody Positive and Negative Rheumatoid Arthritis Risk in a Multi-ethnic Cohort Derived from Electronic Health Records

(2011) Fina Kurreeman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies

(2011) Buhm Han et al.   AMERICAN JOURNAL OF HUMAN GENETICS

HLA-Cw*1202-B*5201-DRB1*1502 Haplotype Increases Risk for Ulcerative Colitis but Reduces Risk for Crohn's Disease

(2011) Yukinori Okada et al.   GASTROENTEROLOGY

PlatinumCNV: A Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data

(2011) Natsuhiko Kumasaka et al.   GENETIC EPIDEMIOLOGY

Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels

(2011) Irene Pichler et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus

(2011) Yukinori Okada et al.   HUMAN MOLECULAR GENETICS

LPAR1 and ITGA4 regulate peripheral blood monocyte counts

(2011) Narelle Maugeri et al.   HUMAN MUTATION

New gene functions in megakaryopoiesis and platelet formation

(2011) Christian Gieger et al.   NATURE

Human metabolic individuality in biomedical and pharmaceutical research

(2011) Karsten Suhre et al.   NATURE

A rare variant in MYH6 is associated with high risk of sick sinus syndrome

(2011) Hilma Holm et al.   NATURE GENETICS

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

(2011) Manuel A Rivas et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

(2011) Norihiro Kato et al.   NATURE GENETICS

A genome-wide association study of metabolic traits in human urine

(2011) Karsten Suhre et al.   NATURE GENETICS

Epigenome-wide association studies for common human diseases

(2011) Vardhman K. Rakyan et al.   NATURE REVIEWS GENETICS

Family-based designs for genome-wide association studies

(2011) Jurg Ott et al.   NATURE REVIEWS GENETICS

Multiple Loci Are Associated with White Blood Cell Phenotypes

(2011) Michael A. Nalls et al.   PLoS Genetics

Identification of Nine Novel Loci Associated with White Blood Cell Subtypes in a Japanese Population

(2011) Yukinori Okada et al.   PLoS Genetics

Genome-Wide Association Study of White Blood Cell Count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT)

(2011) Alexander P. Reiner et al.   PLoS Genetics

Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application

(2010) Rita M. Cantor et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Quantitative Trait Loci for CD4:CD8 Lymphocyte Ratio Are Associated with Risk of Type 1 Diabetes and HIV-1 Immune Control

(2010) Manuel A.R. Ferreira et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study

(2010) W. Tang et al.   BLOOD

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor

(2010) Nicholas L. Smith et al.   CIRCULATION

Apparent polycythaemia: diagnosis, pathogenesis and management

(2010) Maria Messinezy et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Progress and Promise of Genome-Wide Association Studies for Human Complex Trait Genetics

(2010) B. E. Stranger et al.   GENETICS

Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans

(2010) Ken Sin Lo et al.   HUMAN GENETICS

Common variations in PSMD3–CSF3 and PLCB4 are associated with neutrophil count

(2010) Yukinori Okada et al.   HUMAN MOLECULAR GENETICS

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

(2010) Konrad Oexle et al.   HUMAN MOLECULAR GENETICS

A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci

(2010) Yukinori Okada et al.   HUMAN MOLECULAR GENETICS

A revised scheme for developmental pathways of hematopoietic cells: the myeloid-based model

(2010) H. Kawamoto et al.   INTERNATIONAL IMMUNOLOGY

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

(2010)   NATURE

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

(2010) Yuta Kochi et al.   NATURE GENETICS

Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing

(2010) Akihiro Fujimoto et al.   NATURE GENETICS

Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists

(2010) Andrew D Johnson et al.   NATURE GENETICS

Genome-wide association study of hematological and biochemical traits in a Japanese population

(2010) Yoichiro Kamatani et al.   NATURE GENETICS

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

Advances in understanding cancer genomes through second-generation sequencing

(2010) Matthew Meyerson et al.   NATURE REVIEWS GENETICS

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

(2010) Tanja Zeller et al.   PLoS One

A Genome-Wide Association Study of Red Blood Cell Traits Using the Electronic Medical Record

(2010) Iftikhar J. Kullo et al.   PLoS One

Natural selection on EPAS1 (HIF2 ) associated with low hemoglobin concentration in Tibetan highlanders

(2010) C. M. Beall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2008 Japanese Society for Dialysis Therapy: Guidelines for Renal Anemia in Chronic Kidney Disease

(2010) Yoshiharu Tsubakihara et al.   THERAPEUTIC APHERESIS AND DIALYSIS

Sequence Variants in Three Loci Influence Monocyte Counts and Erythrocyte Volume

(2009) Manuel A.R. Ferreira et al.   AMERICAN JOURNAL OF HUMAN GENETICS

HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis

(2009) Y. Okada et al.   ANNALS OF THE RHEUMATIC DISEASES

Contribution of a haplotype in the HLA region to anti–cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA–DRB1

(2009) Yukinori Okada et al.   ARTHRITIS AND RHEUMATISM

A genome-wide association analysis of serum iron concentrations

(2009) T. Tanaka et al.   BLOOD

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

(2009) N. Soranzo et al.   BLOOD

Association of Novel Genetic Loci With Circulating Fibrinogen Levels

(2009) Abbas Dehghan et al.   Circulation-Cardiovascular Genetics

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

(2009) Bruce M. Psaty et al.   Circulation-Cardiovascular Genetics

Novel Loci, Including Those Related to Crohn Disease, Psoriasis, and Inflammation, Identified in a Genome-Wide Association Study of Fibrinogen in 17 686 Women

(2009) Jacqueline S. Danik et al.   Circulation-Cardiovascular Genetics

Haemopoietic processes in allergic disease: eosinophil/basophil development

(2009) G. M. Gauvreau et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Genetic control of resistance to human malaria

(2009) Anthony C Allison   CURRENT OPINION IN IMMUNOLOGY

Basophils: A Nonredundant Contributor to Host Immunity

(2009) Brandon M. Sullivan et al.   IMMUNITY

SNPs in BRAP associated with risk of myocardial infarction in Asian populations

(2009) Kouichi Ozaki et al.   NATURE GENETICS

Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels

(2009) John C Chambers et al.   NATURE GENETICS

Genes determining blood cell traits

(2009) Nancy C Andrews   NATURE GENETICS

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

(2009) Santhi K Ganesh et al.   NATURE GENETICS

Common variants in TMPRSS6 are associated with iron status and erythrocyte volume

(2009) Beben Benyamin et al.   NATURE GENETICS

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

(2009) Daniel F Gudbjartsson et al.   NATURE GENETICS

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

(2009) Nicole Soranzo et al.   NATURE GENETICS

Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide–MHC class II complexes to CD4+ T cells

(2009) Tomohiro Yoshimoto et al.   NATURE IMMUNOLOGY

Detecting gene–gene interactions that underlie human diseases

(2009) Heather J Cordell   NATURE REVIEWS GENETICS

CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2

(2009) T. Okamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced Neutrophil Count in People of African Descent Is Due To a Regulatory Variant in the Duffy Antigen Receptor for Chemokines Gene

(2009) David Reich et al.   PLoS Genetics

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

(2009) Soumya Raychaudhuri et al.   PLoS Genetics

Admixture Mapping of White Cell Count: Genetic Locus Responsible for Lower White Blood Cell Count in the Health ABC and Jackson Heart Studies

(2008) Michael A. Nalls et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Genome-wide Association Study Identifies Three Loci Associated with Mean Platelet Volume

(2008) Christa Meisinger et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Variants in TF and HFE Explain ∼40% of Genetic Variation in Serum-Transferrin Levels

(2008) Beben Benyamin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Shear activates platelet-derived latent TGF- 

(2008) K. Miyazono   BLOOD

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

Alendronate Protects Premenopausal Women from Bone Loss and Fracture Associated with High-dose Glucocorticoid Therapy

(2008) Yosuke Okada et al.   JOURNAL OF RHEUMATOLOGY

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

(2008) Soumya Raychaudhuri et al.   NATURE GENETICS

The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells

(2008) Stephen J Loughran et al.   NATURE IMMUNOLOGY

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of  -thalassemia

(2008) M. Uda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA polymorphisms at the BCL11A, HBS1L-MYB, and  -globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

(2008) G. Lettre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

(2008) X. Du et al.   SCIENCE