Synthesis of phenstatin/isocombretastatin–chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers

Design, synthesis and biological evaluation of imidazopyridine/imidazopyrimidine-benzimidazole conjugates as potential anticancer agents

(2015) Ahmed Kamal et al.   MedChemComm

Microtubule-targeting agents are clinically successful due to both mitotic and interphase impairment of microtubule function

(2014) Jessica J. Field et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design and Synthesis of Aminostilbene-Arylpropenones as Tubulin Polymerization Inhibitors

(2014) Ahmed Kamal et al.   ChemMedChem

Synthesis and anticancer activity evaluation of resveratrol–chalcone conjugates

(2014) Deepak Kumar et al.   MedChemComm

Identification and cost of adverse events in metastatic breast cancer in taxane and capecitabine based regimens

(2014) Ryan N Hansen et al.   SpringerPlus

Synthesis and Biological Evaluation of Imidazopyridine-Oxindole Conjugates as Microtubule-Targeting Agents

(2013) Ahmed Kamal et al.   ChemMedChem

The design and development of imidazothiazole–chalcone derivatives as potential anticancer drugs

(2013) Ahmed Kamal et al.   Expert Opinion on Drug Discovery

A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule

(2012) Zu-long Liu et al.   ACTA PHARMACOLOGICA SINICA

Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors

(2012) Ahmed Kamal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

High-Dose Vincristine Sulfate Liposome Injection for Advanced, Relapsed, and Refractory Adult Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia

(2012) Susan O'Brien et al.   JOURNAL OF CLINICAL ONCOLOGY

Navitoclax (ABT-263) Accelerates Apoptosis during Drug-Induced Mitotic Arrest by Antagonizing Bcl-xL

(2011) J. Shi et al.   CANCER RESEARCH

Synthesis and Antitumor Evaluation of Nitrovinyl Biphenyls: Anticancer Agents Based on Allocolchicines

(2011) Nishant Jain et al.   ChemMedChem

Design and Synthesis of Resveratrol-Based Nitrovinylstilbenes as Antimitotic Agents

(2011) M. Amarnath Reddy et al.   JOURNAL OF MEDICINAL CHEMISTRY

2-Anilinonicotinyl linked 1,3,4-oxadiazole derivatives: Synthesis, antitumour activity and inhibition of tubulin polymerization

(2011) Ahmed Kamal et al.   MedChemComm

Synthesis and Antitumor Activity of 1,5-Disubstituted 1,2,4-Triazoles as Cis-Restricted Combretastatin Analogues

(2010) Romeo Romagnoli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones

(2009) Sylvie Ducki et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia

(2009) R. Crazzolara et al.   BLOOD

Synthesis, Biological Evaluation of 1,1-Diarylethylenes as a Novel Class of Antimitotic Agents

(2009) Abdallah Hamze et al.   ChemMedChem

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

2-Arylamino-4-Amino-5-Aroylthiazoles. “One-Pot” Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization

(2009) Romeo Romagnoli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Isocombretastatins A versus Combretastatins A: The ForgottenisoCA-4 Isomer as a Highly Promising Cytotoxic and Antitubulin Agent

(2009) Samir Messaoudi et al.   JOURNAL OF MEDICINAL CHEMISTRY

S9, a Novel Anticancer Agent, Exerts Its Anti-Proliferative Activity by Interfering with Both PI3K-Akt-mTOR Signaling and Microtubule Cytoskeleton

(2009) Chao Zhang et al.   PLoS One

Cell Cycle-Related Cyclin B1 Quantification

(2009) Phyllis S. Frisa et al.   PLoS One

Expeditious synthesis of 1,1-diarylethylenes related to isocombretastatin A-4 (isoCA-4) via palladium-catalyzed arylation of N-tosylhydrazones with aryl triflates

(2009) Bret Tréguier et al.   TETRAHEDRON LETTERS

Synthesis and antitumor activity of benzils related to combretastatin A-4

(2008) Céline Mousset et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Microtubule assembly dynamics: An attractive target for anticancer drugs

(2008) Parminder Singh et al.   IUBMB LIFE

Microtubules: A dynamic target in cancer therapy

(2008) Eddy Pasquier et al.   IUBMB LIFE

One-pot hydrosilylation–protodesilylation of functionalized diarylalkynes: a highly selective access to Z-stilbenes. Application to the synthesis of combretastatin A-4

(2007) Anne Giraud et al.   TETRAHEDRON LETTERS