Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family

An Integrated Computational and Experimental Approach to Gaining Selectivity for MMP-2 within the Gelatinase Subfamily

(2014) Benjamin Fabre et al.   CHEMBIOCHEM

New clicked thiirane derivatives as gelatinase inhibitors: the relevance of the P1′ segment

(2014) B. Fabre et al.   RSC Advances

Progress towards water-soluble triazole-based selective MMP-2 inhibitors

(2013) Benjamin Fabre et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Inhibiting Matrix Metalloproteinases, an Old Story with New Potentials for Cancer Treatment

(2012) Dimitris Stellas et al.   Anti-Cancer Agents in Medicinal Chemistry

MMP-2 Selectivity in Hydroxamate-Type Inhibitors

(2012) P. Serra et al.   CURRENT MEDICINAL CHEMISTRY

Inflammatory Mechanisms in Atherosclerosis: The Impact of Matrix Metalloproteinases

(2012) Gerasimos Siasos et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

MM-ISMSA: An Ultrafast and Accurate Scoring Function for Protein–Protein Docking

(2012) Javier Klett et al.   Journal of Chemical Theory and Computation

Continuous flow photolysis of aryl azides: Preparation of 3H-azepinones

(2011) Farhan R Bou-Hamdan et al.   Beilstein Journal of Organic Chemistry

Efficient Incorporation of Protein Flexibility and Dynamics into Molecular Docking Simulations

(2011) Markus A. Lill   BIOCHEMISTRY

New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression

(2011) Brigitte Bauvois   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Recent Advances in Studies on Hydroxamates as Matrix Metalloproteinase Inhibitors: A Review

(2011) R.K. Yadav et al.   CURRENT MEDICINAL CHEMISTRY

Matrix metalloproteinases in acute lung injury: mediators of injury and drivers of repair

(2011) A. Davey et al.   EUROPEAN RESPIRATORY JOURNAL

Matrix Metalloproteinases and Descending Aortic Aneurysms: Parity, Disparity, and Switch

(2011) Tom P. Theruvath et al.   JOURNAL OF CARDIAC SURGERY

The advent and evolution of QSAR at Pomona College

(2011) Corwin Hansch   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Potent “Clicked” MMP2 Inhibitors: Synthesis, Molecular Modeling and Biological Exploration

(2011) Jose María Zapico et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Physiology and pathophysiology of matrix metalloproteases

(2010) T. Klein et al.   AMINO ACIDS

Orally bioavailable dual MMP-1/MMP-14 sparing, MMP-13 selective α-sulfone hydroxamates

(2010) Stephen A. Kolodziej et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Temporal and Spatial Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Following Myocardial Infarction

(2010) Merry L. Lindsey et al.   Cardiovascular Therapeutics

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease

(2010) Daniel P. Becker et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?

(2010) S. Rivera et al.   JOURNAL OF NEUROSCIENCE

Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer

(2009) Roopali Roy et al.   JOURNAL OF CLINICAL ONCOLOGY