Inhibitory effects of Rap1GAP overexpression on proliferation and migration of endothelial cells via ERK and Akt pathways

Downregulation of Rap1GAP through Epigenetic Silencing and Loss of Heterozygosity Promotes Invasion and Progression of Thyroid Tumors

(2010) H. Zuo et al.   CANCER RESEARCH

Downregulation of Rap1GAP in Human Tumor Cells Alters Cell/Matrix and Cell/Cell Adhesion

(2010) O. M. Tsygankova et al.   MOLECULAR AND CELLULAR BIOLOGY

A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis

(2009) R. C. Doebele et al.   BLOOD

Down-regulation of Rap1GAP via Promoter Hypermethylation Promotes Melanoma Cell Proliferation, Survival, and Migration

(2009) H. Zheng et al.   CANCER RESEARCH

Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis

(2008) G. Carmona et al.   BLOOD

Rap1GAP Promotes Invasion via Induction of Matrix Metalloproteinase 9 Secretion, Which Is Associated with Poor Survival in Low N-Stage Squamous Cell Carcinoma

(2008) R. S. Mitra et al.   CANCER RESEARCH

The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages

(2008) Uma K. Misra et al.   CELLULAR SIGNALLING

Loss of Rap1GAP in Papillary Thyroid Cancer

(2008) Anoma Nellore et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Rap1a Is a Key Regulator of Fibroblast Growth Factor 2-Induced Angiogenesis and Together with Rap1b Controls Human Endothelial Cell Functions

(2008) J. Yan et al.   MOLECULAR AND CELLULAR BIOLOGY