Article
Clinical Neurology
Ji Hyun An, Hong Jin Jeon, Seong-Jin Cho, Sung Man Chang, Byung-Soo Kim, Bong-Jin Hahm, Jong-Ik Park, Jin Pyo Hong
Summary: Subthreshold levels of depression and anxiety are prevalent among Koreans and are associated with an increased prevalence of lifetime suicide attempts.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Kaito Kageyama, Yudai Kato, Takanori Mesaki, Hiroyuki Uchida, Kana Takahashi, Risako Marume, Yoshiyuki Sejima, Kazuki Hirao
Summary: A pilot RCT was conducted to assess the efficacy of SPSRS application intervention for people with subthreshold depression. The results showed that the experimental group displayed medium, small, and small improvements in depressive symptoms compared to the control group after the 5-week intervention.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Health Care Sciences & Services
Aline Schonenberg, Hannah M. Zipprich, Ulrike Teschner, Julian Grosskreutz, Otto W. Witte, Tino Prell
Summary: Depression has a significant impact on quality of life in Parkinson's disease patients, especially those with normal cognitive function. More attention should be focused on treating depression and subthreshold depression in medical care.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2021)
Article
Clinical Neurology
Ruwei Ou, Qianqian Wei, Yanbing Hou, Lingyu Zhang, Kuncheng Liu, Xiangwei Kong, Shuying Li, Lan Wang, Xianran Xu, Xiaojing Gu, Junyu Lin, Zheng Jiang, Jiao Liu, Wei Song, Bei Cao, Huifang Shang
Summary: Patients with early-onset Parkinson's disease (EOPD) have a higher prevalence of suicidal ideation (SI) and depression, with risk factors including depression, non-smoking, and lower education level.
JOURNAL OF NEUROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Alvaro I. Langer, Marcelo A. Crockett, Mariori Bravo-Contreras, Carolina Carrillo-Naipayan, Matias Chaura-Mario, Barbara Gomez-Curumilla, Claudia Henriquez-Pacheco, Rodrigo C. Vergara, Jorge Santander, Zayra Antunez, Tomas Baader
Summary: This study aimed to investigate the prevalence of subthreshold depressive episodes and major depressive episodes in college students during the COVID-19 pandemic in southern Chile, as well as the association between social and economic factors and these depressive symptoms. The results showed that both subthreshold and major depressive symptoms were common in college students, and their associations with social and economic factors varied.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Neurosciences
Xue-ning Li, Da-peng Hao, Mei-jie Qu, Meng Zhang, An-bang Ma, Xu-dong Pan, Ai-jun Ma
Summary: By combining plasma FAM19A5 and MRI-based radiomics, the study successfully developed a predictive tool for PD and PDD, which showed excellent accuracy in clinical settings.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Clinical Neurology
Wonjeong Jeong, Hyunkyu Kim, Jae Hong Joo, Sung-In Jang, Eun-Cheol Park
Summary: The study found that individuals with depression are at a higher risk of developing Parkinson's disease, especially among those with disabilities. Additionally, individuals with depression have a higher risk of PD based on the Charlson Comorbidity Index (CCI) score compared to their counterparts.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Geriatrics & Gerontology
Gregory M. Pontone, Kelly A. Mills
Summary: Depression and anxiety are common and significantly impact quality of life in Parkinson's disease. Current management strategies need to address both motor and psychiatric symptoms, but there is a lack of randomized controlled trials for pharmacological treatment of anxiety and nonpharmacological interventions have not shown efficacy.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2021)
Article
Behavioral Sciences
Samuel Weiss-Cowie, Paul Verhaeghen, Audrey Duarte
Summary: This meta-analysis examines the relationship between Overgeneral Autobiographical Memory (OGM) and depression. The results show that depressed individuals have decreased autobiographical memory specificity and increased categoricity compared to controls. The severity of OGM is more pronounced in clinically diagnosed major depressive disorder (MDD) than in subthreshold and remitted depression, although deficits are still present in the latter groups. The study emphasizes the need for a broader range of testing paradigms and consideration of non-clinical depression in future research.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Psychiatry
Miaomiao Hou, Xiaowei Mao, Xiaojun Hou, Kunpeng Li
Summary: Our study found a mild-to-moderate level of stigma in patients with PD. Tremor-dominant subtype, longer disease duration, younger age, severe motor symptoms, and depression are predictors of stigma in PD.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Multidisciplinary Sciences
Ria Shah, Joy Read, Nathan Davies, Danielle Nimmons, Jennifer Pigott, Anette Schrag, Kate Walters, Megan Armstrong
Summary: This study aimed to explore how people living with Parkinson's self-manage their condition and identify areas needed to be incorporated into self-management resources or interventions. The study identified three main themes: management of physical symptoms, management of emotional impact, and barriers to self-management.
Article
Geriatrics & Gerontology
Nicole Mercado Fischer, Jared T. Hinkle, Kate Perepezko, Catherine C. Bakker, Meaghan Morris, Martinus P. G. Broen, Ankur Butala, Ted M. Dawson, Albert F. G. Leentjens, Zoltan Mari, Cherie L. Marvel, Kelly A. Mills, Liana S. Rosenthal, Melissa D. Shepard, Alexander Pantelyat, Arnold Bakker, Olga Pletnikova, Juan C. Troncoso, Jiangxia Wang, Gregory M. Pontone
Summary: The study found that some Parkinson's disease patients had psychosis and depression, which were closely related to neuronal loss and gliosis in the substantia nigra but not in the locus coeruleus. Psychosis and depression were associated with the severity of neuronal loss and gliosis in the substantia nigra, while anxiety did not show such association.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2021)
Article
Clinical Neurology
Blake K. Noyes, Douglas P. Munoz, Sarosh Khalid-Khan, Elisa Brietzke, Linda Booij
Summary: Subthreshold depression and major depressive disorder in adolescents share similarities in several aspects, including higher prevalence, functional impairment, comorbidity, genetic predisposition, and treatment response. However, the definition of subthreshold depression varies across studies, and adolescent-specific data are limited.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Lina Huang, Guofeng Huang, Qingguo Ding, Pei Liang, Chunhong Hu, Hongqiang Zhang, Linlin Zhan, Qianqian Wang, Yikang Cao, Jun Zhang, Wenbin Shen, Xize Jia, Wei Xing
Summary: Through an eight-week aerobic exercise intervention in Subthreshold depression (StD) individuals, this study found changes in spontaneous brain activity post-exercise, providing further support for the hypothesis that physical exercise can help reshape the brain activity patterns of StD patients.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
D. Santos-Garcia, T. de Deus Fonticoba, C. Cores Bartolome, E. Suarez Castro, S. Jesus, P. Mir, B. Pascual-Sedano, J. Pagonabarraga, J. Kulisevsky, J. Hernandez-Vara, L. L. Planellas, I. Cabo-Lopez, M. Seijo-Martinez, I. Legarda, F. Carrillo Padilla, N. Caballol, E. Cubo, V. Nogueira, M. G. Alonso Losada, N. Lopez Ariztegui, I. Gonzalez Aramburu, J. Garcia Caldentey, C. Borrue, C. Valero, P. Sanchez Alonso
Summary: The study found that Parkinson's disease patients with impulsive-compulsive behaviors are more likely to suffer from depression, particularly in relation to pathological gambling, compulsive eating behavior, and hobbyism-punding.
JOURNAL OF AFFECTIVE DISORDERS
(2021)