Article
Ophthalmology
Mahmoud Abdel-Radi, Hazem Abdelmotaal, Mohamed Anwar
Summary: The use of femtosecond laser technology in performing thin-flap LASIK eye surgeries has improved the outcome of post-LASIK dry eye when compared with the mechanical microkeratome. Dry eye parameters deteriorated at 3 months after surgery but showed improvement at 6 months, though not returning to baseline.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2022)
Article
Multidisciplinary Sciences
Yu-Chi Liu, Gary Hin-Fai Yam, Molly Tzu-Yu Lin, Ericia Teo, Siew-Kwan Koh, Lu Deng, Lei Zhou, Louis Tong, Jodhbir S. Mehta
Summary: This study investigated and compared tear proteomic and neuromediator profiles following SMILE and LASIK procedures, revealing significant differences at different time points between the two procedures, despite ultimately converging clinical dry eye signs.
JOURNAL OF ADVANCED RESEARCH
(2021)
Article
Ophthalmology
Oriel Spierer, Achia Nemet, Stav Bloch, Asaf Israeli, Michael Mimouni, Igor Kaiserman
Summary: This study aimed to evaluate the impact of asymptomatic meibomian gland dysfunction (MGD) on laser-assisted in situ keratomileusis (LASIK) outcomes. The results showed that patients with preoperative asymptomatic MGD had similar LASIK outcomes compared to those without MGD, indicating that no specific preoperative MGD treatment or caution is necessary in such cases.
OPHTHALMOLOGY AND THERAPY
(2023)
Article
Ophthalmology
Youming Zhou, Yunxuan Ou, Man Pan Chin, Dongfeng Zhao, Riping Zhang
Summary: The aim of this study was to compare the difference in binocular visual function for high and low-moderate myopes before and after FS-LASIK. The results showed a transient change in binocular visual function after 7 days of the surgery, which returned to the baseline level after 30 days.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Cell Biology
Hung-Chi Chen, Shun-Fa Yang, Chia-Yi Lee, Yi-Jen Hsueh, Jing-Yang Huang, Chao-Kai Chang
Summary: This study compared the effects of femtosecond laser in situ keratomileusis (FS-LASIK) and laser-assisted lenticule extraction (LALEX) on total antioxidant capacity (TAC) and ascorbic acid (AA). The results showed that LALEX surgery caused a smaller reduction in ascorbic acid, especially in patients with dry eye disease.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2023)
Article
Health Care Sciences & Services
Jae-Yong Kim, Hun Lee, Choun-Ki Joo, Joon-Young Hyon, Tae-Im Kim, Jin-Hyoung Kim, Jin-Kuk Kim, Eun-Young Cho, Ji-Eun Choi, Na-Rae Lee, Hung-Won Tchah
Summary: In a Korean population, myopic LASIK was shown to be effective and safe with high refractive predictability, although myopic regression may occur over time. Higher preoperative SE and lower preoperative BCVA are predictive of a low postoperative efficacy.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Medicine, General & Internal
Majid Moshirfar, Noor F. Basharat, Nour Bundogji, Emilie L. Ungricht, Ines M. Darquea, Matthew E. Conley, Yasmyne C. Ronquillo, Phillip C. Hoopes
Summary: This study evaluated the safety, efficacy, and predictability of laser-assisted in situ keratomileusis (LASIK) enhancement after primary LASIK and compared the outcomes to FDA criteria. The results showed that LASIK enhancements produced favorable visual outcomes and met FDA benchmarks for safety, efficacy, and predictability. Older age, female sex, right eye, and larger sphere, cylinder, and spherical equivalent were identified as risk factors for enhancement. Additionally, the risk of epithelial ingrowth significantly increased when the duration between primary and enhancement procedures exceeded five years.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Engineering, Electrical & Electronic
Zhoulyu Rao, Yuntao Lu, Zhengwei Lie, Kyoseung Sim, Zhenqiang Ma, Jianliang Xiao, Cunjiang Yu
Summary: The study focuses on creating shape-adaptive imagers using kirigami design in ultrathin silicon pixels, with high pixel fill factors. These imagers can adjust shape for imaging applications requiring low optical aberration and tunable focusing power. Additionally, combining a concave-shaped imager with a tunable lens allows for adaptive optical focus to capture distant and near objects with low aberration.
NATURE ELECTRONICS
(2021)
Article
Engineering, Biomedical
Mingna Liu, Weiyun Shi, Xin Liu, Na Li, Tong Chen, Hua Gao
Summary: This study compared the postoperative corneal biomechanics in high myopia patients undergoing FS-LASIK and LASEK, finding that LASEK had a smaller impact on corneal biomechanics and may pose a lower risk of postoperative corneal ectasia compared to FS-LASIK.
LASERS IN MEDICAL SCIENCE
(2021)
Article
Biotechnology & Applied Microbiology
Chenyan Wang, Xiaona Li, Yuan Guo, Rui He, Hongmei Guo, Weiyi Chen
Summary: This study analyzed the impact of LASIK and SMILE surgeries on the biomechanical behaviors of the cornea through a three-dimensional finite element model. The results suggest that compared to LASIK surgery, SMILE may have a lower risk of corneal ectasia, and creating a corneal cap instead of a corneal flap may help improve corneal biomechanical stability.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Medicine, General & Internal
Yang Jiang, Zhonghai Wang, Ying Li, Yong Li, Thomas Chengxuan Lu
Summary: The study found that there were alterations in retinal foveal and RNFL measurements by OCT 1 hour and 1 day after FS-LASIK surgery.
FRONTIERS IN MEDICINE
(2021)
Article
Engineering, Biomedical
Ge Tian, Tong Chen, Xin Liu, Yue Lin, Na Li, Hua Gao, Mingna Liu
Summary: This study compared the central corneal thickness (CCT) treated with different surgical methods for myopia correction and found no significant difference in the measured CCT reduction postoperatively among small incision lenticule extraction (SMILE), femtosecond laser-assisted in situ keratomileusis (FS-LASIK), and laser-assisted subepithelial keratomileusis (LASEK). However, the predicted CCT reduction was significantly different, with SMILE being overestimated and FS-LASIK and LASEK being underestimated. This suggests that the laser platform may have some biases in predicting the CCT reduction.
LASERS IN MEDICAL SCIENCE
(2023)
Article
Ophthalmology
Gorka Lauzirika, Montserrat Garcia-Gonzalez, Gema Bolivar, Jose Luis Hernandez-Verdejo, Vanesa Blazquez Sanchez, Juan Gros-Otero, Miguel A. Teus
Summary: This study measured the intraocular pressure (IOP) elevation during LASIK flap creation using the WaveLight FS200 femtosecond (FS) laser platform in an ex vivo animal model. The results showed a low to moderate increase in IOP during the procedure, with a total surgical time of approximately 29.5 seconds. The use of the WaveLight FS200 was considered safe due to the relatively mild IOP elevation during LASIK flap creation.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Urusha Maharjan, Sujata Rijal, Ashutosh Jnawali, Sanjeeta Sitaula, Sanjeev Bhattarai, Gulshan Bahadur Shrestha
Summary: The purpose of this study was to investigate the binocular vision status in normally-sighted school aged children who used digital devices. The results showed that children who used digital devices for a longer period of time had significantly reduced amplitudes of accommodation, accommodative facility, and positive fusional vergence.
Review
Medicine, General & Internal
Piotr Kanclerz, Ramin Khoramnia
Summary: The study compared flap thickness and complications related to flap creation using femtosecond lasers and mechanical microkeratomes in LASIK surgery. The results showed that femtosecond lasers had slightly better performance in terms of flap thickness and lower likelihood of specific complications compared to mechanical microkeratomes. Overall, both techniques had low rates of intra- and postoperative complications.
Article
Engineering, Aerospace
Jingqi Li, Yaosong Long, Mao Su, Lei Liu, Bo Wang, Zhongtao Cheng
Summary: In this paper, a fault-tolerant guidance method based on the MPC framework is proposed for the vertical landing of reusable rockets. The method combines a trajectory optimization algorithm with the MPC framework to form a robust closed loop. An integrated GNC system is also designed to enhance fault tolerance and robustness. Simulation experiments show that the method is fault-tolerant and has the potential for online use.
INTERNATIONAL JOURNAL OF AEROSPACE ENGINEERING
(2022)
Review
Cardiac & Cardiovascular Systems
Qianru Leng, Jie Ding, Meiyan Dai, Lei Liu, Qing Fang, Dao Wen Wang, Lujin Wu, Yan Wang
Summary: This paper elaborates on the roles of platelet-derived miRNAs in cardiovascular disease and cancer, emphasizing the importance of these molecules for human health and their critical roles in the occurrence and development of diseases.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Engineering, Aerospace
Binghe An, Bo Wang, Huijin Fan, Lei Liu, Hui Hu, Yongji Wang
Summary: This paper presents a novel fully distributed prescribed performance formation controller for multiple quadrotor unmanned aerial vehicles. The controller introduces a performance function and utilizes a distributed adaptive extended state observer to estimate the leader's maneuver and external disturbances, ensuring the desired formation pattern and prescribed performance requirements.
AEROSPACE SCIENCE AND TECHNOLOGY
(2022)
Article
Hematology
Lijun Zhao, Shuhong Li, Xiaoyi Wei, Xuexiu Qi, Dong Liu, Lei Liu, Feiqiu Wen, Ji-shuai Zhang, Feng Wang, Ze-lin Liu, Yu J. Cao
Summary: This study developed a novel approach for enhancing antitumor efficacy and overcoming immune escape by designing a CD19/CD22/CD3 trispecific antibody (tsAb). The optimized tsAb showed superior ability in inducing T-cell-specific cytotoxicity and cytokine production against CD19+ and/or CD22+ tumor cells compared to other tsAb formats. It also demonstrated significantly enhanced anti-tumor efficacy and the ability to overcome immune escape.
Article
Materials Science, Ceramics
Lei Liu, Zijian Zhou, Xiangkun Elvis Cao, Yue Zhou, Dejun Peng, Ying Liu, Xiaowei Liu, Minghou Xu
Summary: Many dopants have been explored to improve the heat storage performance and sintering resistance of Co3O4, but the performance of these materials is not comparable due to different synthesis methods and test conditions. This study systematically compared and screened nine dopants, including four unreported ones, under the same conditions. The results showed that Cu and Zr doping had the highest re-oxidation rate, while Si and Mg doping had adverse effects on the conversion rate. Cu-doped sample exhibited higher re-oxidation rate and energy density, while Zr-doped sample exhibited more stable cyclability.
CERAMICS INTERNATIONAL
(2023)
Article
Medical Laboratory Technology
Yuying Chen, Jian Liu, Yu Su, Huiru Zhao, Yujing Zhao, Meng Wen, Shan Lu, Xiangyu Cao, Wenjie Zhang, Lei Liu, Jun Wu
Summary: This study found that the levels of AV-TF+ MPs significantly increased on postoperative day 5 in patients with VTE, indicating the development of VTE and serving as predictive markers in joint arthroplasty patients.
CLINICA CHIMICA ACTA
(2022)
Article
Automation & Control Systems
Lei Liu, Yongxiong Liu, Lilin Zhou, Bo Wang, Zhongtao Cheng, Huijin Fan
Summary: In this paper, the application of active disturbance rejection control (ADRC) based on a neural network for the attitude control of a hypersonic vehicle (HV) with uncertain disturbances is investigated. The strong coupling of the HV poses challenges for separate ADRC design for each channel. A cascade active-rejection control scheme is proposed to mitigate this issue, using a Radial Basis Function (RBF) Neural Network instead of the Extended State Observer (ESO) in ADRC. The proposed NNESO-based cascade ADRC demonstrates effective disturbance resistance for HV control.
JOURNAL OF THE FRANKLIN INSTITUTE-ENGINEERING AND APPLIED MATHEMATICS
(2023)
Article
Automation & Control Systems
Xiao Han, Lei Liu, Huijin Fan, Zhongtao Cheng
Summary: This paper investigates the robust approximate optimal control problem for air-breathing hypersonic vehicle (AHV) and proposed a robust approximate optimal controller based on adaptive dynamic programming (ADP). By input-output linearization and introducing auxiliary variables, the high-order nonlinear AHV dynamics are transformed to a second-order feedback decoupling model. The proposed controller considers both robustness and input cost, optimizes control actions, and avoids chattering. The use of a single critic network design ensures system stability and simplifies implementation. Simulation results demonstrate the effectiveness of the proposed scheme.
INTERNATIONAL JOURNAL OF ROBUST AND NONLINEAR CONTROL
(2023)
Article
Automation & Control Systems
Hui Hu, Bo Wang, Lei Liu, Zhongtao Cheng
Summary: In this paper, a new adaptive time-varying barrier Lyapunov function (A-TBLF) is proposed for spacecrafts with adaptive time-varying state constraints. The A-TBLF method adapts the barrier in real-time to ensure convergence of the constrained state into a predefined domain. It also includes a barrier update restart scheme to prevent barrier violations. Additionally, a nonlinear margin function is introduced to avoid input saturation and a finite-time estimation adaptive observer chain is proposed for accurate control input design.
INTERNATIONAL JOURNAL OF ROBUST AND NONLINEAR CONTROL
(2023)
Article
Automation & Control Systems
Xinpeng Fang, Huijin Fan, Wei Wang, Lei Liu, Bo Wang, Zhongtao Cheng
Summary: In this article, an adaptive finite-time fault-tolerant control (FTC) strategy is proposed for state tracking of uncertain systems subject to actuator faults and input saturation. The proposed control scheme effectively deals with the coupling of unknown model uncertainties and actuator faults using an adaptive mechanism based on a wisely chosen Lyapunov function. Simulation and comparison results in a flight control system show the effectiveness and advantages of the proposed control scheme.
IEEE TRANSACTIONS ON SYSTEMS MAN CYBERNETICS-SYSTEMS
(2023)
Article
Automation & Control Systems
Huijin Fan, Xinpeng Fang, Wei Wang, Jiangshuai Huang, Lei Liu
Summary: This paper studies the fault-tolerant control problem for a class of nonlinear systems with uncertain parameters and unknown actuator failures. An adaptive fault-tolerant control scheme based on event-triggered strategy is proposed, and a set of event-triggering conditions are designed for both the controller and the parameter estimators. It has been proven that the closed-loop signals are globally uniformly bounded and the system output converges to a compact set. A modified fault-tolerant control scheme is also designed for the case with a finite number of failures, ensuring the asymptotic convergence of system states. The effectiveness of the proposed schemes is illustrated through a robot manipulator example.
Article
Automation & Control Systems
Wenzhe Fu, Lei Liu, Bo Wang, Zhongtao Cheng, Yongji Wang
Summary: This paper proposes a model predictive static programming (MPSP) based solution to the challenging problem of ascent energy management for hypersonic vehicles using solid rocket boosters. A Bezier spline guidance method is introduced to generate high-quality reference trajectories and improve the performance of MPSP. An online parameter estimation based on the extended Kalman filter is employed to address parametric uncertainties. Numerical simulations demonstrate the effectiveness and robustness of the proposed algorithm in guiding hypersonic vehicles to a given terminal state under uncertainties and outperforming existing methods.
INTERNATIONAL JOURNAL OF ADAPTIVE CONTROL AND SIGNAL PROCESSING
(2023)
Article
Engineering, Aerospace
Gaoxiang Peng, Bo Wang, Lei Liu, Huijin Fan, Zhongtao Cheng
Summary: In this article, a real-time entry trajectory generation algorithm with modular policy is proposed to achieve adaptability to various missions. Deep reinforcement learning is utilized to train two modules, providing a reliable trajectory and solving state misalignment and contradiction.
AEROSPACE SCIENCE AND TECHNOLOGY
(2023)
Article
Automation & Control Systems
Xinpeng Fang, Huijin Fan, Lei Liu, Bo Wang
Summary: The paper focuses on a class of interconnected nonlinear systems with unknown sensor faults and uncertain interactions. A decentralized adaptive fault-tolerant control (FTC) scheme is proposed to compensate for the effects of faults in the control loop. The effectiveness of the proposed scheme is demonstrated through simulation and comparison studies.
JOURNAL OF CONTROL AND DECISION
(2023)
Article
Engineering, Aerospace
Z. Y. Yin, B. Wang, R. T. Xiong, Z. Xiang, L. Liu, H. J. Fan, C. L. Xue
Summary: This paper investigates the constrained attitude control problem of hypersonic vehicles and proposes an improved prescribed performance dynamic surface control method. An adaptive scaling strategy is introduced to avoid state violation, and a nonlinear disturbance observer is used to compensate system disturbances. Numerical simulations demonstrate the effectiveness and superiority of the proposed method.
AERONAUTICAL JOURNAL
(2023)
