Article
Psychiatry
Matteo Panero, Enrica Marzola, Tiziano Tamarin, Annalisa Brustolin, Giovanni Abbate-Daga
Summary: Patients with both anorexia nervosa and major depressive disorder did not show significant differences in psychopathology upon admission, but a full diagnosis of major depressive disorder, rather than just the presence of depressive symptoms, was associated with longer hospital stays and poorer clinical outcomes, such as weight restoration and increased caloric intake. Healthcare policies should take into account that comorbid major depressive disorder, regardless of severity of anorexia nervosa, can impact the effectiveness and timing of acute treatments.
PSYCHIATRY RESEARCH
(2021)
Article
Medicine, General & Internal
Claudia Gulea, Rosita Zakeri, Jennifer K. Quint
Summary: Through latent class analysis, this study identified five clusters of comorbidities in HF patients and found that patients in the metabolic-vascular group had the worst prognosis, while the anemic group had intermediate risk. There were also variations in healthcare use among different comorbidity groups.
Article
Geriatrics & Gerontology
Melissa Y. Wei
Summary: This study examined the association between multimorbidity measured by a physical functioning weighted International Classification of Diseases (ICD)-coded multimorbidity-weighted index (MWI-ICD) and readmissions and mortality. The results showed that multimorbidity using MWI-ICD was significantly associated with an increased risk of readmissions, mortality, and longer length of stay.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Review
Endocrinology & Metabolism
Vandana Raman, Anshu Gupta, Ambika P. Ashraf, Emily Breidbart, Evgenia Gourgari, Manmohan Kamboj, Brenda Kohn, Sowmya Krishnan, Amit Lahoti, Kristal Matlock, Shilpa Mehta, Sejal Mistry, Ryan Miller, Laura Page, Danielle Reynolds, Joan C. Han
Summary: This review focuses on recent advances in pharmacotherapy for pediatric obesity, including medications for rare monogenic forms of obesity. In addition to approved medications for weight reduction in children, off-label medications also have a broad safety margin. The review aims to provide guidance for clinicians and encourage further research into pharmacotherapy and other interventions for pediatric obesity.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Computer Science, Information Systems
Dulce E. Alarcon-Yaquetto, Jean P. Tincopa, Daniel Guillen-Pinto, Nataly Bailon, Cesar P. Carcamo
Summary: The study found that reading augmented reality (AR) books can reduce salivary cortisol levels to a certain extent in hospitalized pediatric patients, but the decrease is not significant. Compared to reading a standard children's book, AR books can improve the VAS score for psychological stress.
INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
(2021)
Article
Endocrinology & Metabolism
Martina Recalde, Andrea Pistillo, Sergio Fernandez-Bertolin, Elena Roel, Maria Aragon, Heinz Freisling, Daniel Prieto-Alhambra, Edward Burn, Talita Duarte-Salles
Summary: The study revealed a positive association between BMI and the risks of COVID-19 diagnosis and hospitalization, while a J-shaped relationship with mortality was observed, particularly among younger patients. Further research is needed to understand the mechanisms underlying these relationships.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Respiratory System
Conrad Krawiec, Xinying Fang, Shouhao Zhou, Duane Williams, Neal J. Thomas
Summary: This study examined the persistence of obesity in pediatric patients diagnosed with status asthmaticus, finding that overweight/obese children with status asthmaticus were significantly more likely to remain obese 5 years after diagnosis compared to those who were underweight/healthy weight at baseline. It highlights the importance of evaluating nutrition, physical activity, and asthma control in obese asthmatic children to reduce the risk of persistent obesity and future asthma exacerbations.
CLINICAL RESPIRATORY JOURNAL
(2021)
Article
Pharmacology & Pharmacy
Arantza Sanvisens, Anna Hernandez-Rubio, Paola Zuluaga, Daniel Fuster, Esther Papaseit, Sara Galan, Magi Farre, Robert Muga
Summary: This study examined the relationship between baseline medical comorbidity and long-term medical outcomes in CUD patients, revealing that baseline comorbidity predicts hospitalization and mortality, with patients having a VACS Index >40 being 3.5 times more likely to die compared to those with VACS <20.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Psychology, Multidisciplinary
Marie-Noelle Klein, Ursina Jufer-Riedi, Sarah Rieder, Celine Hochstrasser, Michelle Steiner, Li Mei Cao, Anthony Feinstein, Sandra Bigi, Karen Lidzba
Summary: Information processing speed (IPS) is a marker for cognitive function that varies with age. The computerized symbol digit modalities test (c-SDMT) is an alternative method that does not require fine motor skills and is suitable for both inpatient and outpatient populations.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Infectious Diseases
Boyan K. Tsankov, Joannie M. Allaire, Michael A. Irvine, Alison A. Lopez, Laura J. Sauve, Bruce A. Vallance, Kevan Jacobson
Summary: Children with comorbidities are at higher risk of severe COVID-19 infection and associated mortality, with a significantly increased risk compared to healthy children. Obese children also have a higher risk of COVID-19 infection.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Nutrition & Dietetics
Nasser M. Al-Daghri, Osama E. Amer, AbdulAziz Hameidi, Hanan Alfawaz, Mohammed Alharbi, Malak N. K. Khattak, Abdullah M. Alnaami, Naji J. Aljohani, Ghadah Alkhaldi, Kaiser Wani, Shaun Sabico
Summary: This 12-month study examined the effects of hybrid educational lifestyle modifications on glycemic control among Saudi youth. The results showed that this intervention program modestly reduced the risk of type 2 diabetes among youth with elevated HbA1c levels.
Article
Cardiac & Cardiovascular Systems
Marco Canepa, Lucia Leporatti, Luca Persico, Pietro Ameri, Italo Porto, Filippo Ansaldi, Marcello Montefiori
Summary: This study used a large administrative database from Liguria to investigate hospital readmissions in elderly patients with heart failure. It found that a quarter of patients contributed to more than half of the readmissions, with a negative impact on prognosis. The study also identified male gender, lower educational level, and higher comorbidity index as predictors of increased readmissions and mortality.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Review
Medicine, Research & Experimental
Dao-Han Zhang, Ying-Hui Fan, Yu-Qiu Zhang, Hong Cao
Summary: Pain and obesity, as well as their associated impairments, are major health concerns. Understanding the relationship between the two is the focus of a growing body of research. This review analyzes neuroendocrine and neuroimmune modulators involved in both pain and obesity, providing insights into nociceptive and anti-nociceptive mechanisms and discussing immune activities and metabolic alterations in their interactions with the neuroendocrine system.
Article
Health Care Sciences & Services
David Monterde, Gerard Carot-Sans, Miguel Cainzos-Achirica, Sonia Abilleira, Marc Coca, Emili Vela, Montse Cleries, Damia Valero-Bover, Josep Comin-Colet, Luis Garcia-Eroles, Pol Perez-Sust, Miquel Arrufat, Yolanda Lejardi Estevez, Jordi Piera-Jimenez
Summary: The comprehensive Queralt DxS comorbidity index showed better performance in predicting critical illness in hospitalized COVID-19 patients compared to other commonly used measures, indicating that the ability of comorbidity indices to predict critical illness increased with their exhaustivity.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2021)
Article
Pediatrics
Frederico Friedrich, Laura de Castro e Garcia, Lucas Montiel Petry, Marina Puerari Pieta, Gustavo Eggers Carvalho, Giovani Zocche, Renata Ongaratto, Magali Santos Lumertz, Marcos Brum, Renato T. Stein, Marcelo C. Scotta, Marcus Herbert Jones, Leonardo Araujo Pinto
Summary: During the COVID-19 pandemic in Brazil, there was a significant decrease in pneumonia hospitalizations for children aged 0-14, especially in those under 9 years old. This reduction may be attributed to the nonpharmacological measures implemented to control the spread of SARS-CoV-2.
PEDIATRIC PULMONOLOGY
(2021)