Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 13, Issue 6, Pages 1763-1767Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob02413c
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Spectroscopic and in cellulo studies are here reported on the very first BODIPY-luminol chemiluminescent resonance energy-transfer (CRET) cassette where the luminol CL agent is covalently linked to the BODIPY energy-transfer acceptor in a molecular dyad. The efficiency of intramolecular CRET investigated for the BODIPY-luminol dyad was found to be 64% resulting in a dual emissive response. Successful in cellulo biochemiluminescence via CRET was achieved in PMA activated splenocytes.
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