Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 51, Issue 3, Pages 630-634Publisher
WILEY
DOI: 10.1002/jhet.1696
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Funding
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- National Natural Science Foundation of China [20802061]
- Qing Lan Project of Jiangsu Education Committee [08QLT001, 10QLD008]
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A mild, green, and facile method for the synthesis of 6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-dione derivatives is described in high yields using ionic liquids as green media. The method involves the reaction of 2-aminobenzamides with 2-formylbenzoic acid catalyzed by iodine and provides a new alkaloid library with potential activity for biomedical screening.
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