Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 45, Issue 5, Pages 1275-1280Publisher
WILEY
DOI: 10.1002/jhet.5570450503
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Funding
- National Nature Science Foundation of China [20472062, 20672079]
- Natural Science Foundation of Jiangsu Province [BK2006048]
- Natural Science Foundation of Jiangsu Education Department [06KJA15007]
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A series of new 3,3'-benzylidenebis(4-hydroxy-6-methylpyridin-2(1H-one) derivatives were synthesized via a three-component reaction of an aldehyde, an aniline or ammonium acetate and 6-methyl-4-hydroxypyran-2-one in ionic liquid. These heterocyclic compounds produced could be conveniently separated from the reaction mixture without any volatile organic solvents, and the ionic liquid could be readily reused without efficiency loss after simple treatment.
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