Molecular mechanism of cholangiocarcinoma carcinogenesis

Molecular aspects of cholangiocarcinoma

(2014) Kaoru Kiguchi   Journal of Hepato-Biliary-Pancreatic Sciences

Risk biomarkers for assessment and chemoprevention of liver fluke-associated cholangiocarcinoma

(2014) Puangrat Yongvanit et al.   Journal of Hepato-Biliary-Pancreatic Sciences

Case series of 17 patients with cholangiocarcinoma among young adult workers of a printing company in Japan

(2014) Shoji Kubo et al.   Journal of Hepato-Biliary-Pancreatic Sciences

Roles of liver fluke infection as risk factor for cholangiocarcinoma

(2014) Paiboon Sithithaworn et al.   Journal of Hepato-Biliary-Pancreatic Sciences

Cholangiocarcinoma

(2014) Nataliya Razumilava et al.   LANCET

Direct targeting of SUZ12/ROCK2 by miR-200b/c inhibits cholangiocarcinoma tumourigenesis and metastasis

(2013) F Peng et al.   BRITISH JOURNAL OF CANCER

KRASandGNASmutations and p53 overexpression in biliary intraepithelial neoplasia and intrahepatic cholangiocarcinomas

(2013) Maylee Hsu et al.   CANCER

miR-204 Inhibits Epithelial to Mesenchymal Transition by Targeting Slug in Intrahepatic Cholangiocarcinoma Cells

(2013) Ying-he Qiu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Inflammation-related DNA damage and expression of CD133 and Oct3/4 in cholangiocarcinoma patients with poor prognosis

(2013) Raynoo Thanan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

(2013) Sumera Rizvi et al.   GASTROENTEROLOGY

Platelet-derived growth factor-D and Rho GTPases regulate recruitment of cancer-associated fibroblasts in cholangiocarcinoma

(2013) Massimiliano Cadamuro et al.   HEPATOLOGY

Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway

(2013) Benjamin Goeppert et al.   HEPATOLOGY

Gankyrin promotes tumor growth and metastasis through activation of IL-6/STAT3 signaling in human cholangiocarcinoma

(2013) Tongsen Zheng et al.   HEPATOLOGY

The frequency of KRAS and BRAF mutations in intrahepatic cholangiocarcinomas and their correlation with clinical outcome

(2013) Scott Robertson et al.   HUMAN PATHOLOGY

15-Hydroxyprostaglandin Dehydrogenase-derived 15-Keto-prostaglandin E2Inhibits Cholangiocarcinoma Cell Growth through Interaction with Peroxisome Proliferator-activated Receptor-γ, SMAD2/3, and TAP63 Proteins

(2013) Dongdong Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch signaling and new therapeutic options in liver disease

(2013) Carola Maria Morell et al.   JOURNAL OF HEPATOLOGY

High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases

(2013) Sejin Jang et al.   MODERN PATHOLOGY

Cholangiocarcinoma among offset colour proof-printing workers exposed to 1,2-dichloropropane and/or dichloromethane

(2013) Shinji Kumagai et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

DNA Damage in Inflammation-Related Carcinogenesis and Cancer Stem Cells

(2013) Shiho Ohnishi et al.   Oxidative Medicine and Cellular Longevity

Transforming Growth Factor β Neutralization Ameliorates Pre-Existing Hepatic Fibrosis and Reduces Cholangiocarcinoma in Thioacetamide-Treated Rats

(2013) Hong Ling et al.   PLoS One

Activation of Notch Signaling Is Required for Cholangiocarcinoma Progression and Is Enhanced by Inactivation of p53 In Vivo

(2013) Mona El Khatib et al.   PLoS One

Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy

(2013) Supak Yothaisong et al.   TUMOR BIOLOGY

MicroRNA-26a Promotes Cholangiocarcinoma Growth by Activating β-catenin

(2012) Jinqiang Zhang et al.   GASTROENTEROLOGY

Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update

(2012) Shahid A Khan et al.   GUT

Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma

(2012) Naoki Oishi et al.   HEPATOLOGY

Recent advances in cancer stem cell research for cholangiocarcinoma

(2012) Toshio Kokuryo et al.   Journal of Hepato-Biliary-Pancreatic Sciences

Preneoplastic conditions underlying bile duct cancer

(2012) Lena Sibulesky et al.   LANGENBECKS ARCHIVES OF SURGERY

Tumor necrosis factor-α (TNF-α) stimulates the epithelial–mesenchymal transition regulator Snail in cholangiocarcinoma

(2012) Anchalee Techasen et al.   MEDICAL ONCOLOGY

S100A9 is a Biliary Protein Marker of Disease Activity in Primary Sclerosing Cholangitis

(2012) Lisa Reinhard et al.   PLoS One

E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma

(2011) K Araki et al.   BRITISH JOURNAL OF CANCER

A Mouse Model of Cholestasis-Associated Cholangiocarcinoma and Transcription Factors Involved in Progression

(2011) Heping Yang et al.   GASTROENTEROLOGY

Cancer surveillance in patients with primary sclerosing cholangitis

(2011) Nataliya Razumilava et al.   HEPATOLOGY

MicroRNA down-regulated in human cholangiocarcinoma control cell cycle through multiple targets involved in the G1/S checkpoint

(2011) Alexandru V. Olaru et al.   HEPATOLOGY

Risk factors for cholangiocarcinoma

(2011) Gia L. Tyson et al.   HEPATOLOGY

Occupational Trichloroethylene Exposure and Renal Carcinoma Risk: Evidence of Genetic Susceptibility by Reductive Metabolism Gene Variants

(2010) L. E. Moore et al.   CANCER RESEARCH

Inhalation carcinogenicity and toxicity of 1,2-dichloropropane in rats

(2010) Yumi Umeda et al.   INHALATION TOXICOLOGY

Epigenetic mechanisms involved in the pathogenesis of hepatobiliary malignancies

(2010) James P Hamilton   Epigenomics

Intrahepatic Cholangiocarcinoma

(2009) Itaru Endo et al.   ANNALS OF SURGERY

Burden of Digestive Diseases in the United States Part III: Liver, Biliary Tract, and Pancreas

(2009) James E. Everhart et al.   GASTROENTEROLOGY

MicroRNAs involved in tumor suppressor and oncogene pathways: Implications for hepatobiliary neoplasia

(2009) Justin L. Mott   HEPATOLOGY

Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6

(2009) Banchob Sripa et al.   HEPATOLOGY

MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3

(2009) Florin M. Selaru et al.   HEPATOLOGY

Preferentially different mechanisms of inactivation of 9p21 gene cluster in liver fluke–related cholangiocarcinoma

(2009) Patcharee Chinnasri et al.   HUMAN PATHOLOGY

Risk of liver cancer and exposure to organic solvents and gasoline vapors among Finnish workers

(2009) Marja-Liisa Lindbohm et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor Necrosis Factor-α Regulates Transforming Growth Factor-β-dependent Epithelial-Mesenchymal Transition by Promoting Hyaluronan-CD44-Moesin Interaction

(2009) Eri Takahashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Risk factors for intrahepatic cholangiocarcinoma: a possible role of hepatitis B virus

(2009) M. Tanaka et al.   JOURNAL OF VIRAL HEPATITIS

Occupational Exposure to Solvents and Risk of Non-Hodgkin Lymphoma in Connecticut Women

(2008) R. Wang et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Over-expression of polycomb group protein EZH2 relates to decreased expression of p16INK4a in cholangiocarcinogenesis in hepatolithiasis

(2008) M Sasaki et al.   JOURNAL OF PATHOLOGY

The cancer stem cell hypothesis: in search of definitions, markers and relevance

(2008) Michail Shipitsin et al.   LABORATORY INVESTIGATION

Pancreaticobiliary maljunction and carcinogenesis to biliary and pancreatic malignancy

(2008) Takahiko Funabiki et al.   LANGENBECKS ARCHIVES OF SURGERY