Molecular diagnosis of intrahepatic cholangiocarcinoma

Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma

(2014) Alexandra R. Grassian et al.   CURRENT OPINION IN GASTROENTEROLOGY

Analysis of U2 Small Nuclear RNA Fragments in the Bile Differentiates Cholangiocarcinoma from Primary Sclerosing Cholangitis and Other Benign Biliary Disorders

(2014) Alexander Baraniskin et al.   DIGESTIVE DISEASES AND SCIENCES

Extracellular vesicle noncoding RNA: New players in the diagnosis and pathogenesis of cholangiocarcinoma

(2014) Tushar Patel   HEPATOLOGY

Human bile contains MicroRNA-laden extracellular vesicles that can be used for cholangiocarcinoma diagnosis

(2014) Ling Li et al.   HEPATOLOGY

Genomic and transcriptional alterations of cholangiocarcinoma

(2014) Takeshi Ito et al.   Journal of Hepato-Biliary-Pancreatic Sciences

New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation Sequencing

(2014) J. S. Ross et al.   ONCOLOGIST

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

(2014) Mitesh J. Borad et al.   PLoS Genetics

Expression of Smad7 in Cholangiocarcinoma: Prognostic Significance and Implications for Tumor Metastasis

(2013) Qiang Huang et al.   Asian Pacific Journal of Cancer Prevention

KRASandGNASmutations and p53 overexpression in biliary intraepithelial neoplasia and intrahepatic cholangiocarcinomas

(2013) Maylee Hsu et al.   CANCER

The Prognostic Significance and Therapeutic Potential of Hedgehog Signaling in Intrahepatic Cholangiocellular Carcinoma

(2013) L. Tang et al.   CLINICAL CANCER RESEARCH

Aberrant expression of GATA binding protein 6 correlates with poor prognosis and promotes metastasis in cholangiocarcinoma

(2013) Feng Tian et al.   EUROPEAN JOURNAL OF CANCER

Integrative Molecular Analysis of Intrahepatic Cholangiocarcinoma Reveals 2 Classes That Have Different Outcomes

(2013) Daniela Sia et al.   GASTROENTEROLOGY

Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma

(2013) Yasuhito Arai et al.   HEPATOLOGY

The frequency of KRAS and BRAF mutations in intrahepatic cholangiocarcinomas and their correlation with clinical outcome

(2013) Scott Robertson et al.   HUMAN PATHOLOGY

Epithelial–mesenchymal transition phenotypes are associated with patient survival in intrahepatic cholangiocarcinoma

(2013) Mi Jin Gu et al.   JOURNAL OF CLINICAL PATHOLOGY

Clinicopathological significance of S100 protein expression in cholangiocarcinoma

(2013) Yasunori Sato et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Clinicopathological and prognostic significances of EGFR, KRAS and BRAF mutations in biliary tract carcinomas in Taiwan

(2013) Yu-Ting Chang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Glycoproteomics-based cancer marker discovery adopting dual enrichment with Wisteria floribunda agglutinin for high specific glyco-diagnosis of cholangiocarcinoma

(2013) Atsushi Matsuda et al.   Journal of Proteomics

Intrahepatic Cholangiocarcinoma: Management Options and Emerging Therapies

(2013) Rebecca M. Dodson et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases

(2013) Sejin Jang et al.   MODERN PATHOLOGY

Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers

(2013) Waraporn Chan-on et al.   NATURE GENETICS

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

(2013) Yuchen Jiao et al.   NATURE GENETICS

Cholangiocarcinoma among offset colour proof-printing workers exposed to 1,2-dichloropropane and/or dichloromethane

(2013) Shinji Kumagai et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies

(2013) D Sia et al.   ONCOGENE

Prognostic Significance of Capn4 Overexpression in Intrahepatic Cholangiocarcinoma

(2013) Chi Zhang et al.   PLoS One

Overexpression of microRNA-21 regulating PDCD4 during tumorigenesis of liver fluke-associated cholangiocarcinoma contributes to tumor growth and metastasis

(2013) P. Chusorn et al.   TUMOR BIOLOGY

Identification of Targetable FGFR Gene Fusions in Diverse Cancers

(2013) Yi-Mi Wu et al.   Cancer Discovery

Differential Expression of Fascin, E-cadherin and Vimentin: Proteins Associated With Survival of Cholangiocarcinoma Patients

(2012) Xianhai Mao et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Intratumoral IL-17+ Cells and Neutrophils show Strong Prognostic Significance in Intrahepatic Cholangiocarcinoma

(2012) Fang-Ming Gu et al.   ANNALS OF SURGICAL ONCOLOGY

Expression of Mesenchymal Markers Vimentin and Fibronectin: The Clinical Significance in Esophageal Squamous Cell Carcinoma

(2012) Tomoya Sudo et al.   ANNALS OF SURGICAL ONCOLOGY

High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery

(2012) Ruo-Yu Shi et al.   CANCER

Serum α1β-glycoprotein and afamin ratio as potential diagnostic and prognostic markers in cholangiocarcinoma

(2012) Arthit Tolek et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Down-regulation of miR-214 contributes to intrahepatic cholangiocarcinoma metastasis by targeting Twist

(2012) Bin Li et al.   FEBS Journal

Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma

(2012) Naoki Oishi et al.   HEPATOLOGY

Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma

(2012) Benjamin R. Kipp et al.   HUMAN PATHOLOGY

Are common factors involved in the pathogenesis of primary liver cancers? A meta-analysis of risk factors for intrahepatic cholangiocarcinoma

(2012) William C. Palmer et al.   JOURNAL OF HEPATOLOGY

BAP1 loss defines a new class of renal cell carcinoma

(2012) Samuel Peña-Llopis et al.   NATURE GENETICS

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

(2012) P Wang et al.   ONCOGENE

Pathobiological Implications of MUC16/CA125 Expression in Intrahepatic Cholangiocarcinoma-Mass Forming Type

(2012) Michiyo Higashi et al.   PATHOBIOLOGY

Comparative Proteomic Profiling of Human Bile Reveals SSP411 as a Novel Biomarker of Cholangiocarcinoma

(2012) Jian Shen et al.   PLoS One

Platelet-derived growth factor may be a potential diagnostic and prognostic marker for cholangiocarcinoma

(2012) Sirintip Boonjaraspinyo et al.   TUMOR BIOLOGY

Clinicopathological and prognostic significance of epithelial mesenchymal transition-related protein expression in intrahepatic cholangiocarcinoma

(2012) Xing Yao et al.   OncoTargets and Therapy

Prognostic significance of Beclin 1 in intrahepatic cholangiocellular carcinoma

(2011) Li-Wei Dong et al.   Autophagy

Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors

(2011) Jesper B. Andersen et al.   GASTROENTEROLOGY

Nuclear expression of S100A4 calcium-binding protein increases cholangiocarcinoma invasiveness and metastasization

(2011) Luca Fabris et al.   HEPATOLOGY

Expression and prognostic significance of cancer-testis antigens (CTA) in intrahepatic cholagiocarcinoma

(2011) Jin-xue Zhou et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

(2011) M Fernanda Amary et al.   JOURNAL OF PATHOLOGY

The expression of phospho-AKT1 and phospho-MTOR is associated with a favorable prognosis independent of PTEN expression in intrahepatic cholangiocarcinomas

(2011) Dakeun Lee et al.   MODERN PATHOLOGY

Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR-146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance

(2011) Andreas Karakatsanis et al.   MOLECULAR CARCINOGENESIS

Cholangiocarcinoma—controversies and challenges

(2011) Tushar Patel   Nature Reviews Gastroenterology & Hepatology

Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping

(2011) D. R. Borger et al.   ONCOLOGIST

Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-β1/Snail Activation Aggravates Invasive Growth of Cholangiocarcinoma

(2010) Yasunori Sato et al.   AMERICAN JOURNAL OF PATHOLOGY

Value of indocyanine green clearance of the future liver remnant in predicting outcome after resection for biliary cancer

(2010) Y. Yokoyama et al.   BRITISH JOURNAL OF SURGERY

Overexpression of CD151 as an adverse marker for intrahepatic cholangiocarcinoma patients

(2010) Xiao-Yong Huang et al.   CANCER

ALK Inhibition for Non-Small Cell Lung Cancer: From Discovery to Therapy in Record Time

(2010) David E. Gerber et al.   CANCER CELL

Wisteria floribunda agglutinin-positive mucin 1 is a sensitive biliary marker for human cholangiocarcinoma

(2010) Atsushi Matsuda et al.   HEPATOLOGY

Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker

(2010) Kusumawadee Utispan et al.   Molecular Cancer

Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer

(2010) Juan Valle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Radioembolization of Liver Tumors With Yttrium-90 Microspheres

(2010) Hojjat Ahmadzadehfar et al.   SEMINARS IN NUCLEAR MEDICINE

Prospective study of MMP7 serum levels in the diagnosis of cholangiocarcinoma

(2010) Kawin Leelawat   WORLD JOURNAL OF GASTROENTEROLOGY

MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types

(2009) Richard Hummel et al.   EUROPEAN JOURNAL OF CANCER

IMP3 expression in lesions of the biliary tract: a marker for high-grade dysplasia and an independent prognostic factor in bile duct carcinomas

(2009) Marc-Oliver Riener et al.   HUMAN PATHOLOGY

Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder

(2009) Nafis Shafizadeh et al.   HUMAN PATHOLOGY

Expression and Prognostic Value of PRL-3 in Human Intrahepatic Cholangiocarcinoma

(2009) Yijun Xu et al.   PATHOLOGY & ONCOLOGY RESEARCH

Stereotactic body radiotherapy for unresectable cholangiocarcinoma

(2009) Neil Kopek et al.   RADIOTHERAPY AND ONCOLOGY

Clinical Significance of Cell Cycle–and Apoptosis-Related Markers in Biliary Tract Cancer

(2008) Eva Karamitopoulou et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Prognostic Significance of CD44s Expression in Biliary Tract Cancers

(2008) Sang Min Lee et al.   ANNALS OF SURGICAL ONCOLOGY

Immunohistochemically Detected Expression of p27Kip1 and Skp2 Predicts Survival in Patients with Intrahepatic Cholangiocarcinomas

(2008) Nozomi Hashimoto et al.   ANNALS OF SURGICAL ONCOLOGY

Role of overexpression of CD151 and/or c-Met in predicting prognosis of hepatocellular carcinoma

(2008) Ai-Wu Ke et al.   HEPATOLOGY

Fascin overexpression is involved in carcinogenesis and prognosis of human intrahepatic cholangiocarcinoma: immunohistochemical and molecular analysis

(2008) Tomohiro Iguchi et al.   HUMAN PATHOLOGY

Lymphatic spread is related to VEGF-C expression and D2-40-positive myofibroblasts in intrahepatic cholangiocarcinoma

(2008) Shinichi Aishima et al.   MODERN PATHOLOGY

Systemic Therapy for Biliary Tract Cancers

(2008) A. F. Hezel et al.   ONCOLOGIST

Reduced expression of P120 catenin in cholangiocarcinoma correlated with tumor clinicopathologic parameters

(2008) Bo Zhai et al.   WORLD JOURNAL OF GASTROENTEROLOGY