Inhibition of protein kinase CK2 with the clinical-grade small ATP-competitive compound CX-4945 or by RNA interference unveils its role in acute myeloid leukemia cell survival, p53-dependent apoptosis and daunorubicin-induced cytotoxicity

Title
Inhibition of protein kinase CK2 with the clinical-grade small ATP-competitive compound CX-4945 or by RNA interference unveils its role in acute myeloid leukemia cell survival, p53-dependent apoptosis and daunorubicin-induced cytotoxicity
Authors
Keywords
Acute myeloid leukemia, Kinase inhibitors, Protein kinase CK2, CX-4945, p53, Daunorubicin, STAT3, Apoptosis
Journal
Journal of Hematology & Oncology
Volume 6, Issue 1, Pages 78
Publisher
Springer Nature
Online
2013-10-13
DOI
10.1186/1756-8722-6-78

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