Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients
Authors
Keywords
-
Journal
Journal of Hematology & Oncology
Volume 5, Issue 1, Pages 5
Publisher
Springer Nature
Online
2012-03-08
DOI
10.1186/1756-8722-5-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The prognostic significance of IDH2 mutations in AML depends on the location of the mutation
- (2011) C. L. Green et al. BLOOD
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Rapid and reliable detection of IDH1 R132 mutations in acute myeloid leukemia using high-resolution melting curve analysis
- (2011) Jiang Lin et al. CLINICAL BIOCHEMISTRY
- Current findings for recurring mutations in acute myeloid leukemia
- (2011) Shinichiro Takahashi Journal of Hematology & Oncology
- Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications
- (2011) Shinichiro Takahashi Journal of Hematology & Oncology
- IDH1 and IDH2 mutations in pediatric acute leukemia
- (2011) A K Andersson et al. LEUKEMIA
- Some novel features of IDH1-mutated acute myeloid leukemia revealed in Chinese patients
- (2011) Yiqun Zhang et al. LEUKEMIA RESEARCH
- Acute Myeloid Leukemia WithIDH1orIDH2Mutation
- (2010) Keyur P. Patel et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders
- (2010) Yang Zou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status
- (2010) S. Schnittger et al. BLOOD
- Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value
- (2010) S. Abbas et al. BLOOD
- Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia
- (2010) F. Thol et al. BLOOD
- Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation
- (2010) W. C. Chou et al. BLOOD
- The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
- (2010) Patrick S. Ward et al. CANCER CELL
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
- IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis
- (2010) F. Thol et al. HAEMATOLOGICA
- Prognostic Impact of Isocitrate Dehydrogenase Enzyme Isoforms 1 and 2 Mutations in Acute Myeloid Leukemia: A Study by the Acute Leukemia French Association Group
- (2010) Nicolas Boissel et al. JOURNAL OF CLINICAL ONCOLOGY
- Impact of IDH1 R132 Mutations and an IDH1 Single Nucleotide Polymorphism in Cytogenetically Normal Acute Myeloid Leukemia: SNP rs11554137 Is an Adverse Prognostic Factor
- (2010) Katharina Wagner et al. JOURNAL OF CLINICAL ONCOLOGY
- IDH1andIDH2Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
- (2010) Guido Marcucci et al. JOURNAL OF CLINICAL ONCOLOGY
- IDH1 and IDH2 Mutations Are Frequent Genetic Alterations in Acute Myeloid Leukemia and Confer Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia With NPM1 Mutation Without FLT3 Internal Tandem Duplication
- (2010) Peter Paschka et al. JOURNAL OF CLINICAL ONCOLOGY
- Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
- (2010) Stefan Gross et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Recurrent IDH mutations in high-risk myelodysplastic syndrome or acute myeloid leukemia with isolated del(5q)
- (2010) A Pardanani et al. LEUKEMIA
- Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study
- (2010) P A Ho et al. LEUKEMIA
- IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis
- (2010) A Tefferi et al. LEUKEMIA
- IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms
- (2010) A Pardanani et al. LEUKEMIA
- Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms
- (2010) O Kosmider et al. LEUKEMIA
- Somatic Mutations ofIDH1andIDH2in the Leukemic Transformation of Myeloproliferative Neoplasms
- (2010) Anthony Green et al. NEW ENGLAND JOURNAL OF MEDICINE
- IDH mutations in glioma and acute myeloid leukemia
- (2010) Lenny Dang et al. TRENDS IN MOLECULAR MEDICINE
- IDH1mutations at residue p.R132 (IDH1R132) occur frequently in high-grade gliomas but not in other solid tumors
- (2009) Fonnet E. Bleeker et al. HUMAN MUTATION
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
- (2009) Elaine R. Mardis et al. NEW ENGLAND JOURNAL OF MEDICINE
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1
- (2009) S. Zhao et al. SCIENCE
- Nucleophosmin mutation in Southeast Asian acute myeloid leukemia: eight novel variants, FLT3 coexistence and prognostic impact of NPM1/FLT3 mutations
- (2008) C. Boonthimat et al. HAEMATOLOGICA
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started