Review
Clinical Neurology
Paul G. Harch
Summary: This systematic review examines the evidence for hyperbaric oxygen therapy in Persistent Postconcussion Syndrome using a dose-analysis based on the scientific definition of hyperbaric oxygen therapy. The results suggest that hyperbaric oxygen therapy at 1.5 ATA can significantly improve symptoms and cognitive function in patients with mild traumatic brain injury Persistent Postconcussion Syndrome, with positive and negative results found at different doses of oxygen and pressure.
FRONTIERS IN NEUROLOGY
(2022)
Review
Clinical Neurology
Martijn de Neeling, Dirk Liessens, Bart Depreitere
Summary: Mild traumatic brain injury (mTBI) has a high incidence worldwide, and long-term persistent postconcussion symptoms (PPCS) are predicted by psychological and psychiatric factors. Anxiety, depressive symptoms, and emotional distress early after injury can predict PPCS burden and functional outcome. Coping styles, preinjury psychiatric disorders and mental health also correlate with PPCS burden and functional outcome.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Psychology, Multidisciplinary
Ashley N. Clausen, Heather C. Bouchard, Kathleen A. Welsh-Bohmer, Rajendra A. Morey
Summary: This study compared the chronic effects of combat-related blast mTBI and subconcussive blast exposure on neuropsychological performance in Veterans. Results showed that Veterans with combat-related blast mTBI exhibited significantly slower processing speed compared to controls, even after controlling for PTSD and depressive symptoms. However, there were no significant differences in cognition between subconcussive and control groups, or between subconcussive and combat-related blast mTBI groups, suggesting that neurocognitive assessment may not be sensitive enough to detect the long-term effects of subconcussive blast exposure.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Neurosciences
Jill Daugherty, Kelly Sarmiento, Matthew Breiding
Summary: This study examines how the wording of questions can influence the reporting of traumatic brain injury (TBI). The results show that a greater percentage of respondents reported a lifetime history of concussion compared to mild TBI, suggesting that the terminology used can impact reporting.
Review
Biochemistry & Molecular Biology
William Torregrossa, Michele Torrisi, Rosaria De Luca, Carmela Casella, Carmela Rifici, Mirjam Bonanno, Rocco Salvatore Calabro
Summary: Traumatic brain injury is damage to the brain occurring after birth, resulting in deterioration of cognitive, behavioural, and emotional functions. Neuropsychological evaluation can assist clinicians in assessing the patient's condition, reaching differential diagnoses, and developing intervention strategies. However, it is difficult to determine the most suitable assessment tool for different brain injury conditions considering the various rating scales available.
Article
Clinical Neurology
Kaisa Maki, Taina Nybo, Marja Hietanen, Antti Huovinen, Ivan Marinkovic, Harri Isokuortti, Susanna Melkas
Summary: Perceived injustice is associated with self-reported symptoms in patients with mild traumatic brain injury (mTBI). Our results suggest that perceived injustice could be a relevant construct to consider in clinical management of patients with mTBI, and it could be a potential target for psychological interventions promoting recovery after mTBI.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2022)
Article
Clinical Neurology
Barry M. Miskin, Lee A. Fox, Hussam Abou-Al-Shaar, Othman Bin-Alamer, Aaron Goertz, Conner T. Lipin, Nicole Fertig, Nevada Cox
Summary: This study evaluated the safety and outcomes of hyperbaric oxygen therapy (HBOT) in managing the long-term sequelae of traumatic brain injury (TBI). The results showed that TBI patients who underwent 40 sessions of HBOT at 1.5 atmosphere absolute experienced significant improvements in cognitive and physical function, as well as increased cerebral blood flow and oxygen metabolism. HBOT was considered a safe and effective modality in the treatment of the long-term sequelae of TBI.
WORLD NEUROSURGERY
(2023)
Article
Multidisciplinary Sciences
Mohammed M. Alnawmasi, Sieu K. Khuu
Summary: This study investigated the impact of TBI on the allocation and maintenance of visual attention to multiple moving targets using a multiple object tracking task. The results showed that patients with mild TBI had greater deficits in maintaining visual attention and detecting targets, particularly when the tracking load and distraction increased.
SCIENTIFIC REPORTS
(2022)
Review
Critical Care Medicine
David Hacker, Christopher A. Jones, Eyrsa Yasin, Sophie Preece, Holly Davies, Andrew Hawkins, Antonio Belli, Emily Paton
Summary: Cognitive outcomes were compared between mild traumatic brain injury (mTBI) with positive brain imaging (complicated mTBI) and mTBI with normal imaging (uncomplicated mTBI) as well as moderate to severe TBI. The findings showed that complicated mTBI had poorer cognitive outcomes than uncomplicated mTBI, but the deficits were not as severe as in moderate-severe TBI. The deficits in complicated mTBI were present in processing speed, memory, executive function, and language beyond 3 months post-injury.
JOURNAL OF NEUROTRAUMA
(2023)
Article
Psychology, Clinical
Josh W. Faulkner, Deborah L. Snell, Alice Theadom, Susan Mahon, Suzanne Barker-Collo
Summary: The study found that psychological flexibility significantly affects postconcussion symptoms and functional status in individuals with mTBI, serving as an important treatment target in mTBI interventions. Researchers suggest that psychological flexibility is a psychological mechanism that contributes to recovery outcomes in individuals with mTBI.
REHABILITATION PSYCHOLOGY
(2021)
Article
Medicine, General & Internal
Sophia Wagberg, Britt-Marie Stalnacke, Beatrice M. M. Magnusson
Summary: This study evaluates post-TBI symptoms and disabilities seven to eight years after mild TBI (mTBI), showing that women and individuals with repeated TBI experience more severe symptoms and functional decline. These findings have implications for clinical practice and research, and should be considered in rehabilitation and follow-up plans.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Anesthesiology
Cayden Peixoto, Derrick Matthew Buchanan, Richard Nahas
Summary: Missed diagnosis of mTBI is common in patients presenting to the ED after MVC, and these patients are at risk of developing chronic pain syndromes. Better screening for mTBI is needed, especially in patients with loss of consciousness, altered mental state, posttraumatic amnesia, or postinjury headache, who are at increased risk of PCS.
Article
Cell Biology
Ruslan Prus, Olena Appelhans, Maksim Logash, Petro Pokotylo, Grzegorz Jozef Nowicki, Barbara Slusarska
Summary: Traumatic brain injury is a serious issue in modern medicine, with our study showing that mild TBI causes different histological changes in the livers of adult and juvenile rats. The most significant changes were observed on days 5-7, with compensatory phenomena prevailing on days 14-21 in both groups.
Article
Behavioral Sciences
Chandni Sheth, Jadwiga Rogowska, Margaret Legarreta, Erin McGlade, Deborah Yurgelun-Todd
Summary: The study revealed increased connectivity between the ACC and other brain regions in Veterans with mTBI, consistent with previous research findings. This may explain enhanced top-down control networks to compensate for microstructural damage post-mTBI.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Multidisciplinary Sciences
Eli Fried, Uri Balla, Merav Catalogna, Eran Kozer, Adi Oren-Amit, Amir Hadanny, Shai Efrati
Summary: This study aimed to evaluate the prevalence of persistent post-concussion syndrome (PPCS) in children after mild traumatic brain injury (mTBI) and identify high-risk factors. The results showed that 25% of children may suffer from PPCS, but it is often underdiagnosed in the pediatric population. Screening guidelines should be implemented to identify and treat these children in a timely manner.
SCIENTIFIC REPORTS
(2022)
