Article
Clinical Neurology
Richard Menger, Brett Youngerman, Rimal Hanif Dossani, Jakub Godzik, Steven Tenny, Jeffrey Cozzens, Nitin Agarwal, Bharat Guthikonda, Kristopher T. Kimmell, Clemens Schirmer, Joshua M. Rosenow, Luis M. Tumialan
Summary: Practicing neurosurgery in 2021 requires a detailed understanding of coding and reimbursement mechanisms, with a particular focus on the nuances of hospital reimbursement. This knowledge is crucial for neurosurgeons who may become hospital employees in the future.
WORLD NEUROSURGERY
(2021)
Article
Oncology
Brian Mitzman, Xuechen Wang, Ben Haaland, Thomas K. K. Varghese Jr
Summary: Transparency in physician billing is lacking in the US, with wide variations in charges. This study evaluated Medicare charges for minimally invasive lobectomy to understand national billing practices and factors associated with higher charges.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Review
Critical Care Medicine
Priyanka Heeru Teckchandani, Kimberly Kay Truong, Danielle Zezoff, William J. Healy, Rami N. Khayat
Summary: Central sleep apnea (CSA) frequently coexists with heart failure and atrial fibrillation. A novel transvenous phrenic nerve stimulation (TPNS) system has been approved for the treatment of CSA. However, patient access to this therapy remains limited and requires specialized programs and support from healthcare systems.
Article
Critical Care Medicine
J. Christian Bruce, Anna M. McGregor, Hector Garcia, Kiana Banafshay, Emily Brumfield, Alan Pang, Deepak Bharadia, John Griswold
Summary: Documentation by healthcare providers is crucial for appropriate reimbursement. Inadequate medical decision-making documentation can result in revenue loss. To tackle this issue, resources were created to improve documentation quality and increase revenue in a burn center.
Article
Clinical Neurology
Terry D. Fife, Alan L. Desmond, Kevin A. Kerber
Summary: Coding and insurance reimbursement in the US healthcare system are subject to periodic modifications, with changes in E/M codes and differences in coding for diagnostic vestibular function test procedures. The article outlines the current state of coding and reimbursement by CMS for vestibular procedures, including the addition of new codes and elimination of previous codes.
OTOLOGY & NEUROTOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
George Wu, Colin S. Segovis, Lauren P. Nicola, Melissa M. Chen
Summary: Payment and coverage policy is a major obstacle in the widespread adoption of new procedures and technologies like artificial intelligence algorithms. However, the noninvasive assessment of coronary fractional flow reserve, an AI imaging algorithm, will successfully achieve reimbursement through multiple pathways of CMS payment mechanisms in 2024. Understanding the payment process of this AI algorithm helps comprehend the challenges CMS faces in paying for new services and innovation in the United States.
JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY
(2023)
Article
Otorhinolaryngology
David A. Kasle, Sina J. Torabi, Emily L. Savoca, Michael Lerner, R. Peter Manes
Summary: This study aimed to analyze the reimbursement trends of FEES/FEESST and MBS from 2003 to 2018, finding a steady increase in both the number and reimbursement amount of FEES/FEESST. The majority of high-volume FEES/FEESST billers were otolaryngologists and independently billing SLPs.
Article
Economics
Nada Wasi, Jirawat Panpiemras, Wanwiphang Manachotphong
Summary: This study found that the new billing process of the Thai Civil Servant Medical Benefit Scheme has positive impacts on outpatient care utilization, affecting both visiting rates and treatment intensity. These impacts are moderate yet persistent, and can be sensitive to model specifications. Patients with lower utilization rates before the change tend to increase their healthcare utilization more proportionally.
OXFORD BULLETIN OF ECONOMICS AND STATISTICS
(2021)
Article
Clinical Neurology
Ryan G. Chiu, Neha Siddiqui, Ravi S. Nunna, Saavan Patel, Clayton L. Rosinski, Anisse N. Chaker, Jonathan G. Hobbs, Ankit Mehta
Summary: The study found that work RVUs for neurosurgical procedures are highly correlated with objective measures of surgical complexity, with few exceptions. By analyzing multiple factors, undervalued and overvalued surgical procedures can be identified.
WORLD NEUROSURGERY
(2021)
Article
Ophthalmology
Sonia C. Francone, Don T. Pham, Masumi G. Asahi, Haig Pakhchanian, Rahul Raiker, Stephen Lesche, Aseef Ahmed, David Belyea
Summary: This study investigates the reimbursement trends for common glaucoma procedures in US Medicare from 2000 to 2020. The results show a significant decline in reimbursement over the 20-year period.
JOURNAL OF GLAUCOMA
(2022)
Article
Mathematics, Applied
Turki Alsuraiheed, Elif Segah Oztas, Shakir Ali, Merve Bulut Yilgor
Summary: This study presents a novel approach for discovering reversible codes over rings using the concept of r-glifted polynomials. By extending this methodology to the domain of DNA codes, a correspondence is established between 4t-bases of DNA and elements within a specific ring. The challenges of reversibility and complementarity in DNA codes over this ring are successfully addressed.
Article
Multidisciplinary Sciences
Daniel L. Barabasi, Daniel Czegel
Summary: This passage discusses a method of network connection based on identity-dependent compatibility rules, deriving from genetic principles to generate specific topologies and various network structures. It also explores the characteristics of Random Genetic networks and their behavior under targeted attacks, serving as a relevant null-model for social and biological systems.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Shayan Owji, Michael Tassavor, Joseph Han, Alexandra Golant, Cula Svidzinski, Jonathan Ungar
Summary: The aim of the study was to evaluate the impact of an interventional coding curriculum on dermatology residents' billing accuracy. While there was no improvement in E/M coding, significant improvements were seen in the usage of procedural codes and modifiers after the intervention.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Computer Science, Interdisciplinary Applications
Mark P. J. van der Loo
Summary: By customizing code evaluation, using local masking, and leveraging local side effects, we can extract and process secondary information from running R scripts. This approach allows users to create and control secondary flows of information with minimal impact on their workflow and without global side effects.
Article
Oncology
Huma Q. Rana, Lindsay Kipnis, Kristin Hehir, Angel Cronin, Tim Jaung, Samantha M. Stokes, Fatemeh Fekrmandi, Donna Vatnick, Ursula A. Matulonis, Judy E. Garber, Alexi A. Wright
Summary: The study found that embedding a genetic counselor in a medical and gynecologic oncology clinic significantly increased genetic testing rates and improved timeliness for ovarian cancer patients, leading to higher adherence to guideline recommendations.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Oncology
Yingchang Lu, Sun-Seog Kweon, Qiuyin Cai, Chizu Tanikawa, Xiao-Ou Shu, Wei-Hua Jia, Yong-Bing Xiang, Jeroen R. Huyghe, Tabitha A. Harrison, Jeongseon Kim, Aesun Shin, Dong-Hyun Kim, Keitaro Matsuo, Sun Ha Jee, Xingyi Guo, Wanqing Wen, Jiajun Shi, Bingshan Li, Nan Wang, Min-Ho Shin, Hong-Lan Li, Zefang Ren, Jae Hwan Oh, Isao Oze, Yoon-Ok Ahn, Keum Ji Jung, Jing Gao, Yu-Tang Gao, Zhi-Zhong Pan, Yoichiro Kamatani, Andrew T. Chan, Andrea Gsur, Jochen Hampe, Loic Le Marchand, Li Li, Annika Lindblom, Victor Moreno, Polly A. Newcomb, Kenneth Offit, Paul D. P. Pharoah, Franzel J. B. Van Duijnhoven, Bethany Van Guelpen, Pavel Vodicka, Stephanie J. Weinstein, Alicja Wolk, Anna H. Wu, Li Hsu, Yi-Xin Zeng, Jirong Long, Ulrike Peters, Koichi Matsuda, Wei Zheng
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2020)
Article
Gastroenterology & Hepatology
Amanda Phipps, Elizabeth Alwers, Tabitha Harrison, Barbara Banbury, Hermann Brenner, Peter T. Campbell, Jenny Chang-Claude, Daniel Buchanan, Andrew T. Chan, Alton B. Farris, Jane C. Figueiredo, Steven Gallinger, Graham G. Giles, Mark Jenkins, Roger L. Milne, Polly A. Newcomb, Martha L. Slattery, Mingyang Song, Shuji Ogino, Syed H. Zaidi, Michael Hoffmeister, Ulrike Peters
Article
Oncology
Peter T. Campbell, Yi Lin, Stephanie A. Bien, Jane C. Figueiredo, Tabitha A. Harrison, Mark A. Guinter, Sonja Berndt, Hermann Brenner, Andrew T. Chan, Jenny Chang-Claude, Steven J. Gallinger, Susan M. Gapstur, Graham G. Giles, Edward Giovannucci, Stephen B. Gruber, Marc Gunter, Michael Hoffmeister, Eric J. Jacobs, Mark A. Jenkins, Loic Le Marchand, Li Li, John R. McLaughlin, Neil Murphy, Roger L. Milne, Polly A. Newcomb, Christina Newton, Shuji Ogino, John D. Potter, Gad Rennert, Hedy S. Rennert, Jennifer Robinson, Lori C. Sakoda, Martha L. Slattery, Yiqing Song, Emily White, Michael O. Woods, Graham Casey, Li Hsu, Ulrike Peters
Summary: The study found that every 5kg/m(2) increase in BMI is associated with higher risks of colorectal cancer, with women being less affected than men. There is a potential interaction between BMI and a SMAD7 gene variant that may influence colorectal cancer risk specifically in women.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2021)
Article
Oncology
Hang Yin, Sheetal Hardikar, Sara Lindstroem, Li Hsu, Kristin E. Anderson, Barbara L. Banbury, Sonja Berndt, Andrew T. Chan, Edward L. Giovanucci, Tabitha A. Harrison, Amit D. Joshi, Hongmei Nan, John D. Potter, Lori C. Sakoda, Martha L. Slattery, Robert E. Schoen, Emily White, Ulrike Peters, Polly A. Newcomb
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2020)
Article
Multidisciplinary Sciences
Syed H. Zaidi, Tabitha A. Harrison, Amanda Phipps, Robert Steinfelder, Quang M. Trinh, Conghui Qu, Barbara L. Banbury, Peter Georgeson, Catherine S. Grasso, Marios Giannakis, Jeremy B. Adams, Elizabeth Alwers, Efrat L. Amitay, Richard T. Barfield, Sonja Berndt, Ivan Borozan, Hermann Brenner, Stefanie Brezina, Daniel D. Buchanan, Yin Cao, Andrew T. Chan, Jenny Chang-Claude, Charles M. Connolly, David A. Drew, Alton Brad Farris, Jane C. Figueiredo, Amy J. French, Charles S. Fuchs, Levi A. Garraway, Steve Gruber, Mark A. Guinter, Stanley R. Hamilton, Sophia Harlid, Lawrence E. Heisler, Akihisa Hidaka, John L. Hopper, Wen-Yi Huang, Jeroen R. Huyghe, Mark A. Jenkins, Paul M. Krzyzanowski, Mathieu Lemire, Yi Lin, Xuemei Luo, Elaine R. Mardis, John D. McPherson, Jessica K. Miller, Victor Moreno, Xinmeng Jasmine Mu, Reiko Nishihara, Nickolas Papadopoulos, Danielle Pasternack, Michael J. Quist, Adilya Rafikova, Emma E. G. Reid, Eve Shinbrot, Brian H. Shirts, Lincoln D. Stein, Cherie D. Teney, Lee Timms, Caroline Y. Um, Bethany Van Guelpen, Megan Van Tassel, Xiaolong Wang, David A. Wheeler, Christina K. Yung, Li Hsu, Shuji Ogino, Andrea Gsur, Polly A. Newcomb, Steven Gallinger, Michael Hoffmeister, Peter T. Campbell, Stephen N. Thibodeau, Wei Sun, Thomas J. Hudson, Ulrike Peters
NATURE COMMUNICATIONS
(2020)
Article
Oncology
Akihisa Hidaka, Tabitha A. Harrison, Yin Cao, Lori C. Sakoda, Richard Barfield, Marios Giannakis, Mingyang Song, Amanda Phipps, Jane C. Figueiredo, Syed H. Zaidi, Amanda E. Toland, Efrat L. Amitay, Sonja Berndt, Ivan Borozan, Andrew T. Chan, Steven Gallinger, Marc J. Gunter, Mark A. Guinter, Sophia Harlid, Heather Hampel, Mark A. Jenkins, Yi Lin, Victor Moreno, Polly A. Newcomb, Reiko Nishihara, Shuji Ogino, Mireia Obon-Santacana, Patrick S. Parfrey, John D. Potter, Martha L. Slattery, Robert S. Steinfelder, Caroline Y. Um, Xiaoliang Wang, Michael O. Woods, Bethany Van Guelpen, Stephen N. Thibodeau, Michael Hoffmeister, Wei Sun, Li Hsu, Daniel D. Buchanan, Peter T. Campbell, Ulrike Peters
Article
Gastroenterology & Hepatology
Xingyi Guo, Weiqiang Lin, Wanqing Wen, Jeroen Huyghe, Stephanie Bien, Qiuyin Cai, Tabitha Harrison, Zhishan Chen, Conghui Qu, Jiandong Bao, Jirong Long, Yuan Yuan, Fangqin Wang, Mengqiu Bai, Goncalo R. Abecasis, Demetrius Albanes, Sonja Berndt, Stephane Bezieau, D. Timothy Bishop, Hermann Brenner, Stephan Buch, Andrea Burnett-Hartman, Peter T. Campbell, Sergi Castellvi-Bel, Andrew T. Chan, Jenny Chang-Claude, Stephen J. Chanock, Sang Hee Cho, David Conti, Albert de la Chapelle, Edith J. M. Feskens, Steven J. Gallinger, Graham G. Giles, Phyllis J. Goodman, Andrea Gsur, Mark Guinter, Marc J. Gunter, Jochen Hampe, Heather Hampel, Richard B. Hayes, Michael Hoffmeister, Ellen Kampman, Hyun Min Kang, Temitope O. Keku, Hyeong Rok Kim, Loic Le Marchand, Soo Chin Lee, Christopher Li, Li Li, Annika Lindblom, Noralane Lindor, Roger L. Milne, Victor Moreno, Neil Murphy, Polly A. Newcomb, Deborah A. Nickerson, Kenneth Offit, Rachel Pearlman, Paul D. P. Pharoah, Elizabeth A. Platz, John D. Potter, Gad Rennert, Lori C. Sakoda, Clemens Schafmayer, Stephanie L. Schmit, Robert E. Schoen, Fredrick R. Schumacher, Martha L. Slattery, Yu-Ru Su, Catherine M. Tangen, Cornelia M. Ulrich, Franzel J. B. van Duijnhoven, Bethany Van Guelpen, Kala Visvanathan, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Xiaoliang Wang, Emily White, Alicja Wolk, Michael O. Woods, Graham Casey, Li Hsu, Mark A. Jenkins, Stephen B. Gruber, Ulrike Peters, Wei Zheng
Summary: This study identified multiple genes associated with colorectal cancer risk through a transcriptome-wide association study, including genes in novel loci. Furthermore, previously unreported genes were also discovered in known GWAS-identified loci. Through colocalization analysis, additional putative susceptibility genes were identified, providing new insights into the biological mechanisms underlying CRC development.
Article
Genetics & Heredity
Xinyuan Dong, Yu-Ru Su, Richard Barfield, Stephanie A. Bien, Qianchuan He, Tabitha A. Harrison, Jeroen R. Huyghe, Temitope O. Keku, Noralane M. Lindor, Clemens Schafmayer, Andrew T. Chan, Stephen B. Gruber, Mark A. Jenkins, Charles Kooperberg, Ulrike Peters, Li Hsu
Article
Oncology
Julia D. Labadie, Xinwei Hua, Tabitha A. Harrison, Barbara L. Banbury, Jeroen R. Huyghe, Wei Sun, Qian Shi, Greg Yothers, Steven R. Alberts, Frank A. Sinicrope, Richard M. Goldberg, Thomas J. George, Kathryn L. Penney, Amanda Phipps, Stacey A. Cohen, Ulrike Peters, Andrew T. Chan, Polly A. Newcomb
Summary: Two genetic variants in the RARA gene were significantly associated with severe skin toxicity induced by cetuximab in colon cancer patients, suggesting a potential target for risk stratification. Follow-up work could explore the use of retinoids in individuals with these variants to assess potential benefits in skin toxicity management.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Oncology
Xinwei Hua, James Y. Dai, Sara Lindstrom, Tabitha A. Harrison, Yi Lin, Steven R. Alberts, Elizabeth Alwers, Sonja Berndt, Hermann Brenner, Daniel D. Buchanan, Peter T. Campbell, Graham Casey, Jenny Chang-Claude, Steven Gallinger, Graham G. Giles, Richard M. Goldberg, Marc J. Gunter, Michael Hoffmeister, Mark A. Jenkins, Amit D. Joshi, Wenjie Ma, Roger L. Milne, Neil Murphy, Rish K. Pai, Lori C. Sakoda, Robert E. Schoen, Qian Shi, Martha L. Slattery, Mingyang Song, Emily White, Loic Le Marchand, Andrew T. Chan, Ulrike Peters, Polly A. Newcomb
Summary: This study utilized a Mendelian randomization approach to assess the association between CRP concentrations and colorectal cancer-specific survival, and found no causal effect of circulating CRP concentrations on colorectal cancer-specific survival. Further research on genetically determined levels of other inflammatory biomarkers is needed for colorectal cancer survival outcomes.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Oncology
Ivan Borozan, Syed H. Zaidi, Tabitha A. Harrison, Amanda Phipps, Jiayin Zheng, Stephen Lee, Quang M. Trinh, Robert S. Steinfelder, Jeremy Adams, Barbara L. Banbury, Sonja Berndt, Stefanie Brezina, Daniel D. Buchanan, Susan Bullman, Yin Cao, Alton B. Farris, Jane C. Figueiredo, Marios Giannakis, Lawrence E. Heisler, John L. Hopper, Yi Lin, Xuemei Luo, Reiko Nishihara, Elaine R. Mardis, Nickolas Papadopoulos, Conghui Qu, Emma E. G. Reid, Stephen N. Thibodeau, Sophia Harlid, Caroline Y. Um, Li Hsu, Andrea Gsur, Peter T. Campbell, Steven Gallinger, Polly A. Newcomb, Shuji Ogino, Wei Sun, Thomas J. Hudson, Vincent Ferretti, Ulrike Peters
Summary: This study found an association between F. nucleatum and its subspecies animalis with tumor characteristics and colorectal cancer-specific survival. The presence of F. nucleatum, particularly subspecies animalis, was associated with a higher colorectal cancer-specific mortality and specific somatic mutated genes.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Oncology
Hanla A. Park, Dominic Edelmann, Federico Canzian, Tabitha A. Harrison, Xinwei Hua, Qian Shi, Allison Silverman, Martin Schneider, Richard M. Goldberg, Steven R. Alberts, Michael Hoffmeister, Hermann Brenner, Andrew T. Chan, Ulrike Peters, Polly A. Newcomb, Jenny Chang-Claude
Summary: This study aimed to construct polygenic hazard scores (PHS) as predictive markers for oxaliplatin treatment outcome but could not be replicated in an independent cohort.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Oncology
Alexi N. Archambault, Jihyoun Jeon, Yi Lin, Minta Thomas, Tabitha A. Harrison, D. Timothy Bishop, Hermann Brenner, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Jane C. Figueiredo, Steven Gallinger, Stephen B. Gruber, Marc J. Gunter, Feng Guo, Michael Hoffmeister, Mark A. Jenkins, Temitope O. Keku, Loic Le Marchand, Li Li, Victor Moreno, Polly A. Newcomb, Rish Pai, Patrick S. Parfrey, Gad Rennert, Lori C. Sakoda, Jeffrey K. Lee, Martha L. Slattery, Mingyang Song, Aung Ko Win, Michael O. Woods, Neil Murphy, Peter T. Campbell, Yu-Ru Su, Iris Lansdorp-Vogelaar, Elisabeth F. P. Peterse, Yin Cao, Anne Zeleniuch-Jacquotte, Peter S. Liang, Mengmeng Du, Douglas A. Corley, Li Hsu, Ulrike Peters, Richard B. Hayes
Summary: This study developed risk prediction models for early-onset colorectal cancer (CRC) that incorporate an environmental risk score (ERS) and a polygenic risk score (PRS). The study found that increasing values of ERS and PRS were associated with increasing relative risks for early-onset CRC. Personal risk scores have the potential to identify individuals at differential relative and absolute risk for early-onset CRC, and may improve screening and outcomes.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2022)
Article
Oncology
Xiaoliang Wang, Efrat Amitay, Tabitha A. Harrison, Barbara L. Banbury, Sonja Berndt, Hermann Brenner, Daniel D. Buchanan, Peter T. Campbell, Yin Cao, Andrew T. Chan, Jenny Chang-Claude, Steven J. Gallinger, Marios Giannakis, Graham G. Giles, Marc J. Gunter, John L. Hopper, Mark A. Jenkins, Yi Lin, Victor Moreno, Reiko Nishihara, Polly A. Newcomb, Shuji Ogino, Amanda Phipps, Lori C. Sakoda, Robert E. Schoen, Martha L. Slattery, Mingyang Song, Wei Sun, Steven N. Thibodeau, Amanda E. Toland, Bethany Van Guelpen, Michael O. Woods, Li Hsu, Michael Hoffmeister, Ulrike Peters
Summary: Smoking is associated with differential risk of CRC subtypes defined by molecular characteristics, particularly higher risk for CIMP-positive and MSI-high subtypes.
JNCI CANCER SPECTRUM
(2021)
Article
Oncology
Alexi N. Archambault, Yi Lin, Jihyoun Jeon, Tabitha A. Harrison, D. Timothy Bishop, Hermann Brenner, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Jane C. Figueiredo, Steven Gallinger, Stephen B. Gruber, Marc J. Gunter, Michael Hoffmeister, Mark A. Jenkins, Temitope O. Keku, Loic Le Marchand, Li Li, Victor Moreno, Polly A. Newcomb, Rish Pai, Patrick S. Parfrey, Gad Rennert, Lori C. Sakoda, Robert S. Sandler, Martha L. Slattery, Mingyang Song, Aung Ko Win, Michael O. Woods, Neil Murphy, Peter T. Campbell, Yu-Ru Su, Anne Zeleniuch-Jacquotte, Peter S. Liang, Mengmeng Du, Li Hsu, Ulrike Peters, Richard B. Hayes
Summary: In this large study, several nongenetic risk factors associated with early-onset colorectal cancer were identified, providing a basis for targeted identification of high-risk individuals, which is crucial in mitigating the increasing burden of this disease.
JNCI CANCER SPECTRUM
(2021)
