Journal
JOURNAL OF GENERAL VIROLOGY
Volume 93, Issue -, Pages 1645-1648Publisher
SOC GENERAL MICROBIOLOGY
DOI: 10.1099/vir.0.042671-0
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Funding
- EU [FP7-GA258084]
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Exchange of gene segments between mammalian and avian influenza A viruses may lead to the emergence of potential pandemic influenza viruses. Since co-infection of single cells with two viruses is a prerequisite for reassortment to take place, we assessed frequencies of double-infection in vitro using influenza A/H5N1 and A/H1N1 viruses expressing the reporter genes eGFP or mCherry. Double-infected A549 and Madin-Darby canine kidney cells were detected by confocal microscopy and flow cytometry.
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