Journal
JOURNAL OF GENERAL VIROLOGY
Volume 94, Issue -, Pages 159-165Publisher
MICROBIOLOGY SOC
DOI: 10.1099/vir.0.046086-0
Keywords
-
Categories
Funding
- Japan Society for the Promotion of Science (JSPS KAKENHI) [24.1466]
- [KAKENHI 24580427]
- Grants-in-Aid for Scientific Research [24580427] Funding Source: KAKEN
Ask authors/readers for more resources
Papillomaviruses (PVs) have been widely identified among vertebrates, but have not yet been reported to infect yaks. We report, for the first time, a novel deltapapillomavirus that was associated with fibropapilloma in yak herds on the Qinghai-Tibetan Plateau. Six skin papilloma samples were collected and examined using histopathology, immunohistochemistry and PCR assays. The samples were identified as fibropapilloma and were found to contain PV antigens. Sequencing of diagnostic PCR products and the full-length genome revealed that all samples were infected with the same PV type. The whole virus genome was 7946 bp in length and possessed the common PV genomic organization. The virus was identified as a novel PV type and designated Bos grunniens papillomavirus type 1 (BgPV-1) based on the nucleotide sequence alignment of the L1 ORF. It is classified in the Delta-4 species of the genus Deltapapillomavirus based on phylogenetic analysis of the L1 ORF. Identification of this novel PV type provides further information about the pathology, development of diagnostic methods and evolutionary studies of the family Papillomaviridae.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available