H9 avian influenza reassortant with engineered polybasic cleavage site displays a highly pathogenic phenotype in chicken

H9N2 influenza virus acquires intravenous pathogenicity on the introduction of a pair of di-basic amino acid residues at the cleavage site of the hemagglutinin and consecutive passages in chickens

(2011) Kosuke Soda et al.   Virology Journal

Amino acids adjacent to the haemagglutinin cleavage site are relevant for virulence of avian influenza viruses of subtype H5

(2010) S. Gohrbandt et al.   JOURNAL OF GENERAL VIROLOGY

Insertion of a Multibasic Cleavage Motif into the Hemagglutinin of a Low-Pathogenic Avian Influenza H6N1 Virus Induces a Highly Pathogenic Phenotype

(2010) V. J. Munster et al.   JOURNAL OF VIROLOGY

Highly Pathogenic H5N1 Influenza Viruses Carry Virulence Determinants beyond the Polybasic Hemagglutinin Cleavage Site

(2010) Jessica Bogs et al.   PLoS One

Avian influenza: our current understanding

(2010) David L. Suarez   ANIMAL HEALTH RESEARCH REVIEWS

Serological reports of human infections of H7 and H9 avian influenza viruses in northern China

(2009) Na Jia et al.   JOURNAL OF CLINICAL VIROLOGY

The NS Segment of an H5N1 Highly Pathogenic Avian Influenza Virus (HPAIV) Is Sufficient To Alter Replication Efficiency, Cell Tropism, and Host Range of an H7N1 HPAIV

(2009) W. Ma et al.   JOURNAL OF VIROLOGY

Acquisition of a Polybasic Hemagglutinin Cleavage Site by a Low-Pathogenic Avian Influenza Virus Is Not Sufficient for Immediate Transformation into a Highly Pathogenic Strain

(2009) O. Stech et al.   JOURNAL OF VIROLOGY

A Genetically Engineered Waterfowl Influenza Virus with a Deletion in the Stalk of the Neuraminidase Has Increased Virulence for Chickens

(2009) S. Munier et al.   JOURNAL OF VIROLOGY

Antibodies against H5 and H9 Avian Influenza among Poultry Workers in China

(2009) Ming Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alterations in caspase cleavage motifs of NP and M2 proteins attenuate virulence of a highly pathogenic avian influenza virus

(2009) Oleg P. Zhirnov et al.   VIROLOGY

Phylogenetic and biological characterization of highly pathogenic H5N1 avian influenza viruses (Vietnam 2005) in chickens and ducks

(2009) J. Pfeiffer et al.   VIRUS RESEARCH

NP, PB1, and PB2 Viral Genes Contribute to Altered Replication of H5N1 Avian Influenza Viruses in Chickens

(2008) J. L. Wasilenko et al.   JOURNAL OF VIROLOGY

Rapid and reliable universal cloning of influenza A virus genes by target-primed plasmid amplification

(2008) J. Stech et al.   NUCLEIC ACIDS RESEARCH

Animal influenza epidemiology

(2008) M.F. Ducatez et al.   VACCINE

Protection of chickens against H5N1 highly pathogenic avian influenza virus infection by live vaccination with infectious laryngotracheitis virus recombinants expressing H5 hemagglutinin and N1 neuraminidase

(2008) Sophia P. Pavlova et al.   VACCINE

Swine infection with H9N2 influenza viruses in China in 2004

(2008) Yan-Long Cong et al.   VIRUS GENES